Search Results - "Wiley, Ronald G"

Behavioral and Anatomical Characterization of the Bilateral Sciatic Nerve Chronic Constriction (bCCI) Injury: Correlation of Anatomic Changes and Responses to Cold Stimuli by Datta, Sukdeb, Chatterjee, Koel, Kline, Robert H, Wiley, Ronald G

“…Background: Unilateral constrictive sciatic nerve injury (uCCI) is a common neuropathic pain model. However, the bilateral constrictive injury (bCCI) model is…”
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Inhibition of Hyperalgesia by Ablation of Lamina I Spinal Neurons Expressing the Substance P Receptor by Mantyh, Patrick W., Rogers, Scott D., Honore, Prisca, Allen, Brian J., Ghilardi, Joseph R., Li, Jun, Daughters, Randy S., Lappi, Douglas A., Wiley, Ronald G., Simone, Donald A.

“…Substance P is released in the spinal cord in response to painful stimuli, but its role in nociceptive signaling remains unclear. When a conjugate of substance…”
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Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn by Nelson, Tyler S., Fu, Weisi, Donahue, Renée R., Corder, Gregory F., Hökfelt, Tomas, Wiley, Ronald G., Taylor, Bradley K.

“…Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibitory control of neuropathic pain, but its mechanism of action is complicated by the expression…”
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Inhibition in the dorsal horn by Wiley, Ronald G.

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Neurobehavioral mutants identified in an ENU-mutagenesis project by Cook, Melloni N, Dunning, Jonathan P, Wiley, Ronald G, Chesler, Elissa J, Johnson, Dabney K, Miller, Darla R, Goldowitz, Dan

“…We report on a battery of behavioral screening tests that successfully identified several neurobehavioral mutants among a large-scale ENU-mutagenized mouse…”
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Selective Immunotoxic Lesions of Basal Forebrain Cholinergic Cells: Effects on Learning and Memory in Rats by Baxter, Mark G, Bucci, David J, Gorman, Linda K, Wiley, Ronald G, Gallagher, Michela

“…Male Long-Evans rats were given injections of either 192 IgG-saporin, an apparently selective toxin for basal forebrain cholinergic neurons (LES), or vehicle…”
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Substance P receptor-expressing dorsal horn neurons: Lessons from the targeted cytotoxin, substance P-saporin by Wiley, Ronald G.

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Spinal mu-opioid receptor-expressing dorsal horn neurons: role in nociception and morphine antinociception by Kline, 4th, Robert H, Wiley, Ronald G

“…The role of spinal cord mu-opioid receptor (MOR)-expressing dorsal horn neurons in nociception and morphine analgesia is incompletely understood. Using…”
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Enhancement of Cortical Plasticity by Behavioral Training in Acetylcholine-Depleted Adult Rats by Sachdev, Robert N. S, Egli, Mark, Stonecypher, Mark, Wiley, Ronald G, Ebner, Ford F

“…  1 Department of Psychology, Vanderbilt University, Nashville 37240; and   2 Department of Neurology, Veterans Affairs Medical Center, Nashville, Tennessee…”
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Targeted toxins in pain by Wiley, Ronald G, Lappi, Douglas A

“…Although only recently applied to the study of nociception, ‘molecular neurosurgery’, producing highly selective neural lesions using targeted cytotoxins, has…”
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Neuronal lesioning with axonally transported toxins by Wiley, Ronald G, Kline IV, Robert H

“…Axonally transported toxins can be used to make selective lesions of the nervous system. Collectively, these techniques are termed ‘molecular neurosurgery’…”
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Parametric analysis of thermal preference following sleep deprivation in the rat by Harvey, Mark T., Kline, Robert H., May, Michael E., Roberts, A. Celeste, Valdovinos, Maria G., Wiley, Ronald G., Kennedy, Craig H.

“…▶ A thermal place preference task was developed that allows rats to chose between floors of differing temperatures. ▶ A parametric temperature analysis showed…”
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Comparison of Operant Escape and Innate Reflex Responses to Nociceptive Skin Temperatures Produced by Heat and Cold Stimulation of Rats by Vierck, Charles J, Kline, Robert, Wiley, Ronald G

“…In behavioral tests, rats performed learned escape responses to thermal stimulation of the paws by 44.0, 47.0, or 0.3 °C. Licking, guarding, and jumping…”
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Selective Immunotoxic Lesions of Basal Forebrain Cholinergic Cells: Effects on Learning and Memory in Rats by Baxter, Mark G, Bucci, David J, Gorman, Linda K, Wiley, Ronald G, Gallagher, Michela

“…Male Long-Evans rats were given injections of either 192 IgG-saporin, an apparently selective toxin for basal forebrain cholinergic neurons (LES), or vehicle…”
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Neural lesioning with ribosome-inactivating proteins: suicide transport and immunolesioning by Wiley, R G

“…Toxic lectins, plant proteins that inactivate ribosomes, irreversibly inhibit protein synthesis with high efficiency. After intraneural (subepineurial)…”
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Nociceptor and age specific effects of REM sleep deprivation induced hyperalgesia by May, Michael E., Harvey, Mark T., Valdovinos, Maria G., Kline, Robert H., Wiley, Ronald G., Kennedy, Craig H.

“…REM sleep deprivation (REMSD) has been shown to increase rates of negatively reinforced operant behavior, but not operant responding maintained by positive…”
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Assessment of pain in laboratory animals: a comment on Mogil and Crager (2004) by Vierck, Charles J., Mauderli, Andre P., Wiley, Ronald G.

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Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat by Levey, A I, Edmunds, S M, Hersch, S M, Wiley, R G, Heilman, C J

“…The m2 muscarinic acetylcholine receptor gene is expressed at high levels in basal forebrain, but the paucity of information about localization of the encoded…”
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Immunotoxins and neuropeptide-toxin conjugates experimental applications by Lappi, Dougles A, Wiley, Ronald G

“…The use of targeted toxins in research applications has recently grown considerably. The ability to remove a few specific cells, even when surrounded by…”
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192 IgG-saporin: I. Specific lethality for cholinergic neurons in the basal forebrain of the rat by Book, A A, Wiley, R G, Schweitzer, J B

“…An immunotoxin (IT) composed of a monoclonal antibody to the nerve growth factor (NGF) receptor, 192 IgG, chemically linked to saporin, 192 IgG-saporin, was…”
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