Search Results - "Wiles, J"

Photoredox‐Mediated Net‐Neutral Radical/Polar Crossover Reactions by Wiles, Rebecca J., Molander, Gary A.

“…Radical/Polar Crossover (RPC) chemistry is a rapidly growing subset of photoredox catalysis that is characterized by transformations featuring both radical and…”
Get full text

Photoredox Generation of Carbon‐Centered Radicals Enables the Construction of 1,1‐Difluoroalkene Carbonyl Mimics by Lang, Simon B., Wiles, Rebecca J., Kelly, Christopher B., Molander, Gary A.

“…Described is a facile, scalable route to access functional‐group‐rich gem‐difluoroalkenes. Using visible‐light‐activated catalysts in conjunction with an…”
Get full text

Swimming motility of a gut bacterial symbiont promotes resistance to intestinal expulsion and enhances inflammation by Wiles, Travis J, Schlomann, Brandon H, Wall, Elena S, Betancourt, Reina, Parthasarathy, Raghuveer, Guillemin, Karen

“…Some of the densest microbial ecosystems in nature thrive within the intestines of humans and other animals. To protect mucosal tissues and maintain immune…”
Get full text

The Other Side of the Coin: What Beneficial Microbes Can Teach Us about Pathogenic Potential by Wiles, Travis J., Guillemin, Karen

“…Koch's postulates and molecular Koch's postulates have made an indelible mark on how we study and classify microbes, particularly pathogens. However, rigid…”
Get full text

Host Gut Motility Promotes Competitive Exclusion within a Model Intestinal Microbiota by Wiles, Travis J, Jemielita, Matthew, Baker, Ryan P, Schlomann, Brandon H, Logan, Savannah L, Ganz, Julia, Melancon, Ellie, Eisen, Judith S, Guillemin, Karen, Parthasarathy, Raghuveer

“…The gut microbiota is a complex consortium of microorganisms with the ability to influence important aspects of host health and development. Harnessing this…”
Get full text

The enteric nervous system promotes intestinal health by constraining microbiota composition by Rolig, Annah S, Mittge, Erika K, Ganz, Julia, Troll, Josh V, Melancon, Ellie, Wiles, Travis J, Alligood, Kristin, Stephens, W Zac, Eisen, Judith S, Guillemin, Karen

“…Sustaining a balanced intestinal microbial community is critical for maintaining intestinal health and preventing chronic inflammation. The gut is a highly…”
Get full text

Bacterial Cohesion Predicts Spatial Distribution in the Larval Zebrafish Intestine by Schlomann, Brandon H., Wiles, Travis J., Wall, Elena S., Guillemin, Karen, Parthasarathy, Raghuveer

“…Are there general biophysical relationships governing the spatial organization of the gut microbiome? Despite growing realization that spatial structure is…”
Get full text

Is screen time associated with anxiety or depression in young people? Results from a UK birth cohort by Khouja, Jasmine N, Munafò, Marcus R, Tilling, Kate, Wiles, Nicola J, Joinson, Carol, Etchells, Peter J, John, Ann, Hayes, Fiona M, Gage, Suzanne H, Cornish, Rosie P

“…There is limited and conflicting evidence for associations between use of screen-based technology and anxiety and depression in young people. We examined…”
Get full text

Left Ventricular Function and Cardiac Biomarker Release—The Influence of Exercise Intensity, Duration and Mode: A Systematic Review and Meta-Analysis by Donaldson, J. A., Wiles, J. D., Coleman, D. A., Papadakis, M., Sharma, R., O’Driscoll, J. M.

“…Objective We performed a systematic review, meta-analysis and meta-regression of exercise studies that sought to determine the relationship between cardiac…”
Get full text

Effect of isometric exercise on resting blood pressure: a meta analysis by Owen, A, Wiles, J, Swaine, I

“…Dynamic physical exercise (walking, swimming, and so on) is an important component of lifestyle changes to reduce blood pressure; however, many individuals are…”
Get full text

Cultivating Healthy Connections: Exploring and Engineering the Microbial Flow That Shapes Microbiomes by Wiles, Travis J.

“…Our view of the microbial world has undergone a radical transformation over the past decade. For most of the 20th century, medical microbiological research was…”
Get full text

Modernized Tools for Streamlined Genetic Manipulation and Comparative Study of Wild and Diverse Proteobacterial Lineages by Wiles, Travis J, Wall, Elena S, Schlomann, Brandon H, Hay, Edouard A, Parthasarathy, Raghuveer, Guillemin, Karen

“…Correlating the presence of bacteria and the genes they carry with aspects of plant and animal biology is rapidly outpacing the functional characterization of…”
Get full text

Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane by Connors, Caroline Q, Mauro, Michael S, Wiles, J Tristian, Countryman, Andrew D, Martin, Sophia L, Lacroix, Benjamin, Shirasu-Hiza, Mimi, Dumont, Julien, Kasza, Karen E, Davies, Timothy R, Canman, Julie C

“…Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an actomyosin contractile ring at the…”
Get full text

Toward a Unified Mechanism for Oxoammonium Salt-Mediated Oxidation Reactions: A Theoretical and Experimental Study Using a Hydride Transfer Model by Hamlin, Trevor A, Kelly, Christopher B, Ovian, John M, Wiles, Rebecca J, Tilley, Leon J, Leadbeater, Nicholas E

“…A range of oxoammonium salt-based oxidation reactions have been explored computationally using density functional theory (DFT), and the results have been…”
Get full text

Ketamine’s rapid antidepressant effects are mediated by Ca2+-permeable AMPA receptors by Zaytseva, Anastasiya, Bouckova, Evelina, Wiles, McKennon J, Wustrau, Madison H, Schmidt, Isabella G, Mendez-Vazquez, Hadassah, Khatri, Latika, Kim, Seonil

“…Ketamine is shown to enhance excitatory synaptic drive in multiple brain areas, which is presumed to underlie its rapid antidepressant effects. Moreover,…”
Get full text

Facilitated physical activity as a treatment for depressed adults: randomised controlled trial by Chalder, Melanie, Wiles, Nicola J, Campbell, John, Hollinghurst, Sandra P, Haase, Anne M, Taylor, Adrian H, Fox, Kenneth R, Costelloe, Ceire, Searle, Aidan, Baxter, Helen, Winder, Rachel, Wright, Christine, Turner, Katrina M, Calnan, Michael, Lawlor, Deborah A, Peters, Tim J, Sharp, Deborah J, Montgomery, Alan A, Lewis, Glyn

“…Objective To investigate the effectiveness of facilitated physical activity as an adjunctive treatment for adults with depression presenting in primary…”
Get full text

Improved gross efficiency during long duration submaximal cycling following a short-term high carbohydrate diet by Cole, M, Coleman, D, Hopker, J, Wiles, J

“…To assess the effect of dietary manipulation on gross efficiency (GE), 15 trained male cyclists completed 3×2 h tests at submaximal exercise intensity (60%…”
Get more information

Oxidative Esterification of Aldehydes Using a Recyclable Oxoammonium Salt by Kelly, Christopher B, Mercadante, Michael A, Wiles, Rebecca J, Leadbeater, Nicholas E

“…A simple, high yielding, rapid route for the oxidative esterification of a wide range aldehydes to hexafluoroisopropyl (HFIP) esters using the oxoammonium salt…”
Get full text

Temporally selective contextual encoding in the dentate gyrus of the hippocampus by Rangel, L.M., Alexander, A.S., Aimone, J.B., Wiles, J., Gage, F.H., Chiba, A.A., Quinn, L.K.

“…A recent model of the hippocampus predicts that the unique properties of the dentate gyrus allow for temporal separation of events. This temporal separation is…”
Get full text

Sea surface cooling at the Equator by subsurface mixing in tropical instability waves by Moum, J. N, Lien, R.-C, Perlin, A, Nash, J. D, Gregg, M. C, Wiles, P. J

“…Changes in sea surface temperature of equatorial waters have critical effects on the large-scale atmospheric circulation. So far, large-scale, energetic…”
Get full text