Search Results - "Wildering, Willem C."

Cortisol modulates calcium release-activated calcium channel gating in fish hepatocytes by Das, Chinmayee, Rout, Manoj K., Wildering, Willem C., Vijayan, Mathilakath M.

“…Glucocorticoids (GCs) are rapidly released in response to stress and play an important role in the physiological adjustments to re-establish homeostasis. The…”
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Linking the 'why' and 'how' of ageing: evidence for somatotropic control of long-term memory function in the pond snail Lymnaea stagnalis by de Weerd, Lis, Hermann, Petra M, Wildering, Willem C

“…Organisms live on a budget; hence, they cannot maximize all their activities at the same time. Instead, they must prioritize how they spend limiting resources…”
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Phospholipase A2 - nexus of aging, oxidative stress, neuronal excitability, and functional decline of the aging nervous system? Insights from a snail model system of neuronal aging and age-associated memory impairment by Hermann, Petra M, Watson, Shawn N, Wildering, Willem C

“…The aging brain undergoes a range of changes varying from subtle structural and physiological changes causing only minor functional decline under healthy…”
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Failure of delayed nonsynaptic neuronal plasticity underlies age-associated long-term associative memory impairment by Watson, Shawn N, Risling, Tara E, Hermann, Petra M, Wildering, Willem C

“…Cognitive impairment associated with subtle changes in neuron and neuronal network function rather than widespread neuron death is a feature of the normal…”
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Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment by Hermann, Petra M, Perry, Alexander C, Hamad, Izen, Wildering, Willem C

“…Plasma membrane efflux transporters play crucial roles in the removal and release of both harmful and beneficial substances from the interior of cells and…”
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Embryonic exposure to model naphthenic acids delays growth and hatching in the pond snail Lymnaea stagnalis by Johnston, Christina U., Clothier, Lindsay N., Quesnel, Dean M., Gieg, Lisa M., Chua, Gordon, Hermann, Petra M., Wildering, Willem C.

“…Naphthenic acids (NAs), a class of structurally diverse carboxylic acids with often complex ring structures and large aliphatic tail groups, are important…”
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Redox agents modulate neuronal activity and reproduce physiological aspects of neuronal aging by Watson, Shawn N, Nelson, Mark A, Wildering, Willem C

“…Abstract The high oxygen consumption and post-mitotic nature of the central nervous system (CNS) makes it particularly susceptible to oxidative stress, the…”
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Evidence for age-dependent mating strategies in the simultaneous hermaphrodite snail, Lymnaea stagnalis (L.) by Hermann, Petra M, Genereux, Brad, Wildering, Willem C

“…In many mating systems female reproductive capacity is a limiting resource over which males will compete. As a consequence, males and females have usually…”
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Evidence for inflammation-mediated memory dysfunction in gastropods: putative PLA2 and COX inhibitors abolish long-term memory failure induced by systemic immune challenges by Hermann, Petra M, Park, Deborah, Beaulieu, Emily, Wildering, Willem C

“…Previous studies associate lipid peroxidation with long-term memory (LTM) failure in a gastropod model (Lymnaea stagnalis) of associative learning and memory…”
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Phospholipase A2 : The key to reversing long-term memory impairment in a gastropod model of aging by Watson, Shawn N, Wright, Natasha, Hermann, Petra M, Wildering, Willem C

“…Abstract Memory failure associated with changes in neuronal circuit functions rather than cell death is a common feature of normal aging in diverse animal…”
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Diminishing glutathione availability and age-associated decline in neuronal excitability by Watson, Shawn N, Lee, Jonathon R, Risling, Tara E, Hermann, Petra M, Wildering, Willem C

“…Abstract Oxidative stress is frequently implicated in diminished electrical excitability of aging neurons yet the foundations of this phenomenon are poorly…”
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Oxidative-stress induced increase in circulating fatty acids does not contribute to phospholipase A2-dependent appetitive long-term memory failure in the pond snail Lymnaea stagnalis by Beaulieu, Emily, Ioffe, Julie, Watson, Shawn N, Hermann, Petra M, Wildering, Willem C

“…Reactive oxygen species (ROS) are essential for normal physiological functioning of the brain. However, uncompensated increase in ROS levels may results in…”
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Impairment of Long-Term Associative Memory in Aging Snails (Lymnaea stagnalis) by Hermann, Petra M, Lee, Arden, Hulliger, Sara, Minvielle, Michelle, Ma, Bonita, Wildering, Willem C

“…Age-dependent impairment in learning and memory functions occurs in many animal species, including humans. Although cell death contributes to age-related…”
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RGD-dependent mechanisms in the endoneurial phagocyte response and axonal regeneration in the nervous system of the snail Lymnaea stagnalis by Hermann, Petra M, Nicol, Jennifer J, Bulloch, Andrew G M, Wildering, Willem C

“…Activation of phagocytic cells in the injury zone is a crucial step in the regeneration of peripheral axons. Many aspects of the mechanisms underlying the…”
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Rapid Neuromodulatory Actions of Integrin Ligands by Wildering, Willem C, Hermann, Petra M, Bulloch, Andrew G. M

“…Extracellular matrix (ECM) proteins and their receptors, the integrins, actively participate in the control of many fundamental cellular functions in the…”
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Epidermal growth factor-dependent enhancement of axonal regeneration in the pond snail Lymnaea stagnalis: Role of phagocyte survival by Hermann, Petra M., Nicol, Jennifer J., Nagle, Gregg T., Bulloch, Andrew G.M., Wildering, Willem C.

“…Peripheral nerve injury triggers complex responses from neuronal as well as from multiple nonneuronal cell types. These responses are coordinated by a wide…”
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Lymnaea Epidermal Growth Factor Promotes Axonal Regeneration in CNS Organ Culture by Wildering, Willem C, Hermann, Petra M, Bulloch, Andrew G. M

“…Members of the epidermal growth factor (EGF) family are frequently implicated in the injury response of the mammalian nervous system. Although this implication…”
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Nongenomic action of cortisol in rainbow trout hepatocytes by Vijayan, Matt, Das, Chinmayee, Wildering, Willem C

“…Abstract only Cortisol rapidly activates cell signalling in trout hepatocytes; however, the mechanisms are far from clear. We tested the hypothesis that rapid…”
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Neurotrophic Actions of a Novel Molluscan Epidermal Growth Factor by Hermann, Petra M, van Kesteren, Ronald E, Wildering, Willem C, Painter, Sherry D, Reno, John M, Smith, John S, Kumar, Santosh B, Geraerts, Wijnand P. M, Ericsson, Lowell H, Smit, August B, Bulloch, Andrew G. M, Nagle, Gregg T

“…The mammalian epidermal growth factor (EGF) is expressed in the developing and adult CNS, and it has been implicated in the control of cell proliferation,…”
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Functional Recovery of Respiratory Behavior During Axonal Regeneration in Snails (Lymnaea stagnalis ) Is Experience Dependent by Hermann, Petra M, Wildering, Willem C, Bulloch, Andrew G. M

“…This study investigated the role of experience in recovery of pulmonary respiration during axonal regeneration in Lymnaea stagnalis. Pulmonary respiration…”
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