Search Results - "Wilder, R."

Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration by Scott, R. Wilder, Arostegui, Martin, Schweitzer, Ronen, Rossi, Fabio M.V., Underhill, T. Michael

“…Many adult tissues contain resident stem cells, such as the Pax7+ satellite cells within skeletal muscle, that regenerate parenchymal elements following…”
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Cellular taxonomy of Hic1+ mesenchymal progenitor derivatives in the limb: from embryo to adult by Arostegui, Martin, Scott, R. Wilder, Böse, Kerstin, Underhill, T. Michael

“…Tissue development and regeneration rely on the cooperation of multiple mesenchymal progenitor (MP) subpopulations. We recently identified Hic1 as a marker of…”
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Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing by Abbasi, Sepideh, Sinha, Sarthak, Labit, Elodie, Rosin, Nicole L., Yoon, Grace, Rahmani, Waleed, Jaffer, Arzina, Sharma, Nilesh, Hagner, Andrew, Shah, Prajay, Arora, Rohit, Yoon, Jessica, Islam, Anowara, Uchida, Aya, Chang, Chih Kai, Stratton, Jo Anne, Scott, R. Wilder, Rossi, Fabio M.V., Underhill, T. Michael, Biernaskie, Jeff

“…Dermal fibroblasts exhibit considerable heterogeneity during homeostasis and in response to injury. Defining lineage origins of reparative fibroblasts and…”
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Errors and losses impact on planar integrated photonic circuits fidelity by Cardoso, Wilder R.

“…Every manufacturing or synthesis process suffers from possible errors or inaccuracies. Thus, this article presents a theoretical study on how such…”
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Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis by Cait, Jessica, Cait, Alissa, Scott, R Wilder, Winder, Charlotte B, Mason, Georgia J

“…Over 120 million mice and rats are used annually in research, conventionally housed in shoebox-sized cages that restrict natural behaviours (e.g. nesting and…”
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Nosemosis negatively affects honeybee survival: experimental and meta-analytic evidence by Ostap-Chec, Monika, Cait, Jessica, Scott, R. Wilder, Arct, Aneta, Moroń, Dawid, Rapacz, Marcin, Miler, Krzysztof

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Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors by Soliman, Hesham, Paylor, Ben, Scott, R. Wilder, Lemos, Dario R., Chang, ChihKai, Arostegui, Martin, Low, Marcela, Lee, Christina, Fiore, Daniela, Braghetta, Paola, Pospichalova, Vendula, Barkauskas, Christina E., Korinek, Vladimir, Rampazzo, Alessandra, MacLeod, Kathleen, Underhill, T. Michael, Rossi, Fabio M.V.

“…The cardiac stroma contains multipotent mesenchymal progenitors. However, lineage relationships within cardiac stromal cells are poorly defined. Here, we…”
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Hic1 identifies a specialized mesenchymal progenitor population in the embryonic limb responsible for bone superstructure formation by Arostegui, Martin, Scott, R. Wilder, Underhill, T. Michael

“…The musculoskeletal system relies on the integration of multiple components with diverse physical properties, such as striated muscle, tendon, and bone, that…”
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Benchmarking bulk and single-cell variant calling approaches on Chromium scRNA-seq and scATAC-seq libraries by Wiens, Matthew V J, Farahani, Hossein, Scott, R Wilder, Underhill, T Michael, Bashashati, Ali

“…Single-cell sequencing methodologies such as scRNA-seq and scATAC-seq have become widespread and effective tools to interrogate tissue composition…”
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Podocalyxin is required for maintaining blood–brain barrier function during acute inflammation by Cait, Jessica, Hughes, Michael R., Zeglinski, Matthew R., Chan, Allen W., Osterhof, Sabrina, Scott, R. Wilder, Hernaez, Diana Canals, Cait, Alissa, Vogl, A. Wayne, Bernatchez, Pascal, Underhill, T. Michael, Granville, David J., Murphy, Timothy H., Roskelley, Calvin D., McNagny, Kelly M.

“…Podocalyxin (Podxl) is broadly expressed on the luminal face of most blood vessels in adult vertebrates, yet its function on these cells is poorly defined. In…”
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Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice by Chow, Leola N, Schreiner, Petra, Ng, Betina Y Y, Lo, Bernard, Hughes, Michael R, Scott, R Wilder, Gusti, Vionarica, Lecour, Samantha, Simonson, Eric, Manisali, Irina, Barta, Ingrid, McNagny, Kelly M, Crawford, Jason, Webb, Murray, Underhill, T Michael

“…Modulation of chemokine CXCL12 and its receptor CXCR4 has been implicated in attenuation of bleomycin (BLM)-induced pulmonary fibrosis and carbon tetrachloride…”
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Single-cell analysis of mesenchymal cells in permeable neural vasculature reveals novel diverse subpopulations of fibroblasts by Bastedo, William E, Scott, R Wilder, Arostegui, Martin, Underhill, T Michael

“…In the choroid plexus and pituitary gland, vasculature is known to have a permeable, fenestrated phenotype which allows for the free passage of molecules in…”
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Development and function of smooth muscle cells is modulated by Hic1 in mouse testis by Uchida, Aya, Sakib, Sadman, Labit, Elodie, Abbasi, Sepideh, Scott, R Wilder, Underhill, T Michael, Biernaskie, Jeff, Dobrinski, Ina

“…In mammalian testis, contractile peritubular myoid cells (PMCs) regulate the transport of sperm and luminal fluid, while secreting growth factors and…”
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Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing by Abbasi, Sepideh, Sinha, Sarthak, Labit, Elodie, Rosin, Nicole L., Yoon, Grace, Rahmani, Waleed, Jaffer, Arzina, Sharma, Nilesh, Hagner, Andrew, Shah, Prajay, Arora, Rohit, Yoon, Jessica, Islam, Anowara, Uchida, Aya, Chang, Chih Kai, Stratton, Jo Anne, Scott, R. Wilder, Rossi, Fabio M.V., Underhill, T. Michael, Biernaskie, Jeff

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The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection by Lo, Bernard C, Canals Hernaez, Diana, Scott, R Wilder, Hughes, Michael R, Shin, Samuel B, Underhill, T Michael, Takei, Fumio, McNagny, Kelly M

“…Innate lymphoid cells (ILCs) are critical for host defense and tissue repair but can also contribute to chronic inflammatory diseases. The transcription factor…”
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Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability by Benabdallah, Nezha S., Dalal, Vineet, Scott, R. Wilder, Marcous, Fady, Sotiriou, Afroditi, Kommoss, Felix K. F., Pejkovska, Anastasija, Gaspar, Ludmila, Wagner, Lena, Sánchez-Rivera, Francisco J., Ta, Monica, Thornton, Shelby, Nielsen, Torsten O., Underhill, T. Michael, Banito, Ana

“…The SS18-SSX fusion drives oncogenic transformation in synovial sarcoma by bridging SS18, a member of the mSWI/SNF (BAF) complex, to Polycomb repressive…”
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Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling by Hanker, A B, Mitin, N, Wilder, R S, Henske, E P, Tamanoi, F, Cox, A D, Der, C J

“…The Rheb1 and Rheb2 small GTPases and their effector mTOR are aberrantly activated in human cancer and are attractive targets for anti-cancer drug discovery…”
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Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo by Basha, Genc, Ordobadi, Mina, Scott, Wilder R, Cottle, Andrew, Liu, Yan, Wang, Haitang, Cullis, Pieter R

“…Sclerostin is a protein secreted by osteocytes that is encoded by the SOST gene; it decreases bone formation by reducing osteoblast differentiation through…”
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The role of zonal winds in the production of a pre-reversal enhancement in the vertical ion drift in the low latitude ionosphere by Heelis, R. A., Crowley, G., Rodrigues, F., Reynolds, A., Wilder, R., Azeem, I., Maute, A.

“…The evolution of the pre‐reversal enhancement in the vertical ion drift in the equatorialFregion is described via an examination of the current systems…”
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Laboratory Study of Collisionless Magnetic Reconnection by Ji, H., Yoo, J., Fox, W., Yamada, M., Argall, M., Egedal, J., Liu, Y.-H., Wilder, R., Eriksson, S., Daughton, W., Bergstedt, K., Bose, S., Burch, J., Torbert, R., Ng, J., Chen, L.-J.

“…A concise review is given on the past two decades’ results from laboratory experiments on collisionless magnetic reconnection in direct relation with space…”
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