Search Results - "Wilde, Aimee D."
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Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection
Published in PLoS pathogens (01-12-2015)“…Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues,…”
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Journal Article -
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S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking
Published in Cell reports (Cambridge) (27-02-2018)“…Clinical severity of Staphylococcus aureus respiratory infection correlates with alpha toxin (AT) expression. AT activates the NLRP3 inflammasome; deletion of…”
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Repurposing the Nonsteroidal Anti-inflammatory Drug Diflunisal as an Osteoprotective, Antivirulence Therapy for Staphylococcus aureus Osteomyelitis
Published in Antimicrobial agents and chemotherapy (01-09-2016)“…Staphylococcus aureus osteomyelitis is a common and debilitating invasive infection of bone. Treatment of osteomyelitis is confounded by widespread…”
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MicroLESA: Integrating Autofluorescence Microscopy, In Situ Micro-Digestions, and Liquid Extraction Surface Analysis for High Spatial Resolution Targeted Proteomic Studies
Published in Analytical chemistry (Washington) (18-06-2019)“…The ability to target discrete features within tissue using liquid surface extractions enables the identification of proteins while maintaining the spatial…”
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Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection: e1005341
Published in PLoS pathogens (01-12-2015)“…Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues,…”
Get full text
Journal Article