Effect of cardiopulmonary bypass on gastrointestinal perfusion and function

Effect of cardiopulmonary bypass on gastrointestinal perfusion and function

Gastric mucosal tonometry was used to determine the adequacy of gastrointestinal perfusion in 10 patients undergoing elective myccardial revascularization. Patients were prospectively randomized to receive either pulsatile or nonpulsatile flow during cardlopulmonary bypass. All patients showed a red...

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Bibliographic Details
Published in:The Annals of thoracic surgery Vol. 57; no. 2; pp. 371 - 375
Main Authors: Gaer, Jullien A.R., Shaw, Andrew D.S., Wild, Rachel, Swift, R.Ian, Munsch, Christopher M., Smith, Peter L.C., Taylor, Kenneth M.
Format: Journal Article
Language:English
Published: New York, NY Elsevier Inc 01-02-1994
Elsevier Science
Subjects:
Acidosis - blood
Anesthesia
Anesthesia depending on type of surgery
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cardiopulmonary Bypass - methods
Female
Gastric Mucosa - blood supply
Humans
Hydrogen-Ion Concentration
Male
Medical sciences
Middle Aged
Prospective Studies
Pulsatile Flow
Regional Blood Flow
Thoracic and cardiovascular surgery. Cardiopulmonary bypass
Cardiopulmonary bypass
Human
Stomach
Digestive system
Surgery
Heart disease
pH
Cardiovascular disease
Biological effect
Hemodynamics
Gastrointestinal
Revascularization
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Summary:Gastric mucosal tonometry was used to determine the adequacy of gastrointestinal perfusion in 10 patients undergoing elective myccardial revascularization. Patients were prospectively randomized to receive either pulsatile or nonpulsatile flow during cardlopulmonary bypass. All patients showed a reduction in gastric mucosal perfusion during bypass, manifested by a reduction in the gastric mucosal pH, which occurred independently of variations in too arterial pH. In the group of patients receiving nonpuisatile flow, this reduction was significantly greater ( p < 0.05). Cardiopulmonary bypass using nonpulsatife flow is associated with the development of a gastric mucosal acidosis, which may have implications for the development of postoperative complications.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-News-3
content type line 23
ISSN:0003-4975
1552-6259
DOI:10.1016/0003-4975(94)90999-7