Search Results - "Wild, J.R."

Nanoparticle-based optical biosensors for the direct detection of organophosphate chemical warfare agents and pesticides by Simonian, A.L., Good, T.A., Wang, S.-S., Wild, J.R.

“…Neurotoxic organophosphates (OP) have found widespread use in the environment for insect control. In addition, there is the increasing threat of use of OP…”
Get full text

Enzyme-based biosensor for the direct detection of fluorine-containing organophosphates by Simonian, A.L, Grimsley, J.K, Flounders, A.W, Schoeniger, J.S, Cheng, Tu-Chen, DeFrank, J.J, Wild, J.R

“…The ability of the enzyme organophosphorus acid anhydrolase (OPAA) to selectively hydrolyze the PF bond of fluorine containing organophosphates has been used…”
Get full text

The development of a new biosensor based on recombinant E. coli for the direct detection of organophosphorus neurotoxins by Rainina, E.I., Efremenco, E.N., Varfolomeyev, S.D., Simonian, A.L., Wild, J.R.

“…A new biosensor for the direct detection of organophosphorus (OP) neurtoxins has been developed utilizing cryoimmobilized, recombinant E. coli cells capable of…”
Get full text

Characterization of P-S Bond Hydrolysis in Organophosphorothioate Pesticides by Organophosphorus Hydrolase by Lai, K., Stolowich, N.J., Wild, J.R.

“…The extensive use of organophosphorothioate insecticides in agriculture has resulted in the risk of environmental contamination with a variety of broadly based…”
Get full text

Encapsulation of phosphotriesterase within murine erythrocytes by Pei, L, Omburo, G, McGuinn, W D, Petrikovics, I, Dave, K, Raushel, F M, Wild, J R, DeLoach, J R, Way, J L

“…A new conceptual approach was employed to antagonize organophosphorus intoxication by using resealed carrier erythrocytes containing a recombinant…”
Get more information

A tryptophan-2-monooxygenase based amperometric biosensor for L-tryptophan determination: use of a competitive inhibitor as a tool for selectivity increase by Simonian, A.L, Rainina, E.I, Fitzpatrick, P.F, Wild, J.R

“…A new flow-injection amperometric biosensor based on immobilized tryptophan-2-monooxygenase (TMO) has been developed for reagentless L-tryptophan…”
Get full text

Investigation of stochastic fluctuations in the signal formation of microbiosensors by Arakelian, V.B., Wild, J.R., Simonian, A.L.

“…With a decrease in the dimensions of microbiosensors, the stochastic variation in the number of substrate complexes with the molecular recognition elements of…”
Get full text

Supporting doctors as healthcare quality and safety advocates: Recommendations from the Association of Surgeons in Training (ASiT) by Fleming, C.A., Humm, G., Wild, J.R., Mohan, H.M., Hornby, S.T., Harries, R.L., Fitzgerald, J.E.F., Beamish, A.J.

“…As front-line healthcare staff, doctors in surgical training occupy a unique organisational space rotating through hospitals and services in which they witness…”
Get full text

Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities by Reeves, T.E., Wales, M.E., Grimsley, J.K., Li, P., Cerasoli, D.M., Wild, J.R.

“…Rational site-directed mutagenesis and biophysical analyses have been used to explore the thermodynamic stability and catalytic capabilities of…”
Get full text

Biodegradation of chlorferon and diethylthiophosphate by consortia enriched from waste cattle dip solution by Ha, Jiyeon, Engler, Cady R., Wild, James R.

“…Chlorferon and diethylthiophosphate (DETP) are the hydrolysis products of coumaphos, an organophosphate pesticide. In this research, two consortia of bacterial…”
Get full text

FET-Based Biosensors for The Direct Detection of Organophosphate Neurotoxins by Simonian, A. L., Flounders, A. W., Wild, J. R.

“…Recent world‐wide terrorist events associated with the threat of hazardous chemical agent proliferation, and outbreaks of chemical contamination in the food…”
Get full text

Organophosphorus Hydrolase Is a Remarkably Stable Enzyme That Unfolds through a Homodimeric Intermediate by Grimsley, Janet K, Scholtz, J. Martin, Pace, C. Nick, Wild, James R

“…Organophosphorus hydrolase (OPH, EC 8.1.3.1) is a homodimeric enzyme that catalyzes the hydrolysis of organophosphorus pesticides and nerve agents. We have…”
Get full text

Erratum to “Discriminative detection of neurotoxins in multi-component samples” [Analytica Chimica Acta 444 (2001) 179–186] by Simonian, A.L, Efremenko, E.N, Wild, J.R

Get full text

Discriminative detection of neurotoxins in multi-component samples by Simonian, A.L, Efremenko, E.N, Wild, J.R

“…In order to develop a new strategy for the detection and discrimination of neurotoxins, the competing anti-acetylcholinesterase activities of mixtures of…”
Get full text

An enzyme based biosensor for the direct determination of diisopropyl fluorophosphate by Simonian, A.L, diSioudi, B.D, Wild, J.R

“…The ability of organophosphate hydrolase (OPH, EC 3.1.8.1) from Pseudomonas diminuta to hydrolyze diisopropyl fluorophosphate (DFP) was used to develop a…”
Get full text

Development of sensors for direct detection of organophosphates.: Part II: sol–gel modified field effect transistor with immobilized organophosphate hydrolase by Flounders, A.W, Singh, A.K, Volponi, J.V, Carichner, S.C, Wally, K, Simonian, A.S, Wild, J.R, Schoeniger, J.S

“…pH-sensitive field effect transistors (FET) were modified with organophosphate hydrolase (OPH) and used for direct detection of organophosphate compounds. OPH…”
Get full text

Bimetallic binding motifs in organophosphorus hydrolase are important for catalysis and structural organization by LAI, K, DAVE, K. I, WILD, J. R

“…Organophosphorus hydrolase is a broad spectrum phosphoric acid hydrolase (EC 3.1.8.1) which appears to contain a binuclear metal center with two metals…”
Get full text

Biotransformation patterns of 2,4,6-trinitrotoluene by aerobic bacteria by Kalafut, T, Wales, M E, Rastogi, V K, Naumova, R P, Zaripova, S K, Wild, J R

“…2,4,6-Trinitrotoluene (TNT), a toxic nitroaromatic explosive, accumulates in the environment, making necessary the remediation of contaminated areas and unused…”
Get full text

Development of sensors for direct detection of organophosphates by Flounders, A.W, Singh, A.K, Volponi, J.V, Carichner, S.C, Wally, K, Simonian, A.S, Wild, J.R, Schoeniger, J.S

Get full text

A New Approach For Discriminative Detection of Organophosphate Neurotoxins in the Presence of Other Cholinesterase Inhibitors by Simonian, A. L., Rainina, E. I., Wild, J. R.

“…A radically new approach for the discriminative determination of various neurotoxins has been developed. This novel biosensor combines a highly sensitive…”
Get full text