Search Results - "Wilcox, Stephen"

A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast by Pal, Bhupinder, Chen, Yunshun, Vaillant, François, Capaldo, Bianca D, Joyce, Rachel, Song, Xiaoyu, Bryant, Vanessa L, Penington, Jocelyn S, Di Stefano, Leon, Tubau Ribera, Nina, Wilcox, Stephen, Mann, Gregory B, Papenfuss, Anthony T, Lindeman, Geoffrey J, Smyth, Gordon K, Visvader, Jane E

“…To examine global changes in breast heterogeneity across different states, we determined the single‐cell transcriptomes of > 340,000 cells encompassing normal…”
Get full text

Assessment of spatial and temporal variability in the US solar resource from radiometric measurements and predictions from models using ground-based or satellite data by Gueymard, Christian A., Wilcox, Stephen M.

“…The US National Renewable Energy Laboratory (NREL) is responding to a growing demand for high-accuracy solar resource data with uncertainties significantly…”
Get full text

MYB orchestrates T cell exhaustion and response to checkpoint inhibition by Tsui, Carlson, Kretschmer, Lorenz, Rapelius, Svenja, Gabriel, Sarah S., Chisanga, David, Knöpper, Konrad, Utzschneider, Daniel T., Nüssing, Simone, Liao, Yang, Mason, Teisha, Torres, Santiago Valle, Wilcox, Stephen A., Kanev, Krystian, Jarosch, Sebastian, Leube, Justin, Nutt, Stephen L., Zehn, Dietmar, Parish, Ian A., Kastenmüller, Wolfgang, Shi, Wei, Buchholz, Veit R., Kallies, Axel

“…CD8 + T cells that respond to chronic viral infections or cancer are characterized by the expression of inhibitory receptors such as programmed cell death…”
Get full text

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease by Tye, Hazel, Yu, Chien-Hsiung, Simms, Lisa A., de Zoete, Marcel R., Kim, Man Lyang, Zakrzewski, Martha, Penington, Jocelyn S., Harapas, Cassandra R., Souza-Fonseca-Guimaraes, Fernando, Wockner, Leesa F., Preaudet, Adele, Mielke, Lisa A., Wilcox, Stephen A., Ogura, Yasunori, Corr, Sinead C., Kanojia, Komal, Kouremenos, Konstantinos A., De Souza, David P., McConville, Malcolm J., Flavell, Richard A., Gerlic, Motti, Kile, Benjamin T., Papenfuss, Anthony T., Putoczki, Tracy L., Radford-Smith, Graham L., Masters, Seth L.

“…Anti-microbial signaling pathways are normally triggered by innate immune receptors when detecting pathogenic microbes to provide protective immunity. Here we…”
Get full text

An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo by Aubrey, Brandon J., Kelly, Gemma L., Kueh, Andrew J., Brennan, Margs S., O’Connor, Liam, Milla, Liz, Wilcox, Stephen, Tai, Lin, Strasser, Andreas, Herold, Marco J.

“…The CRISPR/Cas9 technology enables the introduction of genomic alterations into almost any organism; however, systems for efficient and inducible gene…”
Get full text

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection by Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.

“…Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necroptosis, and apoptosis during…”
Get full text

Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling by Pal, Bhupinder, Chen, Yunshun, Vaillant, François, Jamieson, Paul, Gordon, Lavinia, Rios, Anne C., Wilcox, Stephen, Fu, Naiyang, Liu, Kevin He, Jackling, Felicity C., Davis, Melissa J., Lindeman, Geoffrey J., Smyth, Gordon K., Visvader, Jane E.

“…The mammary epithelium comprises two primary cellular lineages, but the degree of heterogeneity within these compartments and their lineage relationships…”
Get full text

Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections by Lerch, Anita, Koepfli, Cristian, Hofmann, Natalie E, Messerli, Camilla, Wilcox, Stephen, Kattenberg, Johanna H, Betuela, Inoni, O'Connor, Liam, Mueller, Ivo, Felger, Ingrid

“…Amplicon deep sequencing permits sensitive detection of minority clones and improves discriminatory power for genotyping multi-clone Plasmodium falciparum…”
Get full text

The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal by Yang, Yuqing, Kueh, Andrew J., Grant, Zoe L., Abeysekera, Waruni, Garnham, Alexandra L., Wilcox, Stephen, Hyland, Craig D., Di Rago, Ladina, Metcalf, Don, Alexander, Warren S., Coultas, Leigh, Smyth, Gordon K., Voss, Anne K., Thomas, Tim

“…The histone acetyltransferase HBO1 (MYST2, KAT7) is indispensable for postgastrulation development, histone H3 lysine 14 acetylation (H3K14Ac), and the…”
Get full text

How About a Theory of Direct Memory? by Wilcox, Stephen B.

Get full text

Comment From the Editor by Wilcox, Stephen B.

Get full text

Effects of iron supplements and iron-containing micronutrient powders on the gut microbiome in Bangladeshi infants: a randomized controlled trial by Baldi, Andrew, Braat, Sabine, Hasan, Mohammed Imrul, Bennett, Cavan, Barrios, Marilou, Jones, Naomi, Abdul Azeez, Imadh, Wilcox, Stephen, Roy, Pradip Kumar, Bhuiyan, Mohammad Saiful Alam, Ataide, Ricardo, Clucas, Danielle, Larson, Leila M., Hamadani, Jena, Zimmermann, Michael, Bowden, Rory, Jex, Aaron, Biggs, Beverley-Ann, Pasricha, Sant-Rayn

“…Anemia is highly prevalent globally, especially in young children in low-income countries, where it often overlaps with a high burden of diarrheal disease…”
Get full text

Chloroplast variation is incongruent with classification of the Australian bloodwood eucalypts (genus Corymbia, family Myrtaceae) by Schuster, Tanja M, Setaro, Sabrina D, Tibbits, Josquin F G, Batty, Erin L, Fowler, Rachael M, McLay, Todd G B, Wilcox, Stephen, Ades, Peter K, Bayly, Michael J

“…Previous molecular phylogenetic analyses have resolved the Australian bloodwood eucalypt genus Corymbia (~100 species) as either monophyletic or paraphyletic…”
Get full text

A novel metabarcoding diagnostic tool to explore protozoan haemoparasite diversity in mammals: a proof-of-concept study using canines from the tropics by Huggins, Lucas G., Koehler, Anson V., Ng-Nguyen, Dinh, Wilcox, Stephen, Schunack, Bettina, Inpankaew, Tawin, Traub, Rebecca J.

“…Haemoparasites are responsible for some of the most prevalent and debilitating canine illnesses across the globe, whilst also posing a significant zoonotic…”
Get full text

Community use of oral antibiotics transiently reprofiles the intestinal microbiome in young Bangladeshi children by Baldi, Andrew, Braat, Sabine, Imrul Hasan, Mohammed, Bennett, Cavan, Barrios, Marilou, Jones, Naomi, Moir-Meyer, Gemma, Abdul Azeez, Imadh, Wilcox, Stephen, Saiful Alam Bhuiyan, Mohammad, Ataide, Ricardo, Clucas, Danielle, Harrison, Leonard C., Arifeen, Shams El, Bowden, Rory, Biggs, Beverley-Ann, Jex, Aaron, Pasricha, Sant-Rayn

“…Antibiotics may alter the gut microbiome, and this is one of the mechanisms by which antimicrobial resistance may be promoted. Suboptimal antimicrobial…”
Get full text

Comment From the Editor by Wilcox, Stephen B.

Get full text

Human and viral membrane–associated E3 ubiquitin ligases MARCH1 and MIR2 recognize different features of CD86 to downregulate surface expression by Trenker, Raphael, Wu, Xinyu, Nguyen, Julie V., Wilcox, Stephen, Rubin, Alan F., Call, Matthew E., Call, Melissa J.

“…Immune-stimulatory ligands, such as major histocompatibility complex molecules and the T-cell costimulatory ligand CD86, are central to productive immunity…”
Get full text

Comment From the Editor by Wilcox, Stephen B.

Get full text

Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance by Deng, Yexuan, Diepstraten, Sarah T., Potts, Margaret A., Giner, Göknur, Trezise, Stephanie, Ng, Ashley P., Healey, Gerry, Kane, Serena R., Cooray, Amali, Behrens, Kira, Heidersbach, Amy, Kueh, Andrew J., Pal, Martin, Wilcox, Stephen, Tai, Lin, Alexander, Warren S., Visvader, Jane E., Nutt, Stephen L., Strasser, Andreas, Haley, Benjamin, Zhao, Quan, Kelly, Gemma L., Herold, Marco J.

“…CRISPR technologies have advanced cancer modelling in mice, but CRISPR activation (CRISPRa) methods have not been exploited in this context. We establish a…”
Get full text

Marked genetic diversity within Blastocystis in Australian wildlife revealed using a next generation sequencing–phylogenetic approach by Koehler, Anson V., Herath, H.M.P. Dilrukshi, Hall, Ross S., Wilcox, Stephen, Gasser, Robin B.

“…Blastocystis is a genus of intestinal stramenopiles that infect vertebrates, and may cause disease of the alimentary tract. Currently, at least 40 genotypes…”
Get full text