Search Results - "Wilcox, Sheri K."

From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay by Kraemer, Stephan, Vaught, Jonathan D, Bock, Christopher, Gold, Larry, Katilius, Evaldas, Keeney, Tracy R, Kim, Nancy, Saccomano, Nicholas A, Wilcox, Sheri K, Zichi, Dom, Sanders, Glenn M

“…Recently, we reported a SOMAmer-based, highly multiplexed assay for the purpose of biomarker identification. To enable seamless transition from highly…”
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Expanding the Chemistry of DNA for in Vitro Selection by Vaught, Jonathan D, Bock, Chris, Carter, Jeff, Fitzwater, Tim, Otis, Matt, Schneider, Dan, Rolando, Justin, Waugh, Sheela, Wilcox, Sheri K, Eaton, Bruce E

“…Six new 5-position modified dUTP derivatives connected by a unique amide linkage were synthesized and tested for compatibility with the enzymatic steps of in…”
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Protein signature of lung cancer tissues by Mehan, Michael R, Ayers, Deborah, Thirstrup, Derek, Xiong, Wei, Ostroff, Rachel M, Brody, Edward N, Walker, Jeffrey J, Gold, Larry, Jarvis, Thale C, Janjic, Nebojsa, Baird, Geoffrey S, Wilcox, Sheri K

“…Lung cancer remains the most common cause of cancer-related mortality. We applied a highly multiplexed proteomic technology (SOMAscan) to compare protein…”
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Genomic atlas of the human plasma proteome by Sun, Benjamin B., Maranville, Joseph C., Peters, James E., Stacey, David, Staley, James R., Blackshaw, James, Burgess, Stephen, Jiang, Tao, Paige, Ellie, Surendran, Praveen, Oliver-Williams, Clare, Kamat, Mihir A., Prins, Bram P., Wilcox, Sheri K., Zimmerman, Erik S., Chi, An, Bansal, Narinder, Spain, Sarah L., Wood, Angela M., Morrell, Nicholas W., Bradley, John R., Janjic, Nebojsa, Roberts, David J., Ouwehand, Willem H., Todd, John A., Soranzo, Nicole, Suhre, Karsten, Paul, Dirk S., Fox, Caroline S., Plenge, Robert M., Danesh, John, Runz, Heiko, Butterworth, Adam S.

“…Although plasma proteins have important roles in biological processes and are the direct targets of many drugs, the genetic factors that control…”
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Advances in human proteomics at high scale with the SOMAscan proteomics platform by Gold, Larry, Walker, Jeffrey J., Wilcox, Sheri K., Williams, Stephen

“…In 1997, while still working at NeXstar Pharmaceuticals, several of us made a proteomic bet. We thought then, and continue to think, that proteomics offers a…”
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Photoaptamer arrays applied to multiplexed proteomic analysis by Bock, Chris, Coleman, Mike, Collins, Brian, Davis, Jody, Foulds, Glenn, Gold, Larry, Greef, Chad, Heil, Jim, Heilig, Joseph S., Hicke, Brian, Nelson Hurst, Michele, Husar, Gregory M., Miller, Darcey, Ostroff, Rachel, Petach, Helen, Schneider, Dan, Vant-Hull, Barry, Waugh, Sheela, Weiss, Allison, Wilcox, Sheri K., Zichi, Dominic

“…Multiplexed photoaptamer‐based arrays that allow for the simultaneous measurement of multiple proteins of interest in serum samples are described. Since…”
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Aptamer-based multiplexed proteomic technology for biomarker discovery by Gold, Larry, Ayers, Deborah, Bertino, Jennifer, Bock, Christopher, Bock, Ashley, Brody, Edward N, Carter, Jeff, Dalby, Andrew B, Eaton, Bruce E, Fitzwater, Tim, Flather, Dylan, Forbes, Ashley, Foreman, Trudi, Fowler, Cate, Gawande, Bharat, Goss, Meredith, Gunn, Magda, Gupta, Shashi, Halladay, Dennis, Heil, Jim, Heilig, Joe, Hicke, Brian, Husar, Gregory, Janjic, Nebojsa, Jarvis, Thale, Jennings, Susan, Katilius, Evaldas, Keeney, Tracy R, Kim, Nancy, Koch, Tad H, Kraemer, Stephan, Kroiss, Luke, Le, Ngan, Levine, Daniel, Lindsey, Wes, Lollo, Bridget, Mayfield, Wes, Mehan, Mike, Mehler, Robert, Nelson, Sally K, Nelson, Michele, Nieuwlandt, Dan, Nikrad, Malti, Ochsner, Urs, Ostroff, Rachel M, Otis, Matt, Parker, Thomas, Pietrasiewicz, Steve, Resnicow, Daniel I, Rohloff, John, Sanders, Glenn, Sattin, Sarah, Schneider, Daniel, Singer, Britta, Stanton, Martin, Sterkel, Alana, Stewart, Alex, Stratford, Suzanne, Vaught, Jonathan D, Vrkljan, Mike, Walker, Jeffrey J, Watrobka, Mike, Waugh, Sheela, Weiss, Allison, Wilcox, Sheri K, Wolfson, Alexey, Wolk, Steven K, Zhang, Chi, Zichi, Dom

“…The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine. We…”
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Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin by Xie, Yang, Zamponi, Raffaella, Charlat, Olga, Ramones, Melissa, Swalley, Susanne, Jiang, Xiaomo, Rivera, Daniel, Tschantz, William, Lu, Bo, Quinn, Lisa, Dimitri, Chris, Parker, Jefferson, Jeffery, Doug, Wilcox, Sheri K, Watrobka, Mike, LeMotte, Peter, Granda, Brian, Porter, Jeffrey A, Myer, Vic E, Loew, Andreas, Cong, Feng

“…R‐spondin proteins sensitize cells to Wnt signalling and act as potent stem cell growth factors. Various membrane proteins have been proposed as potential…”
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Highly multiplexed proteomic platform for biomarker discovery, diagnostics, and therapeutics by Mehan, Michael R, Ostroff, Rachel, Wilcox, Sheri K, Steele, Fintan, Schneider, Daniel, Jarvis, Thale C, Baird, Geoffrey S, Gold, Larry, Janjic, Nebojsa

“…Progression from health to disease is accompanied by complex changes in protein expression in both the circulation and affected tissues. Large-scale…”
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Aptamers and the RNA world, past and present by Gold, Larry, Janjic, Nebojsa, Jarvis, Thale, Schneider, Dan, Walker, Jeffrey J, Wilcox, Sheri K, Zichi, Dom

“…Aptamers and the SELEX process were discovered over two decades ago. These discoveries have spawned a productive academic and commercial industry. The…”
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Single Ribosomal Protein Mutations in Antibiotic-Resistant Bacteria Analyzed by Mass Spectrometry by WILCOX, Sheri K, CAVEY, Gregory S, PEARSON, James D

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Rapid histochemistry using slow off-rate modified aptamers with anionic competition by Gupta, Shashi, Thirstrup, Derek, Jarvis, Thale C, Schneider, Daniel J, Wilcox, Sheri K, Carter, Jeff, Zhang, Chi, Gelinas, Amy, Weiss, Allison, Janjic, Nebojsa, Baird, Geoffrey S

“…Immunohistochemistry is used in both research and clinical settings to identify proteins in tissue samples. Despite the power and versatility of…”
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Replacement of the Axial Histidine Ligand with Imidazole in Cytochrome c Peroxidase. 2. Effects on Heme Coordination and Function by Hirst, Judy, Wilcox, Sheri K, Ai, Jingyuan, Moënne-Loccoz, Pierre, Loehr, Thomas M, Goodin, David B

“…The inability of imidazole to complement function in the axial histidine deletion mutant, H175G, of yeast cytochrome c peroxidase has been an intriguing but…”
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Replacement of the Axial Histidine Ligand with Imidazole in Cytochrome c Peroxidase. 1. Effects on Structure by Hirst, Judy, Wilcox, Sheri K, Williams, Pamela A, Blankenship, John, McRee, Duncan E, Goodin, David B

“…Replacement of the axial histidine ligand with exogenous imidazole has been accomplished in a number of heme protein mutants, where it often serves to…”
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Rational Design of a Functional Metalloenzyme:  Introduction of a Site for Manganese Binding and Oxidation into a Heme Peroxidase by Wilcox, Sheri K, Putnam, Christopher D, Sastry, Mallika, Blankenship, John, Chazin, Walter J, McRee, Duncan E, Goodin, David B

“…The design of a series of functionally active models for manganese peroxidase (MnP) is described. Artificial metal binding sites were created near the heme of…”
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Abstract 5305: Detection and quantification of proteins using protein identification by short-epitope mapping (PrISM) by Rinker, Torri, Egertson, Jarrett D., Tan, Steven, Ellahi, Aisha, Sherman, Jamie, Villancio-Wolter, Maria, Nortman, Brittany, Robinson, Julia, Dutta, Ahana, Winters, Katherine, Steiner, Noah, Ikwa, Elvis, Boyce, Hunter B., Joly, James H., Bartnicki, Filip, Indermühle, Pierre F., Inman, Christina, Paul, Shubhodeep, Villanueva, Jacinto, McGinnis, Jennifer, Sanford, Aimee A., Watts, Sophia, Nicastro, Jessica, Tonapi, Sonal S., Devine, Jacob, Li, Cara, Burke, Kaitlyn, Leano, Jonathan, Kondov, Nikola, Huber, Mirella, Ali, Bilal, Flores, Carlos, Wilcox, Sheri K., Mallick, Parag

“…Abstract Introduction: Here, we demonstrate Protein Identification by Short-epitope Mapping (PrISM), which aims to provide comprehensive proteome analysis with…”
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Protein conformer selection by ligand binding observed with crystallography by Cao, Yi, Musah, Rabi A., Wilcox, Sheri K., Goodin, David B., McRee, Duncan E.

“…A large‐scale movement between “closed” and “open” conformations of a protein loop was observed directly with protein crystallography by trapping individual…”
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Altering Substrate Specificity at the Heme Edge of Cytochrome c Peroxidase by Wilcox, Sheri K., Jensen, Gerard M., Fitzgerald, Melissa M., McRee, Duncan E., Goodin, David B.

“…Two mutants of cytochrome c peroxidase (CCP) are reported which exhibit unique specificities toward oxidation of small substrates. Ala-147 in CCP is located…”
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Alternative pathways for small molecule electron donors to cytochrome C peroxidase by Wilcox, Sheri K., Jensen, Gerard M., Fitzgerald, Melissa M., McRee, Duncan E., Goodin, David B.

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