Search Results - "Wilcox, Edward"

Highly accurate long reads are crucial for realizing the potential of biodiversity genomics by Hotaling, Scott, Wilcox, Edward R, Heckenhauer, Jacqueline, Stewart, Russell J, Frandsen, Paul B

“…Generating the most contiguous, accurate genome assemblies given available sequencing technologies is a long-standing challenge in genome science. With the…”
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Modifier variant of METTL13 suppresses human GAB1-associated profound deafness by Yousaf, Rizwan, Ahmed, Zubair M, Giese, Arnaud Pj, Morell, Robert J, Lagziel, Ayala, Dabdoub, Alain, Wilcox, Edward R, Riazuddin, Sheikh, Friedman, Thomas B, Riazuddin, Saima

“…A modifier variant can abrogate the risk of a monogenic disorder. DFNM1 is a locus on chromosome 1 encoding a dominant suppressor of human DFNB26 recessive,…”
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Heavy Ion and Proton-Induced Single Event Upset Characteristics of a 3-D NAND Flash Memory by Chen, Dakai, Wilcox, Edward, Ladbury, Raymond L., Seidleck, Christina, Kim, Hak, Phan, Anthony, LaBel, Kenneth A.

“…We evaluated the effects of heavy ion and proton irradiation for a 3-D NAND flash. The 3-D NAND showed similar single-event upset (SEU) sensitivity to a planar…”
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Observation of Low-Energy Proton Direct Ionization in a 72-Layer 3-D NAND Flash Memory by Wilcox, Edward P., Breeding, Matthew L., Casey, Megan C., Pellish, Jonathan A., Reed, Robert A., Alles, Michael L., Schrimpf, Ronald D.

“…Single-event upsets are observed in a 72-layer 3-D NAND flash memory operated in a single-level cell mode after low-energy proton (500 keV-1.2 MeV) and…”
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Single-Event Effects Response of 96- and 176-Layer 3D NAND Flash Memories by Wilcox, Edward P., Joplin, Matthew B., Berg, Melanie D.

“…Single-event effects testing (heavy-ion and proton) is presented for 96- and 176-layer commercially-available 3D NAND flash memory, with emphasis on SEFI…”
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Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction by Herbert, Zachary T, Kershner, Jamie P, Butty, Vincent L, Thimmapuram, Jyothi, Choudhari, Sulbha, Alekseyev, Yuriy O, Fan, Jun, Podnar, Jessica W, Wilcox, Edward, Gipson, Jenny, Gillaspy, Allison, Jepsen, Kristen, BonDurant, Sandra Splinter, Morris, Krystalynne, Berkeley, Maura, LeClerc, Ashley, Simpson, Stephen D, Sommerville, Gary, Grimmett, Leslie, Adams, Marie, Levine, Stuart S

“…Ribosomal RNA (rRNA) comprises at least 90% of total RNA extracted from mammalian tissue or cell line samples. Informative transcriptional profiling using…”
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A TID and SEE Characterization of Multi-Terabit COTS 3D NAND Flash by Wilcox, Edward P., Campola, Michael J.

“…Single-event effects and total ionizing dose testing are described for a 32-layer NAND flash memory, in both SLC and MLC configurations, with special…”
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Targeted amplicon sequencing (TAS): a scalable next-gen approach to multilocus, multitaxa phylogenetics by Bybee, Seth M, Bracken-Grissom, Heather, Haynes, Benjamin D, Hermansen, Russell A, Byers, Robert L, Clement, Mark J, Udall, Joshua A, Wilcox, Edward R, Crandall, Keith A

“…Next-gen sequencing technologies have revolutionized data collection in genetic studies and advanced genome biology to novel frontiers. However, to date,…”
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Single-Event Transient Case Study for System-Level Radiation Effects Analysis by Campola, Michael J., Austin, Rebekah A., Wilcox, Edward P., Kim, Hak S., Ladbury, Raymond L., Label, Kenneth A., Pellish, Jonathan A.

“…Analog single-event transient (SET) results are analyzed for two different applications within one system architecture. Application-specific analyses are…”
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The Tip-Link Antigen, a Protein Associated with the Transduction Complex of Sensory Hair Cells, Is Protocadherin-15 by Ahmed, Zubair M, Goodyear, Richard, Riazuddin, Saima, Lagziel, Ayala, Legan, P. Kevin, Behra, Martine, Burgess, Shawn M, Lilley, Kathryn S, Wilcox, Edward R, Riazuddin, Sheikh, Griffith, Andrew J, Frolenkov, Gregory I, Belyantseva, Inna A, Richardson, Guy P, Friedman, Thomas B

“…Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different…”
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Schottky Diode Derating for Survivability in a Heavy Ion Environment by Casey, Megan C., Lauenstein, Jean-Marie, Ladbury, Raymond L., Wilcox, Edward P., Topper, Alyson D., LaBel, Kenneth A.

“…In this paper, we irradiate a number of silicon power Schottky diodes from a variety of manufacturers. The tested diodes represent a wide assortment of reverse…”
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Mutations of the Protocadherin Gene PCDH15 Cause Usher Syndrome Type 1F by Ahmed, Zubair M., Riazuddin, Saima, Bernstein, Steve L., Ahmed, Zahoor, Khan, Shaheen, Griffith, Andrew J., Morell, Robert J., Friedman, Thomas B., Riazuddin, Sheikh, Wilcox, Edward R.

“…Human chromosome 10q21-22 harbors USH1F in a region of conserved synteny to mouse chromosome 10. This region of mouse chromosome 10 contains Pcdh15, encoding a…”
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Failure Analysis of Heavy Ion-Irradiated Schottky Diodes by Casey, Megan C., Lauenstein, Jean-Marie, Weachock, Ronald J., Wilcox, Edward P., Hua, Lang M., Campola, Michael J., Topper, Alyson D., Ladbury, Raymond L., LaBel, Kenneth A.

“…In this paper, we use high- and low-magnification optical microscope images, thermal infrared camera images, and scanning electron microscope images to…”
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Noncoding Mutations of HGF Are Associated with Nonsyndromic Hearing Loss, DFNB39 by Schultz, Julie M., Khan, Shaheen N., Ahmed, Zubair M., Riazuddin, Saima, Waryah, Ali M., Chhatre, Dhananjay, Starost, Matthew F., Ploplis, Barbara, Buckley, Stephanie, Velásquez, David, Kabra, Madhulika, Lee, Kwanghyuk, Hassan, Muhammad J., Ali, Ghazanfar, Ansar, Muhammad, Ghosh, Manju, Wilcox, Edward R., Ahmad, Wasim, Merlino, Glenn, Leal, Suzanne M., Riazuddin, Sheikh, Friedman, Thomas B., Morell, Robert J.

“…A gene causing autosomal-recessive, nonsyndromic hearing loss, DFNB39, was previously mapped to an 18 Mb interval on chromosome 7q11.22-q21.12. We mapped an…”
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PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23 by Ahmed, Zubair M., Riazuddin, Saima, Ahmad, Jamil, Bernstein, Steve L., Guo, Yan, Sabar, Muhammad F., Sieving, Paul, Riazuddin, Sheikh, Griffith, Andrew J., Friedman, Thomas B., Belyantseva, Inna A., Wilcox, Edward R.

“…Recessive splice site and nonsense mutations of PCDH15, encoding protocadherin 15, are known to cause deafness and retinitis pigmentosa in Usher syndrome type…”
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Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function by Riazuddin, Saima, Nazli, Sabiha, Ahmed, Zubair M, Yang, Yi, Zulfiqar, Fareeha, Shaikh, Rehan S, Zafar, Ahmed U, Khan, Shaheen N, Sabar, Farooq, Javid, Fouzia T, Wilcox, Edward R, Tsilou, Ekaterini, Boger, Erich T, Sellers, James R, Belyantseva, Inna A, Riazuddin, Sheikh, Friedman, Thomas B

“…Recessive mutations of MYO7A, encoding unconventional myosin VIIA, can cause either a deaf-blindness syndrome (type 1 Usher syndrome; USH1B) or nonsyndromic…”
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Mutations in the Gene Encoding Tight Junction Claudin-14 Cause Autosomal Recessive Deafness DFNB29 by Wilcox, Edward R, Burton, Quianna L, Naz, Sadaf, Riazuddin, Saima, Smith, Tenesha N, Ploplis, Barbara, Belyantseva, Inna, Ben-Yosef, Tamar, Liburd, Nikki A, Morell, Robert J, Kachar, Bechara, Wu, Doris K, Griffith, Andrew J, Riazuddin, Sheikh, Friedman, Thomas B

“…Tight junctions in the cochlear duct are thought to compartmentalize endolymph and provide structural support for the auditory neuroepithelium. The claudin…”
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NASA Goddard Space Flight Center's Current Radiation Effects Test Results by O'Bryan, Martha V., Wilcox, Edward P., Carstens, Thomas A., Ryder, Kaitlyn L., Barth, Jonathan D., Osheroff, Jason M., Ryder, Landen D., Casey, Megan C., Joplin, Matthew B., Lauenstein, Jean-Marie, LaBel, Kenneth A., Campola, Michael J., Wyrwas, Edward J., Antonsanti, Aubin P., Berg, Melanie D., Cochran, Donna J., Majewicz, Peter J., Pellish, Jonathan A.

“…We present results and analysis investigating the effects of radiation on a variety of candidate spacecraft electronics to heavy ion and proton induced single…”
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Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration by Ben-Yosef, Tamar, Belyantseva, Inna A., Saunders, Thomas L., Hughes, Elizabeth D., Kawamoto, Kohei, Van Itallie, Christina M., Beyer, Lisa A., Halsey, Kärin, Gardner, Donald J., Wilcox, Edward R., Rasmussen, Julia, Anderson, James M., Dolan, David F., Forge, Andrew, Raphael, Yehoash, Camper, Sally A., Friedman, Thomas B.

“…Tight junctions (TJs) create ion-selective paracellular permeability barriers between extracellular compartments. In the organ of Corti of the inner ear, TJs…”
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NASA Goddard Space Flight Center's Recent Radiation Effects Test Results by Topper, Alyson D., O'Bryan, Martha V., Wilcox, Edward P., Carstens, Thomas A., Barth, Jonathan D., Berg, Melanie, Casey, Megan C., Joplin, Matthew B., Lauenstein, Jean-Marie, Campola, Michael J., Cochran, Donna J., Pellish, Jonathan A., Majewicz, Peter J.

“…Total ionizing dose, displacement damage dose, and single event effects testing were performed to characterize and determine the suitability of candidate…”
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