Search Results - "Wiklendt, Lukasz"

Abnormal Perception of Urge to Defecate: An Important Pathophysiological Mechanism in Women With Chronic Constipation by Vollebregt, Paul F., Wiklendt, Lukasz, Burgell, Rebecca E., Chaichanavichkij, Pam, Dinning, Phil G., Knowles, Charles H., Scott, S. Mark

“…Although the association of absent or attenuated "call to stool" with constipation is well-recognized, no studies have systematically evaluated the perception…”
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Roles of three distinct neurogenic motor patterns during pellet propulsion in guinea‐pig distal colon by Costa, Marcello, Keightley, Lauren J., Wiklendt, Lukasz, Hibberd, Timothy J., Arkwright, John W., Omari, Taher, Wattchow, David A., Zagorodnyuk, Vladimir, Brookes, Simon J. H., Dinning, Phil G., Spencer, Nick J.

“…Key points Enteric neural circuits enable isolated preparations of guinea‐pig distal colon to propel solid and fluid contents by a self‐sustaining…”
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Sympathetic Pathways Target Cholinergic Neurons in the Human Colonic Myenteric Plexus by Parker, Dominic R, Wiklendt, Lukasz, Humenick, Adam, Chen, Bao Nan, Sia, Tiong Cheng, Wattchow, David A, Dinning, Phil G, Brookes, Simon J H

“…The sympathetic nervous system inhibits human colonic motility largely by effects on enteric neurons. Noradrenergic axons, which branch extensively in the…”
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Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice by Spencer, Nick J., Travis, Lee, Wiklendt, Lukasz, Costa, Marcello, Hibberd, Timothy J., Brookes, Simon J., Dinning, Phil, Hu, Hongzhen, Wattchow, David A., Sorensen, Julian

“…How the Enteric Nervous System (ENS) coordinates propulsion of content along the gastrointestinal (GI)-tract has been a major unresolved issue. We reveal a…”
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Automated Analysis Using a Bayesian Functional Mixed-Effects Model With Gaussian Process Responses for Wavelet Spectra of Spatiotemporal Colonic Manometry Signals by Wiklendt, Lukasz, Costa, Marcello, Scott, Mark S, Brookes, Simon J H, Dinning, Phil G

“…Manual analysis of human high-resolution colonic manometry data is time consuming, non-standardized and subject to laboratory bias. In this article we present…”
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Coexistent faecal incontinence and constipation: A cross-sectional study of 4027 adults undergoing specialist assessment by Vollebregt, Paul F., Wiklendt, Lukasz, Dinning, Phil G, Knowles, Charles H., Scott, S.Mark

“…In contrast to paediatric and geriatric populations, faecal incontinence and constipation in adults are generally considered separate entities. This may be…”
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Predicting the activation states of the muscles governing upper esophageal sphincter relaxation and opening by Omari, Taher I, Jones, Corinne A, Hammer, Michael J, Cock, Charles, Dinning, Philip, Wiklendt, Lukasz, Costa, Marcello, McCulloch, Timothy M

“…The swallowing muscles that influence upper esophageal sphincter (UES) opening are centrally controlled and modulated by sensory information. Activation and…”
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A Novel Method for Electrophysiological Analysis of EMG Signals Using MesaClip by Wiklendt, Lukasz, Brookes, Simon J. H., Costa, Marcello, Travis, Lee, Spencer, Nick J., Dinning, Phil G.

“…In electrophysiology, many methods have been proposed for the analysis of action potential firing frequencies. The aim of this study was to present an…”
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Neural mechanisms of peristalsis in the isolated rabbit distal colon: a neuromechanical loop hypothesis by Dinning, Phil G, Wiklendt, Lukasz, Omari, Taher, Arkwright, John W, Spencer, Nick J, Brookes, Simon J H, Costa, Marcello

“…Propulsive contractions of circular muscle are largely responsible for the movements of content along the digestive tract. Mechanical and electrophysiological…”
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Effects of Lactate on One Class of Group III (CT3) Muscle Afferents by Peterson, Rochelle A., König, Christine, Zimmermann, Katharina, Barry, Christine M., Wiklendt, Lukasz, Brookes, Simon J. H.

“…A class of Group III muscle afferent neurons has branching sensory terminals in connective tissue between layers of mouse abdominal muscles ("CT3 muscle…”
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Disengaging spinal afferent nerve communication with the brain in live mice by Kyloh, Melinda A., Hibberd, Timothy J., Castro, Joel, Harrington, Andrea M., Travis, Lee, Dodds, Kelsi N., Wiklendt, Lukasz, Brierley, Stuart M., Zagorodnyuk, Vladimir P., Spencer, Nick J.

“…Our understanding of how abdominal organs (like the gut) communicate with the brain, via sensory nerves, has been limited by a lack of techniques to…”
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808: ABNORMAL PERCEPTION OF URGE TO DEFECATE: AN IMPORTANT PATHOPHYSIOLOGICAL MECHANISM IN WOMEN WITH CONSTIPATION by Vollebregt, Paul, Wiklendt, Lukasz, Burgell, Rebecca, Chaichanavichkij, Pam, Dinning, Philip, Knowles, Charles, Scott, S. Mark

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Impact of exercise duration on gastrointestinal function and symptoms by Gaskell, Stephanie K, Burgell, Rebecca, Wiklendt, Lukasz, Dinning, Phil G, Costa, Ricardo J S

“…The study aimed to determine the impact of exercise duration on gastrointestinal functional responses and gastrointestinal symptoms (GISs) in response to…”
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Tu1385: INHIBITED POSTPRANDIAL RETROGRADE CYCLIC MOTOR PATTERN IN RECTO-SIGMOID COLON OF PATIENTS WITH DIARRHEA PREDOMINANT IRRITABLE BOWEL SYNDROME by Dinning, Philip, Rosli, Reizal Mohd, Paskaranandavadivel, Nira, Costa, Marcello, Brookes, Simon J., Grady, Gregory O, Wiklendt, Lukasz

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Abnormal perception of urge to defecate: an important pathophysiological mechanism in women with chronic constipation by Vollebregt, Paul F, Wiklendt, Lukasz, Burgell, Rebecca E, Chaichanavichkij, Pam, Dinning, Phil G, Knowles, Charles H, Scott, S Mark

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Su1591 Cross-Wavelet Transform for the Automated Analysis of High-Resolution Colonic Manometry Data by Wiklendt, Lukasz, Costa, Marcello, Dinning, Philip

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Su1617 INFLUENCE OF COLONIC CONTENT UPON HIGH RESOLUTION COLONIC MANOMETRY RECORDINGS by Wiklendt, Lukasz, Wilkinson-Smith, Victoria, Scott, S. Mark, Sansone, Stefano, Zdanavciene, Austra, Knowles, Charles, Corsetti, Maura, Marciani, Luca, Spiller, Robin C., Dinning, Philip

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Identification of a Rhythmic Firing Pattern in the Enteric Nervous System That Generates Rhythmic Electrical Activity in Smooth Muscle by Spencer, Nick J, Hibberd, Timothy J, Travis, Lee, Wiklendt, Lukasz, Costa, Marcello, Hu, Hongzhen, Brookes, Simon J, Wattchow, David A, Dinning, Phil G, Keating, Damien J, Sorensen, Julian

“…The enteric nervous system (ENS) contains millions of neurons essential for organization of motor behavior of the intestine. It is well established that the…”
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Does exertional heat stress impact gastrointestinal function and symptoms? by Gaskell, Stephanie K., Burgell, Rebecca, Wiklendt, Lukasz, Dinning, Phil, Costa, Ricardo J.S.

“…Exertional-heat stress generates a thermoregulatory strain that exacerbates splanchnic hypoperfusion and sympathetic drive, but the effects on gastrointestinal…”
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Manometric demonstration of duodenal/jejunal motor function consistent with the duodenal brake mechanism by Dent, John, Deloose, Eveline, Dinning, Philip, Corsetti, Maura, Rommel, Nathalie, Tack, Jan, Wiklendt, Lukasz, Papageorgiou, Anthony William, Arkwright, John William

“…Background High‐resolution manometric studies below the stomach are rare due to technical limitations of traditional manometry catheters. Consequently,…”
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