Search Results - "Wikel, Stephen K"

Ticks and Tick-Borne Infections: Complex Ecology, Agents, and Host Interactions by Wikel, Stephen K

“…Ticks transmit the most diverse array of infectious agents of any arthropod vector. Both ticks and the microbes they transmit are recognized as significant…”
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Resistance to Ticks and the Path to Anti-Tick and Transmission Blocking Vaccines by van Oosterwijk, Jolieke G, Wikel, Stephen K

“…The medical and veterinary public health importance of ticks and tick-borne pathogens is increasing due to the expansion of the geographic ranges of both ticks…”
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An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti by Ribeiro, José M C, Arcà, Bruno, Lombardo, Fabrizio, Calvo, Eric, Phan, Van My, Chandra, Prafulla K, Wikel, Stephen K

“…Saliva of blood-sucking arthropods contains a cocktail of antihemostatic agents and immunomodulators that help blood feeding. Mosquitoes additionally feed on…”
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An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks by Ribeiro, José M.C., Alarcon-Chaidez, Francisco, B. Francischetti, Ivo M., Mans, Ben J., Mather, Thomas N., Valenzuela, Jesus G., Wikel, Stephen K.

“…Over 8000 expressed sequence tags from six different salivary gland cDNA libraries from the tick Ixodes scapularis were analyzed. These libraries derive from…”
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Tick-host-pathogen systems immunobiology: an interactive trio by Wikel, Stephen K

“…Significant new insights are being made into tick modulation of host immune defenses and the implications of those host defense changes on tick-borne pathogen…”
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Ixodes scapularis saliva mitigates inflammatory cytokine secretion during Anaplasma phagocytophilum stimulation of immune cells by Chen, Gang, Severo, Maiara S, Sohail, Mohammad, Sakhon, Olivia S, Wikel, Stephen K, Kotsyfakis, Michail, Pedra, Joao HF

“…BACKGROUND: Ixodes scapularis saliva enables the transmission of infectious agents to the mammalian host due to its immunomodulatory, anesthetic and…”
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Differential expression of Aedes aegypti salivary transcriptome upon blood feeding by Thangamani, Saravanan, Wikel, Stephen K

“…Saliva of Aedes aegypti contains a complex array of proteins essential for both blood feeding and pathogen transmission. A large numbers of those proteins are…”
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Transcriptional profiling of the murine cutaneous response during initial and subsequent infestations with Ixodes scapularis nymphs by Heinze, Dar M, Wikel, Stephen K, Thangamani, Saravanan, Alarcon-Chaidez, Francisco J

“…BACKGROUND: Ixodes scapularis ticks are hematophagous arthropods capable of transmitting many infectious agents to humans. The process of blood feeding is an…”
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Tick modulation of host immunity: an important factor in pathogen transmission by Wikel, Stephen K

“…Immunological interactions at the tick–host interface involve innate and specific acquired host immune defenses and immunomodulatory countermeasures by the…”
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Zoonoses: Changing, Challenging, and Increasing Global Disease Threats by Wikel, Stephen K.

“…The public awareness of zoonotic pathogens as well as the threats they pose to global public health have grown significantly, since the emergence of…”
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Amblyomma imitator ticks as vectors of Rickettsia rickettsii, Mexico by Oliveira, Karla A, Pinter, Adriano, Medina-Sanchez, Aaron, Boppana, Venkata D, Wikel, Stephen K, Saito, Tais B, Shelite, Thomas, Blanton, Lucas, Popov, Vsevolod, Teel, Pete D, Walker, David H, Galvao, Marcio A M, Mafra, Claudio, Bouyer, Donald H

“…Real-time PCR of Amblyomma imitator tick egg masses obtained in Nuevo Leon State, Mexico, identified a Rickettsia species. Sequence analyses of 17-kD common…”
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Hypersensitivity to ticks and Lyme disease risk by Burke, Georgine, Wikel, Stephen K, Spielman, Andrew, Telford, Sam R, McKay, Kathleen, Krause, Peter J

“…Although residents of Lyme disease-endemic regions describe frequent exposure to ticks, Lyme disease develops in relatively few. To determine whether people…”
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Rhipicephalus microplus salivary gland molecules induce differential CD86 expression in murine macrophages by Brake, Danett K, Wikel, Stephen K, Tidwell, Jason P, Pérez de León, Adalberto A

“…Tick parasitism is a major impediment for cattle production in many parts of the world. The southern cattle tick, Rhipicephalus (Boophilus) microplus, is an…”
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Regulation of OspE-Related, OspF-Related, and Elp Lipoproteins of Borrelia burgdorferi Strain 297 by Mammalian Host-Specific Signals by HEFTY, P. Scott, JOLLIFF, Sarah E, CAIMANO, Melissa J, WIKEL, Stephen K, RADOLF, Justin D, AKINS, Darrin R

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Changes in Temporal and Spatial Patterns of Outer Surface Lipoprotein Expression Generate Population Heterogeneity and Antigenic Diversity in the Lyme Disease Spirochete, Borrelia burgdorferi by HEFTY, P. Scott, JOLLIFF, Sarah E, CAIMANO, Melissa J, WIKEL, Stephen K, AKINS, Darrin R

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Blood feeding by the Rocky Mountain spotted fever vector, Dermacentor andersoni, induces interleukin-4 expression by cognate antigen responding CD4+ T cells by Boppana, Venkata D, Thangamani, Saravanan, Alarcon-Chaidez, Francisco J, Adler, Adam J, Wikel, Stephen K

“…Tick modulation of host defenses facilitates both blood feeding and pathogen transmission. Several tick species deviate host T cell responses toward a Th2…”
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Field evaluation of a novel oral reservoir-targeted vaccine against Borrelia burgdorferi utilizing an inactivated whole-cell bacterial antigen expression vehicle by Stafford, Kirby C., Williams, Scott C., van Oosterwijk, Jolieke G., Linske, Megan A., Zatechka, Steve, Richer, Luciana M., Molaei, Goudarz, Przybyszewski, Chris, Wikel, Stephen K.

“…Blacklegged ticks ( Ixodes scapularis ) are the principal vector for Borrelia burgdorferi, among other infectious agents, in the northeastern, mid-Atlantic,…”
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Administration of an Orally Delivered Substrate Targeting a Mammalian Zoonotic Pathogen Reservoir Population: Novel Application and Biomarker Analysis by Williams, Scott C, van Oosterwijk, Jolieke G, Linske, Megan A, Zatechka, Steve, Richer, Luciana M, Przybyszewski, Chris, Wikel, Stephen K, Stafford, , III, Kirby C

“…Reservoir-targeted vaccines (RTVs) have the potential to be effective at breaking the transmission cycle of many tick-borne pathogens including, but not…”
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OspE-Related, OspF-Related, and Elp Lipoproteins Are Immunogenic in Baboons Experimentally Infected with Borrelia burgdorferi and in Human Lyme Disease Patients by HEFTY, P. Scott, BROOKS, Chad S, JETT, Amy M, WHITE, Gary L, WIKEL, Stephen K, KENNEDY, Ronald C, AKINS, Darrin R

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Cellular Immunity, but Not Gamma Interferon, Is Essential for Resolution of Babesia microti Infection in BALB/c Mice by CLAWSON, Michael L, PACIORKOWSKI, Natalia, RAJAN, T. V, LA VAKE, Carson, POPE, Conny, LA VAKE, Morgan, WIKEL, Stephen K, KRAUSE, Peter J, RADOLF, Justin D

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