Search Results - "Wik, Elin"
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Brain pharmacokinetics of mono- and bispecific amyloid-β antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis
Published in Fluids and barriers of the CNS (12-12-2022)“…Treatment with amyloid-β (Aβ) targeting antibodies is a promising approach to remove Aβ brain pathology in Alzheimer's disease (AD) and possibly even slow down…”
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Journal Article -
2
Long-term effects of immunotherapy with a brain penetrating Aβ antibody in a mouse model of Alzheimer's disease
Published in Alzheimer's research & therapy (02-05-2023)“…Brain-directed immunotherapy is a promising strategy to target amyloid-β (Aβ) deposits in Alzheimer's disease (AD). In the present study, we compared the…”
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Journal Article -
3
Antibody engagement with amyloid-beta does not inhibit 11CPiB binding for PET imaging
Published in Journal of neurochemistry (01-09-2024)“…The elimination of amyloid-beta (Aβ) plaques in Alzheimer's disease patients after treatment with anti-Aβ antibodies such as lecanemab and aducanumab is…”
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4
Antibody engagement with amyloid‐beta does not inhibit [11C]PiB binding for PET imaging
Published in Journal of neurochemistry (01-09-2024)“…The elimination of amyloid‐beta (Aβ) plaques in Alzheimer's disease patients after treatment with anti‐Aβ antibodies such as lecanemab and aducanumab is…”
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Journal Article -
5
Brain pharmacokinetics of mono- and bispecific amyloid-[beta] antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis
Published in Fluids and barriers of the CNS (12-12-2022)“…Background Treatment with amyloid-[beta] (A[beta]) targeting antibodies is a promising approach to remove A[beta] brain pathology in Alzheimer's disease (AD)…”
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Journal Article -
6
Long-term effects of immunotherapy with a brain penetrating A[beta] antibody in a mouse model of Alzheimer's disease
Published in Alzheimer's research & therapy (02-05-2023)“…Background Brain-directed immunotherapy is a promising strategy to target amyloid-[beta] (A[beta]) deposits in Alzheimer's disease (AD). In the present study,…”
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Journal Article