Search Results - "Wijngaard, René M"

Intestinal Fungal Dysbiosis Is Associated With Visceral Hypersensitivity in Patients With Irritable Bowel Syndrome and Rats by Botschuijver, Sara, Roeselers, Guus, Levin, Evgeni, Jonkers, Daisy M., Welting, Olaf, Heinsbroek, Sigrid E.M., de Weerd, Heleen H., Boekhout, Teun, Fornai, Matteo, Masclee, Ad A., Schuren, Frank H.J., de Jonge, Wouter J., Seppen, Jurgen, van den Wijngaard, René M.

“…Visceral hypersensitivity is one feature of irritable bowel syndrome (IBS). Bacterial dysbiosis might be involved in the activation of nociceptive sensory…”
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Rhamnogalacturonan, a chemically-defined polysaccharide, improves intestinal barrier function in DSS-induced colitis in mice and human Caco-2 cells by Maria-Ferreira, Daniele, Nascimento, Adamara Machado, Cipriani, Thales Ricardo, Santana-Filho, Arquimedes Paixão, Watanabe, Paulo da Silva, Sant´Ana, Debora de Mello Gonçales, Luciano, Fernando Bittencourt, Bocate, Karla Carolina Paiva, van den Wijngaard, René M., Werner, Maria Fernanda de Paula, Baggio, Cristiane Hatsuko

“…Natural polysaccharides have emerged as an important class of bioactive compounds due their beneficial biological effects. Here we investigated the protective…”
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Abnormal Responses to Local Esophageal Food Allergen Injections in Adult Patients With Eosinophilic Esophagitis by Warners, Marijn J., Terreehorst, Ingrid, van den Wijngaard, René M., Akkerdaas, Jaap, van Esch, Betty C.A.M., van Ree, Ronald, Versteeg, Serge A., Smout, Andreas J.P.M., Bredenoord, Albert J.

“…Skin tests and measurement of serum levels of immunoglobulin E do not accurately identify foods for elimination from the diets of patients with eosinophilic…”
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Ziverel for PPI-refractory reflux symptoms: efficacy and mechanisms of action in humans by Kuipers, Thijs, Oude Nijhuis, Renske A B, van den Wijngaard, René M, Oors, Jac M, Smout, André J P M, Bredenoord, Albert J

“…It is thought that esophageal hypersensitivity in combination with an impaired mucosal barrier function contributes to PPI-resistant reflux symptoms. Ziverel,…”
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Candida spp. in Human Intestinal Health and Disease: More than a Gut Feeling by Kreulen, Irini A. M., de Jonge, Wouter J., van den Wijngaard, René M., van Thiel, Isabelle A. M.

“…Fungi are an essential part of the normal collection of intestinal microorganisms, even though their collective abundance comprises only 0.1–1% of all fecal…”
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Acetylcholine-producing T cells in the intestine regulate antimicrobial peptide expression and microbial diversity by Dhawan, Shobhit, De Palma, Giada, Willemze, Rose A, Hilbers, Francisca W, Verseijden, Caroline, Luyer, Misha D, Nuding, Sabine, Wehkamp, Jan, Souwer, Yuri, de Jong, Esther C, Seppen, J, van den Wijngaard, René M, Wehner, Sven, Verdu, Elena, Bercik, Premek, de Jonge, Wouter J

“…The cholinergic anti-inflammatory pathway reduces systemic tumor necrosis factor (TNF) via acetylcholine-producing memory T cells in the spleen. These choline…”
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Relevance of mast cell–nerve interactions in intestinal nociception by van Diest, Sophie A., Stanisor, Oana I., Boeckxstaens, Guy E., de Jonge, Wouter J., van den Wijngaard, René M.

“…Cross-talk between the immune- and nervous-system is considered an important biological process in health and disease. Because mast cells are often…”
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Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms by Botschuijver, Sara, van Diest, Sophie A., van Thiel, Isabelle A. M., Saia, Rafael S., Strik, Anne S., Yu, Zhumei, Maria-Ferreira, Daniele, Welting, Olaf, Keszthelyi, Daniel, Jennings, Gary, Heinsbroek, Sigrid E. M., Elferink, Ronald P. Oude, Schuren, Frank H. J., de Jonge, Wouter J., van den Wijngaard, René M.

“…Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal…”
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Genetic and phenotypic diversity of fecal Candida albicans strains in irritable bowel syndrome by van Thiel, Isabelle A. M., Stavrou, Aimilia A., de Jong, Auke, Theelen, Bart, Davids, Mark, Hakvoort, Theodorus B. M., Admiraal-van den Berg, Iris, Weert, Isabelle C. M., de Kruijs, Martine A. M. Hesselink-van, Vu, Duong, Moissl-Eichinger, Christine, Heinsbroek, Sigrid E. M., Jonkers, Daisy M. A. E., Hagen, Ferry, Boekhout, Teun, de Jonge, Wouter J., van den Wijngaard, René M.

“…Irritable bowel syndrome (IBS) is a common disorder characterized by chronic abdominal pain and changes in bowel movements. Visceral hypersensitivity is…”
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Dietary Curdlan Enhances Bifidobacteria and Reduces Intestinal Inflammation in Mice by Rahman, Shafaque, Davids, Mark, van Hamersveld, Patricia H P, Welting, Olaf, Rahaoui, Hakim, Schuren, Frank, Meijer, Sybren L, van den Wijngaard, René M, Hakvoort, Theodorus B M, de Jonge, Wouter J, Heinsbroek, Sigrid E M

“…β-glucan consumption is known for its beneficial health effects, but the mode of action is unclear. While humans and mice lack the required enzymes to digest…”
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Fecal Filobasidium Is Associated with Clinical Remission and Endoscopic Response following Fecal Microbiota Transplantation in Mild-to-Moderate Ulcerative Colitis by van Thiel, Isabelle A M, Rahman, Shafaque, Hakvoort, Theodorus B M, Davids, Mark, Verseijden, Caroline, van Hamersveld, Patricia H P, Bénard, Mèlanie V, Lodders, Maarten H, Boekhout, Teun, van den Wijngaard, René M, Heinsbroek, Sigrid E M, Ponsioen, Cyriel Y, de Jonge, Wouter J

“…Fecal microbiota transplantation (FMT) has the potential to restore (bacterial and fungal) microbial imbalance in ulcerative colitis (UC) patients and…”
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Mucosal integrity and sensitivity to acid in the proximal esophagus in patients with gastroesophageal reflux disease by van Hoeij, Froukje B, Weijenborg, Pim W, van den Bergh Weerman, Marius A, van den Wijngaard, René M J G J, Verheij, J, Smout, André J P M, Bredenoord, Albert J

“…Acid reflux episodes that extend to the proximal esophagus are more likely to be perceived. This suggests that the proximal esophagus is more sensitive to acid…”
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The Role of Mast Cell Stabilization in Treatment of Postoperative Ileus: A Pilot Study by The, Frans O, Buist, Marrije R, Lei, Aaltje, Bennink, Roelof J, Hofland, Jan, van den Wijngaard, René M, de Jonge, Wouter J, Boeckxstaens, Guy E

“…Although postoperative ileus (POI) is considered multifactorial, intestinal inflammation resulting from manipulation-induced mast cell activation is recognized…”
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Dietary Marine n-3 PUFAs Do Not Affect Stress-Induced Visceral Hypersensitivity in a Rat Maternal Separation Model by van Diest, Sophie A, van den Elsen, Lieke W J, Klok, Allison J, Welting, Olaf, Hilbers, Francisca W, van de Heijning, Bert J, Gaemers, Ingrid C, Boeckxstaens, Guy E, Werner, Maria F, Willemsen, Linette E M, de Jonge, Wouter J, van den Wijngaard, René M

“…Although never evaluated for efficacy, n-3 (ω-3) long-chain polyunsaturated fatty acids (LCPUFAs) are commercially offered as treatment for irritable bowel…”
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Peripheral relays in stress-induced activation of visceral afferents in the gut by van den Wijngaard, René M, Klooker, Tamira K, de Jonge, Wouter J, Boeckxstaens, Guy E

“…Abstract Multiple organs are targeted by the stress response, but the focus of this article is on stress-induced activation of visceral afferents in the gut…”
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Neuropeptide receptors in intestinal disease: physiology and therapeutic potential by Snoek, Susanne A, Borensztajn, Keren S, van den Wijngaard, René M, de Jonge, Wouter J

“…The autonomous nervous system of the gut is increasingly recognized as an important regulatory factor in intestinal permeability and immune cell activation…”
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Proton Pump Inhibitors Partially Restore Mucosal Integrity in Patients With Proton Pump Inhibitor–Responsive Esophageal Eosinophilia but Not Eosinophilic Esophagitis by van Rhijn, Bram D, Weijenborg, Pim W, Verheij, Joanne, van den Bergh Weerman, Marius A, Verseijden, Caroline, van den Wijngaard, René M.J.G.J, de Jonge, Wouter J, Smout, Andreas J.P.M, Bredenoord, Albert J

“…Background & Aims Histologic analysis is used to distinguish patients with proton pump inhibitor–responsive eosinophilia (PPI-REE) from those with eosinophilic…”
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Histological Response to Fluticasone Propionate in Patients With Eosinophilic Esophagitis Is Associated With Improved Functional Esophageal Mucosal Integrity by van Rhijn, Bram D, Verheij, Joanne, van den Bergh Weerman, Marius A, Verseijden, Caroline, van den Wijngaard, René M J G J, de Jonge, Wouter J, Smout, Andreas J P M, Bredenoord, Albert J

“…The esophageal mucosal integrity is impaired in patients with eosinophilic esophagitis (EoE). We aimed to evaluate the effect of fluticasone propionate on…”
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Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice by de Jonge, Wouter J, The, Frans O, van der Coelen, Dennis, Bennink, Roelof J, Reitsma, Pieter H, van Deventer, Sander J, van den Wijngaard, René M, Boeckxstaens, Guy E

“…Inflammation of the intestinal muscularis following manipulation during surgery plays a crucial role in the pathogenesis of postoperative ileus. Here, we…”
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Achalasia: From New Insights in Pathophysiology to Treatment by Boeckxstaens, Guy E, De Jonge, Wouter, Wijngaard, René M, Benninga, Marc A

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