Search Results - "Wijewardana, Viskam"
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Editorial: Irradiation technologies for vaccine development
Published in Frontiers in immunology (09-01-2023)Get full text
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Development of a vaccine based on bacteria‐mimicking tumor cells coated with novel engineered toll‐like receptor 2 ligands
Published in Cancer science (01-05-2018)“…For a successful tumor vaccine, it is necessary to develop effective immuno‐adjuvants and identify specific tumor antigens. Tumor cells obtained from surgical…”
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Different Neutralizing Antibody Responses of Heterologous Sera on Sheeppox and Lumpy Skin Disease Viruses
Published in Viruses (01-07-2024)“…Sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV) are the three members of the genus within the family and are the etiologic…”
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Evaluation of Immune Responses and Histopathological Effects against Gamma Irradiated Avian Influenza (Sub type H9N2) Vaccine on Broiler Chicken
Published in Brazilian Archives of Biology and Technology (01-01-2020)“…Abstract Vaccination is a good strategy for the prevention of avian influenza virus. In this research Gamma Irradiated Avian Influenza (Sub type H9N2) Vaccine…”
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African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity
Published in PLoS pathogens (02-03-2020)“…Unlike HIV infection, SIV infection is generally nonpathogenic in natural hosts, such as African green monkeys (AGMs), despite life-long high viral…”
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Vaccination With a Gamma Irradiation-Inactivated African Swine Fever Virus Is Safe But Does Not Protect Against a Challenge
Published in Frontiers in immunology (26-04-2022)“…African swine fever (ASF) is among the most devastating viral diseases of pigs and wild boar worldwide. In recent years, the disease has spread alarmingly…”
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Gamma-Irradiated Fowl Cholera Mucosal Vaccine: Potential Vaccine Candidate for Safe and Effective Immunization of Chicken Against Fowl Cholera
Published in Frontiers in immunology (30-11-2021)“…Fowl cholera (FC) caused by is among the serious infectious diseases of poultry. Currently, formalin inactivated FC (FI-FC) vaccine is widely used in Ethiopia…”
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Mucosal Immunity of Major Gastrointestinal Nematode Infections in Small Ruminants Can Be Harnessed to Develop New Prevention Strategies
Published in International journal of molecular sciences (01-02-2024)“…Gastrointestinal parasitic nematode (GIN) infections are the cause of severe losses to farmers in countries where small ruminants such as sheep and goat are…”
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Aerosol vaccination of chicken pullets with irradiated avian pathogenic Escherichia coli induces a local immunostimulatory effect
Published in Frontiers in immunology (16-05-2023)“…The present study investigated the expression of cytokines and cellular changes in chickens following vaccination with irradiated avian pathogenic (APEC)…”
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SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations
Published in PLoS pathogens (01-01-2013)“…Pathogenesis studies of SIV infection have not been performed to date in wild monkeys due to difficulty in collecting and storing samples on site and the lack…”
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Rapid influx and death of plasmacytoid dendritic cells in lymph nodes mediate depletion in acute simian immunodeficiency virus infection
Published in PLoS pathogens (01-05-2009)“…Plasmacytoid dendritic cells (pDC) are essential innate immune system cells that are lost from the circulation in human immunodeficiency virus (HIV)-infected…”
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Low Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Molecular Changes That Occur to Repair Radiation Damage and Gene Transcripts That May Be Involved in Establishing Disease in Mice Post-Irradiation
Published in Frontiers in immunology (13-05-2022)“…The protozoan parasite is responsible for causing surra in a variety of mammalian hosts and is spread by many vectors over a wide geographical area making it…”
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Innate Immune Responses to Wildtype and Attenuated Sheeppox Virus Mediated Through RIG-1 Sensing in PBMC In-Vitro
Published in Frontiers in immunology (15-06-2021)“…Sheeppox (SPP) is a highly contagious disease of small ruminants caused by sheeppox virus (SPPV) and predominantly occurs in Asia and Africa with significant…”
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Carboxymethyl chitosan bounded iron oxide nanoparticles and gamma‐irradiated avian influenza subtype H9N2 vaccine to development of immunity on mouse and chicken
Published in Veterinary medicine and science (01-03-2022)“…Background Avian influenza virus (AIV) subtype H9N2 is a low pathogenic avian influenza virus (LPAIV). Objective This study aims to evaluate the humoral and…”
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Development of effective tumor immunotherapy using a novel dendritic cell-targeting Toll-like receptor ligand
Published in PloS one (30-11-2017)“…Although dendritic cell (DC)-based immunotherapy shows little toxicity, improvements should be necessary to obtain satisfactory clinical outcome. Using…”
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Preliminary screening of the aqueous extracts of twenty-three different seaweed species in Sri Lanka with in-vitro and in-vivo assays
Published in Heliyon (01-06-2020)“…Seaweeds are an important source of bioactive compounds which are applied in various aspects of medicinal investigations. The present study was conducted to…”
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Effect of ovarian hormones on maturation of dendritic cells from peripheral blood monocytes in dogs
Published in Journal of Veterinary Medical Science (01-07-2015)“…Previously, we reported that ovarian hormones affect the immune response against E. coli isolated from the dogs affected with pyometra. In order to investigate…”
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Irradiated Non-replicative Lactic Acid Bacteria Preserve Metabolic Activity While Exhibiting Diverse Immune Modulation
Published in Frontiers in veterinary science (18-05-2022)“…In the recent years, safety concerns regarding the administration of probiotics led to an increased interest in developing inactivated probiotics, also called…”
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Protective Efficacy of H9N2 Avian Influenza Vaccines Inactivated by Ionizing Radiation Methods Administered by the Parenteral or Mucosal Routes
Published in Frontiers in veterinary science (11-07-2022)“…H9N2 viruses have become, over the last 20 years, one of the most diffused poultry pathogens and have reached a level of endemicity in several countries…”
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Generation of functional platelets from canine induced pluripotent stem cells
Published in Stem cells and development (15-07-2013)“…Thrombocytopenia (TTP) is a blood disease common to canines and human beings. Currently, there is no valid therapy for this disease except blood transfusion…”
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