Search Results - "Wijesuriya, Suranga J"
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Glycosylation and the activation of proteinase‐activated receptor 2 (PAR2) by human mast cell tryptase
Published in British journal of pharmacology (01-10-2001)“…Human mast cell tryptase appears to display considerable variation in activating proteinase‐activated receptor 2 (PAR2). We found tryptase to be an inefficient…”
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Modified proteinase-activated receptor-1 and -2 derived peptides inhibit proteinase-activated receptor-2 activation by trypsin
Published in The Journal of pharmacology and experimental therapeutics (01-02-2002)“…Trypsin activates proteinase-activated receptor-2 (PAR(2)) by a mechanism that involves the release of a tethered receptor-activating sequence. We have…”
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Proteinase-activated receptor 2: differential activation of the receptor by tethered ligand and soluble peptide analogs
Published in The Journal of pharmacology and experimental therapeutics (01-09-2002)“…Activation of rat proteinase-activated receptor 2 (PAR2) by trypsin involves the unmasking of the tethered sequence S(37)LIGRL(42) that either tethered or on…”
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Glycosylation of human proteinase-activated receptor-2 (hPAR2): role in cell surface expression and signalling
Published in Biochemical journal (01-12-2002)“…We have analysed the role of N-linked glycosylation in regulating human proteinase-activated receptor-2 (hPAR(2)) expression and function. Epitope-tagged…”
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Up-regulation and Activation of Proteinase-Activated Receptor 2 in Early and Delayed Radiation Injury in the Rat Intestine: Influence of Biological Activators of Proteinase-Activated Receptor 2
Published in Radiation research (01-11-2003)“…Wang, J., Zheng, H., Hollenberg, M. D., Wijesuriya, S. J., Ou, X. and Hauer-Jensen, M. Up-regulation and Activation of Proteinase-Activated Receptor 2 in Early…”
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Proteinase-activated receptors (PARs) and the kidney
Published in Drug development research (01-09-2003)“…It has been discovered that the kidney is an organ that is particularly rich in proteinase‐activated receptor‐2 (PAR2) and that also expresses PARs 1 and 4…”
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