Search Results - "Wight, Andrew E"

Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain by Shen, Xianli, Qiu, Yiguo, Wight, Andrew E, Kim, Hye-Jung, Cantor, Harvey

“…Expression of (encoding the CD11c surface protein) and (encoding osteopontin; OPN) has been associated with activated microglia that can develop in healthy…”
Get full text

Definition of the contribution of an Osteopontin-producing CD11c + microglial subset to Alzheimer's disease by Qiu, Yiguo, Shen, Xianli, Ravid, Orly, Atrakchi, Dana, Rand, Daniel, Wight, Andrew E, Kim, Hye-Jung, Liraz-Zaltsman, Sigal, Cooper, Itzik, Schnaider Beeri, Michal, Cantor, Harvey

“…Alzheimer's disease (AD) is the most common form of incurable dementia and represents a critical public health issue as the world's population ages. Although…”
Get full text

Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy by Wight, Andrew E, Sido, Jessica M, Degryse, Sandrine, Ao, Lin, Nakagawa, Hidetoshi, Qiu Vivian, Yiguo, Shen, Xianli, Oseghali, Oba, Kim, Hye-Jung, Cantor, Harvey

“…Regulatory T cells (Treg) can impede antitumor immunity and currently represent a major obstacle to effective cancer immunotherapy. Targeting…”
Get full text

A narrow T cell receptor repertoire instructs thymic differentiation of MHC class Ib-restricted CD8+ regulatory T cells by Kim, Hye-Jung, Nakagawa, Hidetoshi, Choi, John Y, Che, Xuchun, Divris, Andrew, Liu, Qingshi, Wight, Andrew E, Zhang, Hengcheng, Saad, Anis, Solhjou, Zhabiz, Deban, Christa, Azzi, Jamil R, Cantor, Harvey

“…Although most CD8+ T cells are equipped to kill infected or transformed cells, a subset may regulate immune responses and preserve self-tolerance. Here, we…”
Get full text

A narrow T cell receptor repertoire instructs thymic differentiation of MHC class Ib–restricted CD8+ regulatory T cells by Kim, Hye-Jung, Nakagawa, Hidetoshi, Choi, John Y, Che, Xuchun, Divris, Andrew, Liu, Qingshi, Wight, Andrew E, Zhang, Hengcheng, Saad, Anis, Solhjou, Zhabiz, Deban, Christa, Azzi, Jamil R, Cantor, Harvey

“…Although most CD8+T cells are equipped to kill infected ortransformed cells, a subset may regulate immune responses and preserve self-tolerance. Here, we…”
Get full text

A narrow T cell receptor repertoire instructs thymic differentiation of MHC class Ib-restricted [CD8.sup.+] regulatory T cells by Kim, Hye-Jung, Nakagawa, Hidetoshi, Choi, John Y, Che, Xuchun, Divris, Andrew, Liu, Qingshi, Wight, Andrew E, Zhang, Hengcheng, Saad, Anis, Solhjou, Zhabiz, Deban, Christa, Azzi, Jamil R, Cantor, Harvey

“…Although most [CD8.sup.+] T cells are equipped to kill infected or transformed cells, a subset may regulate immune responses and preserve self-tolerance. Here,…”
Get full text

A tumor-infiltrating IL23R-expressing CD4+ Treg population represents a safe and potent immunotherapeutic candidate in mice by Wight, Andrew E, Sido, Jessica Margaret, Degryse, Sandrine, Oseghali, Oba, Ao, Lin, Nakagawa, Hidatoshi, Kim, Hye-Jung, Cantor, Harvey

“…Abstract Interleukin 23 receptor (IL23R) is a signaling protein normally implicated in gut T cell development, but which has also been correlated with poor…”
Get full text