Search Results - "Wiggers, Helton J."

Non-peptidic cruzain inhibitors with trypanocidal activity discovered by virtual screening and in vitro assay by Wiggers, Helton J, Rocha, Josmar R, Fernandes, William B, Sesti-Costa, Renata, Carneiro, Zumira A, Cheleski, Juliana, da Silva, Albérico B F, Juliano, Luiz, Cezari, Maria H S, Silva, João S, McKerrow, James H, Montanari, Carlos A

“…A multi-step cascade strategy using integrated ligand- and target-based virtual screening methods was developed to select a small number of compounds from the…”
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From Burst to Sustained Release: The Effect of Antibiotic Structure Incorporated into Chitosan-Based Films by Sczesny, Nathália F., Wiggers, Helton J., Bueno, Cecilia Z., Chevallier, Pascale, Copes, Francesco, Mantovani, Diego

“…Background/Objectives: Medical devices are susceptible to bacterial colonization and biofilm formation, which can result in severe infections, leading to…”
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Structural and thermodynamic studies of two centrin isoforms from Blastocladiella emersonii upon calcium binding by Camargo, Ana I., Wiggers, Helton J., Damalio, Julio C.P., Araujo, Ana P.U., Ribichich, Karina F., de Camargo, Paulo C.

“…Centrins are calcium-binding proteins associated with microtubules organizing centers. Members of two divergent subfamilies of centrins were found in the…”
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Identification of Anti-Inflammatory and Anti-Hypertensive Drugs as Inhibitors of Bacterial Diguanylate Cyclases by Wiggers, Helton, Crusca, Edson, Silva, Éverton, Cheleski, Juliana, Torres, Naiara, Navarro, Marcos

“…Biofilms are widely present in many human chronic infections, often more resistant to treatment with antibiotics. Bacterial diguanylate cyclases (DGCs)…”
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Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay: e2370 by Wiggers, Helton J, Rocha, Josmar R, Fernandes, William B, Sesti-Costa, Renata, Carneiro, Zumira A, Cheleski, Juliana, Silva, B Fda, Juliano, Luiz, Cezari, Maria HS, Silva, João S, McKerrow, James H, Montanari, Carlos A

“…A multi-step cascade strategy using integrated ligand- and target-based virtual screening methods was developed to select a small number of compounds from the…”
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A new bianthron glycoside as inhibitor of Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase activity by Macedo, Edângelo M. S. de, Wiggers, Helton J., Silva, Maria G. V., Braz-Filho, Raimundo, Andricopulo, Adriano D., Montanari, Carlos A.

“…A phytochemical investigation of the ethanolic extract of stalks of Senna martiana Benth. (Leguminoseae), native specie of northeast Brazil, resulted in the…”
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