Search Results - "Wiget, Paul A"

Regioselective alkylation of a versatile indazole: Electrophile scope and mechanistic insights from density functional theory calculations by Lu, Pengcheng, Juarez, Luis, Wiget, Paul A, Zhang, Weihe, Raman, Krishnan, Kotian, Pravin L

“…Herein, we report a pair of regioselective - and alkylations of a versatile indazole, methyl 5-bromo-1 -indazole-3-carboxylate ( ) and the use of density…”
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Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics by Wiget, Paul A., Manzano, Lawrence A., Pruet, Jeff M., Gao, Grace, Saito, Ryota, Monzingo, Arthur F., Jasheway, Karl R., Robertus, Jon D., Anslyn, Eric V.

“…Several 7-aminoamido-pterins were synthesized to evaluate the electronic and biochemical subtleties observed in the ‘linker space’ when…”
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A novel stereoselective [8+2] double cycloaddition route to hydronaphthalene ring systems by Ying, Weijiang, Zhang, Lei, Wiget, Paul A., Herndon, James W.

“…[Display omitted] •One-step formation of densely functionalized naphthalenes in one reaction flask.•Novel rearrangement of [8+2] cycloaddition products via…”
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Electronic Donation or Steric Contraction: A Spectroscopic and Structural Analysis of Medium-Sized Constrained Rings for Potential Long-Range Hyperconjugation by Lee, Robert, Bashrum, Bryan, Cagle, Ethan C, Walters, Jillian, Massey, Jake, Zanghi, Monica, Birchfield, Carolyn, French, David, Joy, Jessica, dos Passos Gomes, Gabriel, Wiget, Paul A

“…Herein, we report the 1 J CH analyses, natural bond orbital analyses, and X-ray crystal structures of a number of C, O, and N constrained tricyclic cycles…”
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Discovery of a Long-Range Perlin Effect in a Conformationally Constrained Oxocane by Berry, Ellen, Gomes, Gabriel dos Passos, MacLean, Alex, Martin, Justin R, Wiget, Paul A

“…Herein, we present the crystal structure, NMR J analysis, and conformational and natural bond order analyses of tricyclic oxocane (1), resulting in the…”
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Peptide-Conjugated Pterins as Inhibitors of Ricin Toxin A by Saito, Ryota, Pruet, Jeff M, Manzano, Lawrence A, Jasheway, Karl, Monzingo, Arthur F, Wiget, Paul A, Kamat, Ishan, Anslyn, Eric V, Robertus, Jon D

“…Several 7-peptide-substituted pterins were synthesized and tested as competitive active-site inhibitors of ricin toxin A (RTA). Focus began on dipeptide…”
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Optimized 5-Membered Heterocycle-Linked Pterins for the Inhibition of Ricin Toxin A by Pruet, Jeff M, Saito, Ryota, Manzano, Lawrence A, Jasheway, Karl R, Wiget, Paul A, Kamat, Ishan, Anslyn, Eric V, Robertus, Jon D

“…The optimization of a series of pterin amides for use as Ricin Toxin A (RTA) inhibitors is reported. On the basis of crystallographic data of a previous…”
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Bicyclic cycloadduct fragmentations as a means of stereocontrol by Brandau, Nicole M., Wiget, Paul A.

“…[Display omitted] •Discussion of fragmented cycloadducts in total synthesis.•Discussion of stereoinduction from cycloadducts in total synthesis.•Retrosynthetic…”
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Synthesis of dienylfurans and their reactions with electron-deficient alkynes by Wiget, Paul A

“…Dienylfurans present vast potential as [8+2] cycloaddition coupling partners with electron-deficient alkynes creating incredible molecular complexity in a…”
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Synthesis of dienylfurans and their reactions with electron-deficient alkynes by Wiget, Paul A

“…Dienylfurans present vast potential as [8+2] cycloaddition coupling partners with electron-deficient alkynes creating incredible molecular complexity in a…”
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