Search Results - "Wigent, Rodney J"

Drug-polymer interaction and its significance on the physical stability of nifedipine amorphous dispersion in microparticles of an ammonio methacrylate copolymer and ethylcellulose binary blend by Huang, Jingjun, Wigent, Rodney J, Schwartz, Joseph B

“…Using spectroscopic and thermal analysis, this study investigated drug-polymer interaction and its significance on the physical stability of drug amorphous…”
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Interplay of formulation and process methodology on the extent of nifedipine molecular dispersion in polymers by Huang, Jingjun, Li, Ying, Wigent, Rodney J., Malick, Waseem A., Sandhu, Harpreet K., Singhal, Dharmendra, Shah, Navnit H.

“…The aim of this study is to evaluate effects of formulation and process technology on drug molecular dispersibility in solid dispersions (SDs). Nifedipine…”
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Nifedipine Molecular Dispersion in Microparticles of Ammonio Methacrylate Copolymer and Ethylcellulose Binary Blends for Controlled Drug Delivery: Effect of Matrix Composition by Huang, Jingjun, Wigent, Rodney J., Schwartz, Joseph B.

“…ABSTRACT The objective of this study is to explore matrix-type microparticles, comprising a solid dispersion of drug with an ammonio methacrylate copolymer and…”
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Nifedipine solid dispersion in microparticles of ammonio methacrylate copolymer and ethylcellulose binary blend for controlled drug delivery Effect of drug loading on release kinetics by JINGJUN HUANG, WIGENT, Rodney J, BENTZLEY, Catherine M, SCHWARTZ, Joseph B

“…In order to elucidate the controlled-release mechanism of a poorly water-soluble drug from microparticles of ammonio methacrylate copolymer and ethylcellulose…”
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Use of к-carrageenan, chitosan and Carbopol 974P in extruded and spheronized pellets that are devoid of MCC by Valle, Brenda L., Omwancha, Wycliffe S., Neau, Steven H., Wigent, Rodney J.

“…The search for excipients to replace microcrystalline cellulose (MCC) in the production of pellets by extrusion-spheronization in cases of drug incompatibility…”
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Thermogravimetric Analysis for the Determination of Water Release Rate from Microcrystalline Cellulose Dry Powder and Wet Bead Systems by Mayville, Francis C., Wigent, Rodney J., Schwartz, Joseph B.

“…The purpose of this work was to determine the total amount of water contained in dry powder and wet bead samples of microcrystalline cellulose, MCC, (Avicel®…”
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Characterization and in vitro release of methotrexate from gelatin/methotrexate conjugates formed using different preparation variables by Kosasih, A, Bowman, Bill J, Wigent, Rodney J, Ofner, Clyde M

“…The purpose of this study was to evaluate effects of preparation variables on the composition of gelatin-methotrexate conjugates, and to evaluate their in…”
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Thermodynamic analysis of compact formation; compaction, unloading, and ejection: II. Mechanical energy (work) and thermal energy (heat) determinations of compact unloading and ejection by DeCrosta, Mark T, Schwartz, Joseph B, Wigent, Rodney J, Marshall, Keith

“…A compaction calorimeter, previously described (DeCrosta, M.T., Schwartz, J.B., Wigent, J.B., Marshall, K., 2000. Thermodynamic analysis of compact formation;…”
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Drug Release from Film-Coated Chlorpheniramine Maleate Nonpareil Beads: Water Influx and Development of a New Drug Release Model by Tang, Lijuan, Wigent, Rodney J., Schwartz, Joseph B.

“…The purpose of this work was to investigate drug release from film-coated chlorpheniramine maleate (CPM) nonpareils (sugar spheres) and the effect of water…”
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The Effect of Humidity on Samples of Microcrystalline Cellulose Taken From the Extrusion Marumerization Process by Mayville, Francis C., Atassi, Faraj, Wigent, Rodney J., Schwartz, Joseph B.

“…The purpose of this work was to examine the sorption and desorption of water by various samples of microcrystalline cellulose, MCC (Avicel® PH-101), taken from…”
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Nifedipine solid dispersion in microparticles of ammonio methacrylate copolymer and ethylcellulose binary blend for controlled drug delivery by Huang, Jingjun, Wigent, Rodney J., Bentzley, Catherine M., Schwartz, Joseph B.

“…In order to elucidate the controlled-release mechanism of a poorly water-soluble drug from microparticles of ammonio methacrylate copolymer and ethylcellulose…”
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Determination of osmotic and activity coefficients in mixed electrolyte systems. Systems containing clathrate-forming salts by Wigent, Rodney J, Leifer, Leslie

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Determination of the contribution of pair, triplet, and higher-order multiplet interactions to the excess free energy of mixing in mixed electrolyte solutions by Leifer, Leslie, Wigent, Rodney J

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Thermodynamic analysis of compact formation; compaction, unloading, and ejectionII. Mechanical energy (work) and thermal energy (heat) determinations of compact unloading and ejection by DeCrosta, Mark T, Schwartz, Joseph B, Wigent, Rodney J, Marshall, Keith

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Thermodynamic analysis of compact formation; compaction, unloading, and ejection by DeCrosta, Mark T., Schwartz, Joseph B., Wigent, Rodney J., Marshall, Keith

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Thermodynamic analysis of compact formation; compaction, unloading, and ejection: I. Design and development of a compaction calorimeter and mechanical and thermal energy determinations of powder compaction by DeCrosta, Mark T., Schwartz, Joseph B., Wigent, Rodney J., Marshall, Keith

“…The aim of this investigation was to determine and evaluate the thermodynamic properties, i.e. heat, work, and internal energy change, of the compaction…”
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Drug Release from Film-Coated Chlorpheniramine Maleate Nonpareil Beads: Effect of Water-Soluble Polymer, Coating Level, and Soluble Core Material by Tang, Lijuan, Schwartz, Joseph B., Porter, Stuart C., Schnaare, Roger L., Wigent, Rodney J.

“…The purpose of this research was to use a new drug release model to study the effects of formulation parameters on drug release from a film-coated…”
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Differences in the mechanical strength of dried microcrystalline cellulose pellets are not due to significant changes in the degree of hydrogen bonding by Millili, G P, Wigent, R J, Schwartz, J B

“…The mechanical strengths of oven-dried pellets of microcrystalline cellulose, MCC, prepared by extruder/marumerizer technology are weaker when ethanol/water…”
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Charge-transfer complexes of iodine and nonionic surfactants: interpretation and use in the Winkler method by Nowaczyk, Jr, F J, Schnaare, R L, Wigent, R J, Ofner, 3rd, C M

“…Formation constants (Kc) and molar absorption coefficients (epsilon c) of complexes of iodine and various nonionic surfactants were determined, providing a…”
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