Search Results - "Wiethe, Carsten"

Enhancement of Capsid Gene Expression: Preparing the Human Papillomavirus Type 16 Major Structural Gene L1 for DNA Vaccination Purposes by Leder, C, Kleinschmidt, J A, Wiethe, C, Müller, M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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OMIP‐93: A 41‐color high parameter panel to characterize various co‐inhibitory molecules and their ligands in the lymphoid and myeloid compartment in mice by Brandi, Johannes, Wiethe, Carsten, Riehn, Mathias, Jacobs, Thomas

“…This 41‐color panel has been designed to characterize both the lymphoid and the myeloid compartments in mice. The number of immune cells isolated from organs…”
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A Rapid, Calcium-independent Mojosort &[trade] Dead Cell Removal Kit for Improved Live Cell Enrichment and Downstream Application by Zhang, Hong, Ruiz, Jen, Yamamoto, Kenta, Taylor, Kevin, Wiethe, Carsten, Yang, Xifeng

“…Abstract High sample cell viability is crucial for obtaining high-quality data for various downstream applications. Commonly used methods include density…”
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The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis by Weisel, Florian, Winkler, Thomas H, Neubert, Kirsten, Kalden, Joachim R, Meister, Silke, Maseda, Damian, Manz, Rudolf A, Wiethe, Carsten, Amann, Kerstin, Voll, Reinhard E, Moser, Katrin

“…Bortezomib, a drug useful for the treatment of multiple myeloma, reduces kidney damage in animal models of lupus. Autoantibody-mediated diseases like…”
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Optimized full-spectrum flow cytometry panel for deep immunophenotyping of murine lungs by Baumann, Zora, Wiethe, Carsten, Vecchi, Cinja M., Richina, Veronica, Lopes, Telma, Bentires-Alj, Mohamed

“…The lung immune system consists of both resident and circulating immune cells that communicate intricately. The immune system is activated by exposure to…”
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Dendritic Cell Differentiation State and Their Interaction with NKT Cells Determine Th1/Th2 Differentiation in the Murine Model of Leishmania major Infection by Wiethe, Carsten, Debus, Andrea, Mohrs, Markus, Steinkasserer, Alexander, Lutz, Manfred, Gessner, Andre

“…Recent reports demonstrated that dendritic cells (DC) sense inflammatory and microbial signals differently, redefining their classical subdivision into an…”
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CD83 Expression in CD4+ T Cells Modulates Inflammation and Autoimmunity by Reinwald, Simone, Wiethe, Carsten, Westendorf, Astrid M, Breloer, Minka, Probst-Kepper, Michael, Fleischer, Bernhard, Steinkasserer, Alexander, Buer, Jan, Hansen, Wiebke

“…The transmembrane protein CD83 has been initially described as a maturation marker for dendritic cells. Moreover, there is increasing evidence that CD83 also…”
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Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro by Rößner, Susanne, Voigtländer, Constanze, Wiethe, Carsten, Hänig, Jens, Seifarth, Christian, Lutz, Manfred B.

“…Tolerogenic activity of myeloid dendritic cells (DC) has so far been attributed mostly to immature or semi‐mature differentiation stages but never to their…”
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MojoSort: a versatile nanoparticle for magnetic isolation of cells with high purity, yield, and preserved functionality (TECH2P.926) by Zhang, Hong, Tam, Miguel, Gohel, Dhanesh, Zhao, Xinfang, Koury, Jeffery, Wiethe, Carsten, Yang, Xifeng, Ransom, John, Monell, Craig, Jiang, Nan, Lay, Gene

“…Abstract The isolation of specific cells from a complex population is a technical challenge that researchers face very often. Several strategies have emerged…”
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Blocking ADP-ribosylation of cell surface proteins during cell preparation with a Nanobody against ART2 enhances chemotaxis of T cells during in vitro migration assays. (P3388) by Moyron-Quiroz, Juan, Rissiek, Björn, Soto, Hortensia, Pahuja, Anil, Wiethe, Carsten, Zlotnik, Albert, Yang, Xifeng, Koch-Nolte, Friedrich, Ransom, John

“…Abstract ADP-ribosylation is the enzymatic transfer of the ADP-ribose moiety from NAD+ to a protein, a posttranslational modification that regulates the…”
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Revealing viral and cellular dynamics of HIV-1 at the single-cell level during early treatment periods by Otte, Fabian, Zhang, Yuepeng, Spagnuolo, Julian, Thielen, Alexander, Däumer, Martin, Wiethe, Carsten, Stoeckle, Marcel, Kusejko, Katharina, Klein, Florian, Metzner, Karin J., Klimkait, Thomas, Abela, I., Aebi-Popp, K., Anagnostopoulos, A., Battegay, M., Bernasconi, E., Braun, D.L., Bucher, H.C., Calmy, A., Cavassini, M., Ciuffi, A., Dollenmaier, G., Egger, M., Elzi, L., Fehr, J., Fellay, J., Furrer, H., Fux, C.A., Günthard, H.F., Hachfeld, A., Haerry, D., Hasse, B., Hirsch, H.H., Hoffmann, M., Hösli, I., Huber, M., Jackson-Perry, D., Kahlert, C.R., Kaiser, L., Keiser, O., Klimkait, T., Kouyos, R.D., Kovari, H., Kusejko, K., Labhardt, N., Leuzinger, K., Martinez de Tejada, B., Marzolini, C., Metzner, K.J., Müller, N., Nemeth, J., Nicca, D., Notter, J., Paioni, P., Pantaleo, G., Perreau, M., Rauch, A., Salazar-Vizcaya, L., Schmid, P., Speck, R., Stöckle, M., Tarr, P., Trkola, A., Wandeler, G., Weisser, M., Yerly, S.

“…While combination therapy completely suppresses HIV-1 replication in blood, functional virus persists in CD4+ T cell subsets in non-peripheral compartments…”
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Simultaneous Induction of CD4 T Cell Tolerance and CD8 T Cell Immunity by Semimature Dendritic Cells by Kleindienst, Petra, Wiethe, Carsten, Lutz, Manfred B, Brocker, Thomas

“…Previous studies suggested that depending on their maturation state, dendritic cells (DC) could either induce T cell tolerance (immature and semimature DC) or…”
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Provision of 4-1BB Ligand Enhances Effector and Memory CTL Responses Generated by Immunization with Dendritic Cells Expressing a Human Tumor-Associated Antigen by Wiethe, Carsten, Dittmar, Kurt, Doan, Tracy, Lindenmaier, Werner, Tindle, Robert

“…Up-regulation of receptor-ligand pairs during interaction of an MHC-presented epitope on dendritic cells (DCs) with cognate TCR may amplify, sustain, and drive…”
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Dendritic cells matured with TNF can be further activated in vitro and after subcutaneous injection in vivo which converts their tolerogenicity into immunogenicity by Voigtländer, Constanze, Rössner, Susanne, Cierpka, Eva, Theiner, Gabi, Wiethe, Carsten, Menges, Mauritius, Schuler, Gerold, Lutz, Manfred B

“…Dendritic cell (DC) maturation can occur by different types of stimuli. Previously, we described that murine DC matured with tumor necrosis factor (TNF)…”
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Interdependency of MHC Class II/Self-Peptide and CD1d/Self-Glycolipid Presentation by TNF-Matured Dendritic Cells for Protection from Autoimmunity by Wiethe, Carsten, Schiemann, Matthias, Busch, Dirk, Haeberle, Lothar, Kopf, Manfred, Schuler, Gerold, Lutz, Manfred B

“…Dendritic cells (DC) are key regulators of T cell immunity and tolerance. NKT cells are well-known enhancers of Th differentiation and regulatory T cell…”
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Enhanced effector and memory CTL responses generated by incorporation of receptor activator of NF-kappa B (RANK)/RANK ligand costimulatory molecules into dendritic cell immunogens expressing a human tumor-specific antigen by Wiethe, Carsten, Dittmar, Kurt, Doan, Tracy, Lindenmaier, Werner, Tindle, Robert

“…The outcome of dendritic cell (DC) presentation of Ag to T cells via the TCR/MHC synapse is determined by second signaling through CD80/86 and, importantly, by…”
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Co-immunisation with DNA encoding RANK/RANKL or 4-1BBL costimulatory molecules does not enhance effector or memory CTL responses afforded by immunisation with a tumour antigen-encoding DNA vaccine by Herd, Karen A, Wiethe, Carsten, Tindle, Robert W

“…Abstract T cell mediated immune responses are induced following interaction of MHC-presented epitope on professional antigen presenting cells such as dendritic…”
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CD83 Expression in CD4 super(+) T Cells Modulates Inflammation and Autoimmunity by Reinwald, Simone, Wiethe, Carsten, Westendorf, Astrid M, Breloer, Minka, Probst-Kepper, Michael, Fleischer, Bernhard, Steinkasserer, Alexander, Buer, Jan, Hansen, Wiebke

“…The transmembrane protein CD83 has been initially described as a maturation marker for dendritic cells. Moreover, there is increasing evidence that CD83 also…”
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Minor Role of Bystander Tolerance to Fetal Calf Serum in a Peptide-specific Dendritic Cell Vaccine Model Against Autoimmunity : Comparison With Serum-free Cultures by RÖSSNER, Susanne, ZINSER, Elisabeth, MENGES, Mauritius, WIETHE, Carsten, LITTMANN, Leonie, HÄNIG, Jens, STEINKASSERER, Alexander, LUTZ, Manfred B

“…Dendritic cells (DCs) are currently considered as promising tools for vaccination against tumors and also autoimmune responses. A major point of concern has…”
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Enhanced Effector and Memory CTL Responses Generated by Incorporation of Receptor Activator of NF-{kappa}B (RANK)/RANK Ligand Costimulatory Molecules into Dendritic Cell Immunogens Expressing a Human Tumor-Specific Antigen by Wiethe, Carsten, Dittmar, Kurt, Doan, Tracy, Lindenmaier, Werner, Tindle, Robert

“…The outcome of dendritic cell (DC) presentation of Ag to T cells via the TCR/MHC synapse is determined by second signaling through CD80/86 and, importantly, by…”
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