Search Results - "Wiesmeijer, Karien C"
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A rapid assay for on-site monitoring of infliximab trough levels: a feasibility study
Published in Analytical and bioanalytical chemistry (01-09-2013)“…Monitoring levels of biologicals against tumor necrosis factor (TNF) has been suggested to improve therapeutic outcomes in inflammatory bowel diseases (IBDs)…”
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BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice
Published in International journal of molecular sciences (18-02-2021)“…Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor . Endoglin haploinsufficiency…”
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Inhibiting DPP4 in a mouse model of HHT1 results in a shift towards regenerative macrophages and reduces fibrosis after myocardial infarction
Published in PloS one (18-12-2017)“…Hereditary Hemorrhagic Telangiectasia type-1 (HHT1) is a genetic vascular disorder caused by haploinsufficiency of the TGFβ co-receptor endoglin. Dysfunctional…”
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The BMP Receptor 2 in Pulmonary Arterial Hypertension: When and Where the Animal Model Matches the Patient
Published in Cells (Basel, Switzerland) (08-06-2020)“…Mutations in bone morphogenetic protein receptor type II (BMPR2) are leading to the development of hereditary pulmonary arterial hypertension (PAH). In…”
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Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling
Published in The European respiratory journal (01-09-2019)“…Pulmonary arterial hypertension (PAH) is a progressive fatal disease characterised by abnormal remodelling of pulmonary vessels, leading to increased vascular…”
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Cardiac Progenitor Cell–Derived Extracellular Vesicles Reduce Infarct Size and Associate with Increased Cardiovascular Cell Proliferation
Published in Journal of cardiovascular translational research (01-02-2019)“…Cell transplantation studies have shown that injection of progenitor cells can improve cardiac function after myocardial infarction (MI). Transplantation of…”
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Lateral flow assay for simultaneous detection of cellular- and humoral immune responses
Published in Clinical biochemistry (01-10-2011)“…The development of a cytokine detection assay suitable for detection of multiple biomarkers for improved diagnosis of mycobacterial diseases. A lateral flow…”
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Prenatal diagnosis of trisomy 13 on fetal cells obtained from maternal blood after minor enrichment
Published in Prenatal diagnosis (01-10-1998)“…In a pilot study to establish fetal nucleated red blood cell (NRBC) detection in maternal blood, trisomy 13 was diagnosed by FISH analysis at 11 weeks'…”
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Fetal cell detection in maternal blood: A study in 236 samples using erythroblast morphology, DAB and Hbf staining, and FISH analysis
Published in Cytometry (New York, N.Y.) (01-07-1998)“…A protocol to detect fetal nucleated red blood cells (NRBCs) was tested in 217 pregnant women and in 19 nonpregnant controls. All the pregnant women were…”
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Development of a preparation and staining method for fetal erythroblasts in maternal blood: Simultaneous immunocytochemical staining and FISH analysis
Published in Cytometry (New York, N.Y.) (01-07-1998)“…In order to detect fetal nucleated red blood cells (NRBCs) in maternal blood, a protocol was developed which aimed at producing a reliable staining method for…”
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