Search Results - "Wieske, F."
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Early neuromodulation prevents the development of brain and behavioral abnormalities in a rodent model of schizophrenia
Published in Molecular psychiatry (01-04-2018)“…The notion that schizophrenia is a neurodevelopmental disorder in which neuropathologies evolve gradually over the developmental course indicates a potential…”
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Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue
Published in Molecular genetics and metabolism reports (01-06-2015)“…Methylenetetrahydrofolate reductase (MTHFR) is an enzyme key regulator in folate metabolism. Deficiencies in MTHFR result in increased levels of homocysteine,…”
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Loss of EphA4 impairs short‐term spatial recognition memory performance and locomotor habituation
Published in Genes, brain and behavior (01-11-2012)“…EphA4 receptor (EphA4) tyrosine kinase is an important regulator of central nervous system development and synaptic plasticity in the mature brain, but its…”
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EP 68. Identification of electrophysiological biomarkers in a novel animal model of Tourette Syndrome
Published in Clinical neurophysiology (01-09-2016)“…Introduction Treating Tourette syndrome (TS) remains challenging as therapies fail to take temporal presentation of symptoms into account. Therefore, to…”
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Paradoxical augmented relapse in alcohol-dependent rats during deep-brain stimulation in the nucleus accumbens
Published in Translational psychiatry (21-06-2016)“…Case reports indicate that deep-brain stimulation in the nucleus accumbens may be beneficial to alcohol-dependent patients. The lack of clinical trials and our…”
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Medial Forebrain Bundle Deep Brain Stimulation has Symptom-specific Anti-depressant Effects in Rats and as Opposed to Ventromedial Prefrontal Cortex Stimulation Interacts With the Reward System
Published in Brain stimulation (01-07-2015)“…Abstract Background In recent years, deep brain stimulation (DBS) has emerged as a promising treatment option for patients suffering from treatment-resistant…”
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