Search Results - "Wiesen, Martin H. J."

Glycyrrhizic Acid Prevents Paclitaxel-Induced Neuropathy via Inhibition of OATP-Mediated Neuronal Uptake by Klein, Ines, Isensee, Jörg, Wiesen, Martin H J, Imhof, Thomas, Wassermann, Meike K, Müller, Carsten, Hucho, Tim, Koch, Manuel, Lehmann, Helmar C

“…Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The mechanisms by which paclitaxel is transported into neurons, which are…”
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Pharmacodynamic Monitoring of Mycophenolic Acid Therapy: Improved Liquid Chromatography–Tandem Mass Spectrometry Method for Measuring Inosin-5′-Monophosphate Dehydrogenase Activity by Weißbarth, Gero, Wiesen, Martin H. J., Fietz, Cornelia, Streichert, Thomas, Ehren, Rasmus, Weber, Lutz T., Müller, Carsten

“…Mycophenolic acid (MPA), a powerful inhibitor of lymphocyte proliferation, is widely used in transplantation medicine and as a glucocorticoid-sparing agent in…”
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The role of sex and weight on rituximab clearance and serum elimination half-life in elderly patients with DLBCL by Müller, Carsten, Murawski, Niels, Wiesen, Martin H.J., Held, Gerhard, Poeschel, Viola, Zeynalova, Samira, Wenger, Michael, Nickenig, Christina, Peter, Norma, Lengfelder, Eva, Metzner, Bernd, Rixecker, Tanja, Zwick, Carsten, Pfreundschuh, Michael, Reiser, Marcel

“…Pharmacokinetics of 8 doses of rituximab (375 mg/m2) given in combination with 2-week cyclophosphamide, hydroxydaunorubicin, vincristine, and…”
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Monitoring of sedation depth in intensive care unit by therapeutic drug monitoring? A prospective observation study of medical intensive care patients by Nies, Richard J, Müller, Carsten, Pfister, Roman, Binder, Philipp S, Nosseir, Nicole, Nettersheim, Felix S, Kuhr, Kathrin, Wiesen, Martin H J, Kochanek, Matthias, Michels, Guido

“…Analgosedation is a cornerstone therapy for mechanically ventilated patients in intensive care units (ICU). To avoid inadequate sedation and its complications,…”
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Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers by Bilal, Muhammad, Ullah, Sami, Jaehde, Ulrich, Trueck, Christina, Zaremba, Dario, Wachall, Bertil, Wargenau, Manfred, Scheidel, Bernhard, Wiesen, Martin H. J., Gazzaz, Malaz, Chen, Chunli, Büsker, Sören, Fuhr, Uwe, Taubert, Max, Dokos, Charalambos

“…Purpose Currently, body weight-based dosing of rifampicin is recommended. But lately, fat-free mass (FFM) was reported to be superior to body weight (BW). The…”
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Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease by Tahmaz, Volkan, Wiesen, Martin H. J., Gehlsen, Uta, Sauerbier, Laura, Stern, Michael E., Holtick, Udo, Gathof, Birgit, Scheid, Christof, Müller, Carsten, Steven, Philipp

“…Purpose Chronic graft versus host disease is a major consequence after allogeneic stem cell transplantation (allo-SCT) and has great impact on patients’…”
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Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum by Müller, Carsten, Fietz, Cornelia, Koehler, Philipp, Sibley, Graham, Nforbugwe, Achu Che Awah, Streichert, Thomas, Wiesen, Martin H J

“…A fast and easy-to-use liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination and quantification of a novel antifungal drug,…”
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Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum by Müller, Carsten, Gehlen, David, Blaich, Cornelia, Prozeller, Domenik, Liss, Blasius, Streichert, Thomas, Wiesen, Martin H J

“…A fast and easy-to-use liquid chromatography-tandem mass spectrometry method for the determination and quantification of 6 triazoles [fluconazole (FLZ),…”
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A Semi-Mechanistic Population Pharmacokinetic Model of Noscapine in Healthy Subjects Considering Hepatic First-Pass Extraction and CYP2C9 Genotypes by Chen, Zhendong, Taubert, Max, Chen, Chunli, Boland, Jana, Dong, Qian, Bilal, Muhammad, Dokos, Charalambos, Wachall, Bertil, Wargenau, Manfred, Scheidel, Bernhard, Wiesen, Martin H. J., Schaeffeler, Elke, Tremmel, Roman, Schwab, Matthias, Fuhr, Uwe

“…Introduction Noscapine is a commonly used cough suppressant, with ongoing research on its anti-inflammatory and anti-tumor properties. The drug has a…”
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Remifentanil Degradation in Umbilical Cord Blood of Preterm Infants by WELZING, Lars, EBENFELD, Sabine, DLUGAY, Verena, WIESEN, Martin H. J, ROTH, Bernhard, MUELLER, Carsten

“…No pharmacokinetic data about remifentanil in preterm infants exist, although remifentanil is increasingly used in this especially vulnerable subgroup of…”
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Glia from the central and peripheral nervous system are differentially affected by paclitaxel chemotherapy via modulating their neuroinflammatory and neuroregenerative properties by Klein, Ines, Boenert, Janne, Lange, Felix, Christensen, Britt, Wassermann, Meike K., Wiesen, Martin H. J., Olschewski, Daniel Navin, Rabenstein, Monika, Müller, Carsten, Lehmann, Helmar C., Fink, Gereon Rudolf, Schroeter, Michael, Rueger, Maria Adele, Vay, Sabine Ulrike

“…Graphical Abstract Main Points: Paclitaxel differentially modulates inflammatory and regenerative properties of glial cells; Paclitaxel affects glia-glia and…”
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Quantification of direct‐acting oral anticoagulants: Application of a clinically validated liquid chromatography‐tandem mass spectrometry method to forensic cases by Wiesen, Martin H.J., Fietz, Cornelia, Jübner, Martin, Iwersen‐Bergmann, Stefanie, Andresen‐Streichert, Hilke, Müller, Carsten, Streichert, Thomas

“…In certain forensic cases, a quantification of direct‐acting oral anticoagulants (DOACs) can be necessary. We evaluate the applicability of a previously…”
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Liquid chromatography–tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device by Wiesen, Martin H.J., Farowski, Fedja, Feldkötter, Markus, Hoppe, Bernd, Müller, Carsten

“…► We present a method to simultaneously quantify MPA and MPAG in saliva and plasma. ► A collection device allowed standardized saliva collection and…”
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Layer-specific differences of gene expression in extraocular muscles identified by laser-capture microscopy by Budak, Murat T, Bogdanovich, Sasha, Wiesen, Martin H. J, Lozynska, Olga, Khurana, Tejvir S, Rubinstein, Neal A

“…1 Department of Cell and Developmental Biology and Pennsylvania Muscle Institute, University of Pennsylvania School of Medicine, Philadelphia 2 Department of…”
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Suboptimal dosing of rituximab in male and female patients with DLBCL by Pfreundschuh, Michael, Müller, Carsten, Zeynalova, Samira, Kuhnt, Evelyn, Wiesen, Martin H.J., Held, Gerhard, Rixecker, Tanja, Poeschel, Viola, Zwick, Carsten, Reiser, Marcel, Schmitz, Norbert, Murawski, Niels

“…To determine the effect of gender on outcome, the male hazard ratio for progression-free survival (HRPFS-male) was determined in patients with diffuse large…”
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Quantification of midostaurin in plasma and serum by stable isotope dilution liquid chromatography‐tandem mass spectrometry: Application to a cohort of patients with acute myeloid leukemia by Wiesen, Martin H. J., Stemler, Jannik, Fietz, Cornelia, Joisten, Carolin, Cornely, Oliver A., Verougstraete, Nick, Streichert, Thomas, Müller, Carsten

“…Objectives Midostaurin is an oral multitargeted tyrosine kinase inhibitor for the treatment of acute myeloid leukemia (AML). Therapeutic drug monitoring of…”
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Monitoring of Apixaban in a Super Obese Patient by Fietz, Cornelia, Michels, Guido, Müller, Carsten, Wiesen, Martin H.J.

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Identification and Characterization of Layer-Specific Differences in Extraocular Muscle M-Bands by Wiesen, Martin H. J, Bogdanovich, Sasha, Agarkova, Irina, Perriard, Jean-Claude, Khurana, Tejvir S

“…To examine and characterize the expression of M-bands (or M-lines) in the orbital layer (OL) and global layer (GL) of adult rat extraocular muscles (EOMs)…”
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The undetected murder? Evaluation and validation of a practicable and rapid inductively coupled plasma-mass spectrometry method for the detection of arsenic, lead, and thallium intoxications in postmortem blood by Wiesen, Martin H J, Schneider, Dennis, Hein, Wolfgang, Streichert, Thomas, Jübner, Martin, Andresen-Streichert, Hilke

“…Homicide, suicide, or accident - elemental intoxication may be a cause in each of these types of deaths. Inductively coupled plasma mass spectrometry (ICP-MS)…”
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Reliable and easy-to-use LC–MS/MS-method for simultaneous determination of the antihypertensives metoprolol, amlodipine, canrenone and hydrochlorothiazide in patients with therapy-refractory arterial hypertension by Johannsen, Jan-Ole, Reuter, Hannes, Hoffmann, Fabian, Blaich, Cornelia, Wiesen, Martin H.J., Streichert, Thomas, Müller, Carsten

“…•Reliable and easy-to-use LC–MS/MS-method for simultaneous determination of four antihypertensives (amlodipine, canrenone, hydrochlorothiazide, metoprolol) as…”
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