Search Results - "Wierenga, Jenny"
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Dissection and Modulation of the Four Distinct Activities of Nisin by Mutagenesis of Rings A and B and by C-Terminal Truncation
Published in Applied and Environmental Microbiology (01-09-2007)“…Nisin A is a pentacyclic antibiotic peptide produced by various Lactococcus lactis strains. Nisin displays four different activities: (i) it autoinduces its…”
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2
Production of Dehydroamino Acid-Containing Peptides by Lactococcus lactis
Published in Applied and Environmental Microbiology (01-03-2007)“…Nisin is a pentacyclic peptide antibiotic produced by some Lactococcus lactis strains. Nisin contains dehydroresidues and thioether rings that are…”
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3
Sec-Mediated Transport of Posttranslationally Dehydrated Peptides in Lactococcus lactis
Published in Applied and Environmental Microbiology (01-12-2006)“…Nisin is a lanthionine-containing antimicrobial peptide produced by Lactococcus lactis. Its (methyl)lanthionines are introduced by two posttranslational…”
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Mechanistic Dissection of the Enzyme Complexes Involved in Biosynthesis of Lacticin 3147 and Nisin
Published in Applied and Environmental Microbiology (01-11-2008)“…The thioether rings in the lantibiotics lacticin 3147 and nisin are posttranslationally introduced by dehydration of serines and threonines, followed by…”
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5
A Biological Porin Engineered into a Molecular, Nanofluidic Diode
Published in Nano letters (01-09-2007)“…We changed the nonrectifying biological porin OmpF into a nanofluidic diode. To that end, we engineered a pore that possesses two spatially separated…”
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Chemical Modification of the Bacterial Porin OmpF: Gain of Selectivity by Volume Reduction
Published in Biophysical journal (15-02-2006)“…OmpF is an essentially nonselective porin isolated from the outer membrane of Escherichia coli. Here we report on the manipulation of the ion selectivity of…”
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Permeation properties of an engineered bacterial OmpF porin containing the EEEE-locus of Ca2+ channels
Published in Biophysical journal (01-11-2004)“…The selectivity filter of the bacterial porin OmpF carries a small net charge close to -1 e and is therefore only slightly cation-selective. Calcium channels,…”
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8
Ca^sup 2+^ Selectivity of a Chemically Modified OmpF with Reduced Pore Volume
Published in Biophysical journal (15-12-2006)“…We studied an E. coli OmpF mutant (LECE) containing both an EEEE-like locus, typical of Ca^sup 2+^ channels, and an accessible and reactive cysteine. After…”
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Ca2+ selectivity of a chemically modified OmpF with reduced pore volume
Published in Biophysical journal (15-12-2006)“…We studied an E. coli OmpF mutant (LECE) containing both an EEEE-like locus, typical of Ca(2+) channels, and an accessible and reactive cysteine. After…”
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10
Permeation Properties of an Engineered Bacterial OmpF Porin Containing the EEEE-Locus of Ca^sup 2+^ Channels
Published in Biophysical journal (01-11-2004)“…The selectivity filter of the bacterial porin OmpF carries a small net charge close to -1 e and is therefore only slightly cation-selective. Calcium channels,…”
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Journal Article -
11
Ca 2+ Selectivity of a Chemically Modified OmpF with Reduced Pore Volume
Published in Biophysical journal (2006)“…We studied an E. coli OmpF mutant (LECE) containing both an EEEE-like locus, typical of Ca 2+ channels, and an accessible and reactive cysteine. After chemical…”
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12
Conductance and selectivity fluctuations in D127 mutants of the bacterial porin OmpF
Published in European biophysics journal (01-12-2006)“…A recent molecular dynamics study questioned the protonation state and physiological role of aspartate 127 (D127) of E. coli porin OmpF. To address that…”
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13
Permeation Properties of an Engineered Bacterial OmpF Porin Containing the EEEE-Locus of Ca 2+ Channels
Published in Biophysical journal (2004)“…The selectivity filter of the bacterial porin OmpF carries a small net charge close to −1 e and is therefore only slightly cation-selective. Calcium channels,…”
Get full text
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