Search Results - "Wierda, J M"

Biphasic EEG changes in relation to loss of consciousness during induction with thiopental, propofol, etomidate, midazolam or sevoflurane by Kuizenga, K, Wierda, J.M.K.H., Kalkman, C.J.

“…The time course of four EEG effect variables, amplitude in the 2–5 Hz and in the 11–15 Hz band, spectral edge frequency 95% (SEF95), and bispectral index…”
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Urinary, biliary and faecal excretion of rocuronium in humans by Proost, J.H., Eriksson, L.I., Mirakhur, R.K., Roest, G., Wierda, J.M.K.H.

“…The excretion of rocuronium and its potential metabolites was studied in 38 anaesthetized patients, ASA I–III and 21–69 yr old. Rocuronium bromide was…”
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Assessment of the clinical relevance of quantitative sensory testing with Von Frey monofilaments in patients with allodynia and neuropathic pain. A pilot study by Keizer, D., van Wijhe, M., Post, W. J., Uges, D. R. A., Wierda, J. M. K. H.

“…BACKGROUND:Allodynia is a common and disabling symptom in many patients with neuropathic pain. Whereas quantification of pain mostly depends on subjective pain…”
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Is time to peak effect of neuromuscular blocking agents dependent on dose? Testing the concept of buffered diffusion by Proost, J. H., Houwertjes, M. C., Wierda, J. M. K. H.

“…BACKGROUND AND OBJECTIVESFor neuromuscular blocking agents, an inverse relationship between potency and time to peak effect has been observed. To test the…”
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Model to describe the degree of twitch potentiation during neuromuscular monitoring by Eleveld, D.J., Kopman, A.F., Proost, J.H., Wierda, J.M.K.H.

“…Neuromuscular block is estimated by comparing the evoked peak twitch with a control value measured in the absence of neuromuscular block. In practice, this…”
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Pharmacodynamics and pharmacokinetics of rocuronium in intensive care patients by Sparr, H J, Wierda, J M, Proost, J H, Keller, C, Khuenl-Brady, K S

“…We have studied dose requirements, recovery times and pharmacokinetics of rocuronium in 32 intensive care patients. After an initial dose of 50 mg, rocuronium…”
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Time course of neuromuscular effects and pharmacokinetics of rocuronium bromide (Org 9426) during isoflurane anaesthesia in patients with and without renal failure by Cooper, R A, Maddineni, V R, Mirakhur, R K, Wierda, J M, Brady, M, Fitzpatrick, K T

“…We have studied the onset and duration of action and pharmacokinetics of rocuronium bromide (Org 9426) during anaesthesia with nitrous oxide, fentanyl and…”
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Transient nerve damage following intubation for trans-sphenoidal hypophysectomy by Evers, K A, Eindhoven, G B, Wierda, J M

“…To describe a case of transient lingual and hypoglossal nerve damage following intubation for a trans-sphenoidal hypophysectomy. A 56-yr-old acromegalic man…”
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Decreased number of acetylcholine receptors is the mechanism that alters the time course of muscle relaxants in myasthenia gravis: a study in a rat model by De Haes, A., Proost, J. H., De Baets, M. H., Stassen, M. H. W., Houwertjes, M. C., Wierda, J. M. K. H.

“…Summary Background: In myasthenic patients, the time course of action of non-depolarizing neuromuscular blocking agents is prolonged and the sensitivity is…”
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Current developments in anaesthesia and neuromuscular transmission by Wierda, J M, Mirakhur, R K

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Clinical observations on the neuromuscular blocking action of Org 9426, a new steroidal non-depolarizing agent by Wierda, J M, de Wit, A P, Kuizenga, K, Agoston, S

“…The neuromuscular blocking effects of Org 9426, the 2-morpholino, 16-allyl-pyrrolidino derivative of the 3-desacetoxy analogue of vecuronium have been…”
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A practical clinical approach to management of the difficult airway by Eindhoven, G B, Dercksen, B, Regtien, J G, Borg, P A, Wierda, J M

“…Difficult airway management represents a challenge in anaesthesia. In the last decades airway difficulty awareness has improved as a result of better…”
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Intubating conditions and onset of neuromuscular block of rocuronium (Org 9426); a comparison with suxamethonium by Huizinga, A C, Vandenbrom, R H, Wierda, J M, Hommes, F D, Hennis, P J

“…The intubating conditions and neuromuscular blocking profile following 600 micrograms.kg-1 rocuronium (Org 9426) have been investigated in patients under…”
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Pharmacodynamics and pharmacokinetics of an infusion of Org 9487, a new short-acting steroidal neuromuscular blocking agent by van den Broek, L, Wierda, J M, Smeulers, N J, Proost, J H

“…We have evaluated in 10 anaesthetized patients the time course of action, infusion requirements, reversibility and pharmacokinetics of Org 9487. Org 9487 was…”
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Time course of action and intubating conditions following vecuronium, rocuronium and mivacurium by Wierda, J M, Hommes, F D, Nap, H J, van den Broek, L

“…The purpose of this study was to compare the time course of action and tracheal intubating conditions of vecuronium, rocuronium and mivacurium in anaesthetised…”
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Rapacuronium 2.0 or 2.5 mg kg−1 for rapid-sequence induction: comparison with succinylcholine 1.0 mg kg−1 by Blobner, M., Mirakhur, R.K., Wierda, J.M.K.H., Wright, P.M.C., Olkkola, K.T., Debaene, B., Pendeville, P., Engbæk, J., Rietbergen, H., Sparr, H.J.

“…The purpose of this nine-centre study in 602 patients was to show that the frequency of acceptable intubating conditions after rapacuronium 2.0 or 2.5 mg kg−1…”
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Pharmacokinetics and pharmacokinetic-dynamic modelling of rocuronium in infants and children by Wierda, J M, Meretoja, O A, Taivainen, T, Proost, J H

“…We have determined the pharmacokinetics and pharmacokinetic-pharmacodynamic relationship of rocuronium in infants and children. We studied infants (n = 5,…”
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Dose-response and concentration-response relation of rocuronium infusion during propofol-nitrous oxide and isoflurane-nitrous oxide anaesthesia by Kansanaho, M, Olkkola, K T, Wierda, J M

“…The dose-response and concentration-response relation of rocuronium infusion was studied in 20 adult surgical patients during propofol-nitrous oxide and…”
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Pharmacokinetics of rocuronium after bolus and continuous infusion during halothane anaesthesia by McCoy, E P, Mirakhur, R K, Maddineni, V R, Wierda, J M, Proost, J H

“…We have studied the pharmacokinetics of a single bolus of rocuronium (Org 9426), followed by an infusion, in eight patients during anaesthesia with halothane…”
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Stabilization and stability of twitch force during mechanomyography of the adductor pollicis muscle by VAN SANTEN, G, FIDLER, V, WIERDA, J. M. K. H

“…In order to study the stabilization time, the increase in twitch force during stabilization and the maintenance of stability during mechanomyography of the…”
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