Search Results - "Wierczeiko, Anna"
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Selective RNA pseudouridinylation in situ by circular gRNAs in designer organelles
Published in Nature communications (24-10-2024)“…RNA modifications play a pivotal role in the regulation of RNA chemistry within cells. Several technologies have been developed with the goal of using RNA…”
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Acitretin reverses early functional network degradation in a mouse model of familial Alzheimer’s disease
Published in Scientific reports (23-03-2021)“…Aberrant activity of local functional networks underlies memory and cognition deficits in Alzheimer’s disease (AD). Hyperactivity was observed in microcircuits…”
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Common miRNA Patterns of Alzheimer's Disease and Parkinson's Disease and Their Putative Impact on Commensal Gut Microbiota
Published in Frontiers in neuroscience (05-03-2019)“…With the rise of Next-Generation-Sequencing (NGS) methods, Micro-RNAs (miRNAs) have achieved an important position in the research landscape and have been…”
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4
Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor
Published in Frontiers in synaptic neuroscience (08-04-2021)“…Brain homeostasis is the dynamic equilibrium whereby physiological parameters are kept actively within a specific range. The homeostatic range is not fixed and…”
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Voluntary Wheel Running Did Not Alter Gene Expression in 5xfad Mice, but in Wild-Type Animals Exclusively after One-Day of Physical Activity
Published in Cells (Basel, Switzerland) (20-03-2021)“…Physical activity is considered a promising preventive intervention to reduce the risk of developing Alzheimer's disease (AD). However, the positive effect of…”
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Leveraging interindividual variability in threat conditioning of inbred mice to model trait anxiety
Published in PLoS biology (28-05-2024)“…Trait anxiety is a major risk factor for stress-induced and anxiety disorders in humans. However, animal models accounting for the interindividual variability…”
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ViNe-Seg: deep-learning-assisted segmentation of visible neurons and subsequent analysis embedded in a graphical user interface
Published in Bioinformatics (Oxford, England) (29-03-2024)“…Abstract Summary Segmentation of neural somata is a crucial and usually the most time-consuming step in the analysis of optical functional imaging of neuronal…”
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A Call for Gene Expression Analysis in Whole Blood of Patients With Rheumatoid Arthritis (RA) as a Biomarker for RA-Associated Interstitial Lung Disease
Published in Journal of rheumatology (01-02-2024)“…Rheumatoid arthritis (RA)-associated interstitial lung disease (ILD) is one of the most common and prognostic organ manifestations of RA. Therefore, to allow…”
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NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis
Published in Bioinformatics (Oxford, England) (01-08-2023)“…Abstract Summary Oxford Nanopore Technologies’ (ONT) sequencing platform offers an excellent opportunity to perform real-time analysis during sequencing. This…”
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