Search Results - "Wierød, L."

Activation of the p53-p21 pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes by Wierød, L, Rosseland, C M, Lindeman, B, Oksvold, M P, Grøsvik, H, Skarpen, E, Huitfeldt, H S

“…p53 plays a major role in the prevention of tumor development. It responds to a range of potentially oncogenic stresses by activating protective mechanisms,…”
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CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes by Wierød, L., Rosseland, C. M., Lindeman, B., Oksvold, M. P., Grøsvik, H., Skarpen, E., Huitfeldt, H. S.

“…  Introduction/Objectives: Cell cycle progression is driven by the coordinated regulation of cyclin‐dependent kinases (CDKs). In response to mitogenic…”
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Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF by Oksvold, Morten P., Skarpen, Ellen, Wierød, Lene, Paulsen, Ragnhild E., Huitfeldt, Henrik S.

“…The rapid internalization of receptor tyrosine kinases after ligand binding has been assumed to be a negative modulation of signal transduction. However,…”
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Saponin permeabilization of rough microsomes from rat liver reveals a novel prothrombin pool by Tollefsen, Stig, Wierød, Lene, Skotte, Anne, Rob, Jan A, Helgeland, Liv

“…Saponin permeabilization of rough microsomes in the presence of high salt revealed a novel pool of prothrombin associated by ionic interactions to the…”
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Activation of the p53–p21Cip1 pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes by Wierød, L, Rosseland, C M, Lindeman, B, Oksvold, M P, Grøsvik, H, Skarpen, E, Huitfeldt, H S

“…p53 plays a major role in the prevention of tumor development. It responds to a range of potentially oncogenic stresses by activating protective mechanisms,…”
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Prevalence of cholesteryl ester storage disease among hypercholesterolemic subjects and functional characterization of mutations in the lysosomal acid lipase gene by Vinje, Terje, Wierød, Lene, Leren, Trond P., Strøm, Thea Bismo

“…Lysosomal acid lipase hydrolyzes cholesteryl esters and triglycerides contained in low density lipoprotein. Patients who are homozygous or compound…”
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Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes by ROSSELAND, Carola M, WIERØD, Lene, OKSVOLD, Morten P, WERNER, Heidi, ØSTVOLD, Anne Carine, THORESEN, G. Hege, PAULSEN, Ragnhild E, HUITFELDT, Henrik S, SKARPEN, Ellen

“…Reactive oxygen species (ROS) are implicated in tissue damage causing primary hepatic dysfunction following ischemia/reperfusion injury and during inflammatory…”
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Activation of the p53-[p21.sub.Cip1] pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes by Wierod, L, Rooseland, C.M, Linderman, B, Oksvold, M.P, Grosvik, H, Skarpen, E, Huitfeldt, H.S

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Alteration of G1 cell-cycle protein expression and induction of p53 but not p21/waf1 by the DNA-modifying carcinogen 2-acetylaminofluorene in growth-stimulated hepatocytes in vitro by Lindeman, Birgitte, Skarpen, Ellen, Thoresen, G. Hege, Christoffersen, Thoralf, Wierød, Lene, Madshus, Inger Helene, Huitfeldt, Henrik S.

“…2‐Acetylaminofluorene (AAF) is a potent tumor promoter in rat liver carcinogenesis models. In the resistant hepatocyte model, AAF is combined with a growth…”
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Why is dioxin harmful? by Huitfeldt, H S, Lindeman, B, Skarpen, E, Oksvold, M P, Wierød, L

“…The scandal in Belgium last spring has drawn attention to the environmental hazards of dioxins. Previous production of pesticides and widespread combustion of…”
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