Search Results - "Wiemer, C."
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Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study
Published in Critical care medicine (01-05-2017)“…OBJECTIVES:To prospectively validate that the inability to decrease procalcitonin levels by more than 80% between baseline and day 4 is associated with…”
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Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review
Published in Frontiers in immunology (20-01-2022)“…Lipid rafts, also known as microdomains, are important components of cell membranes and are enriched in cholesterol, glycophospholipids and receptors. They are…”
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3
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK–NF-κB signaling mediated inflammation
Published in Nature communications (17-04-2019)“…Macrophage-orchestrated, low-grade chronic inflammation plays a pivotal role in obesity and atherogenesis. However, the underlying regulatory mechanisms remain…”
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Should I vote-by-mail or in person? The impact of COVID-19 risk factors and partisanship on vote mode decisions in the 2020 presidential election
Published in PloS one (15-09-2022)“…While the evidence is clear that 2020 voters shifted away from Election Day voting in favor of vote-by-mail and early voting, we know very little about how…”
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MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation
Published in International journal of legal medicine (01-05-2010)“…MicroRNAs (miRNAs) are non-protein coding molecules with important regulatory functions; many have tissue-specific expression patterns. Their very small size…”
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MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines
Published in PloS one (07-05-2019)“…MicroRNAs (miRNAs) regulate gene expression post-transcriptionally. In this way they might influence whether a cell is sensitive or resistant to a certain…”
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Major vault protein (MVP) suppresses aging- and estrogen deficiency-related bone loss through Fas-mediated apoptosis in osteoclasts
Published in Cell death & disease (13-09-2023)“…Osteoclasts (OCs), derived from monocyte/macrophage lineage, are key orchestrators in bone remodeling. Targeting osteoclast apoptosis is a promising approach…”
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Chemical, structural and magnetic properties of the Fe/Sb2Te3 interface
Published in Journal of magnetism and magnetic materials (15-03-2019)“…•Ferromagnetism preserved at the interface between Fe and granular Sb2Te3 deposited by MOCVD.•Preferential Fe–Te bonding in Fe/Sb2Te3…”
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Recruitment of the major vault protein by InlK: a Listeria monocytogenes strategy to avoid autophagy
Published in PLoS pathogens (01-08-2011)“…L. monocytogenes is a facultative intracellular bacterium responsible for listeriosis. It is able to invade, survive and replicate in phagocytic and…”
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Ozone-Based Atomic Layer Deposition of Alumina from TMA: Growth, Morphology, and Reaction Mechanism
Published in Chemistry of materials (08-08-2006)“…We examine the effect of growth temperature in the 150−300 °C range on the structural and morphological properties of Al2O3 films deposited using atomic layer…”
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Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes
Published in Nature communications (05-07-2019)“…Ttriple-negative breast cancer (TNBC) is an aggressive and highly metastatic breast cancer subtype. Enhanced TNBC cell motility is a prerequisite of TNBC cell…”
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Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2008)“…In this study, we quantified 249 mature micro-RNA (miRNA) transcripts in estrogen receptor-positive (ER⁺) primary breast tumors of patients with lymph…”
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Non-Coding RNAs, a Novel Paradigm for the Management of Gastrointestinal Stromal Tumors
Published in International journal of molecular sciences (22-09-2020)“…Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal malignancies found in the gastrointestinal tract. At a molecular level, most GISTs are…”
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14
Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump
Published in Blood (01-11-2004)“…Imatinib mesylate (STI571), a potent tyrosine kinase inhibitor, is successfully used in the treatment of chronic myelogenous leukemia and gastrointestinal…”
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Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors
Published in PloS one (15-08-2017)“…Malignant peripheral nerve sheath tumors (MPNST) are rare, highly aggressive sarcomas that can occur spontaneously or from pre-existing plexiform neurofibromas…”
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Atomic Layer Deposition of hexagonal ErFeO3 thin films on SiO2/Si
Published in Thin solid films (01-04-2016)“…Hexagonal orthoferrite h-ErFeO3 thin films are synthesized by Atomic Layer Deposition on SiO2(100nm)/Si substrate, followed by rapid thermal annealing at…”
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Metabolite profiling identifies candidate markers reflecting the clinical adaptations associated with Roux-en-Y gastric bypass surgery
Published in PloS one (19-11-2009)“…Roux-en-Y gastric bypass (RYGB) surgery is associated with weight loss, improved insulin sensitivity and glucose homeostasis, and a reduction in co-morbidities…”
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Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis
Published in Cancers (12-06-2019)“…Uveal melanoma (UM) is the most frequently found primary intra-ocular tumor in adults. It is a highly aggressive cancer that causes metastasis-related…”
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Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review
Published in Frontiers in oncology (17-05-2019)“…Desmoid-type fibromatosis (DTF) is a rare, soft tissue tumor of mesenchymal origin which is characterized by local infiltrative growth behavior. Besides "wait…”
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Advanced protective coatings for reflectivity enhancement by low temperature atomic layer deposition of HfO2 on Al surfaces for micromirror applications
Published in Sensors and actuators. A. Physical. (15-10-2018)“…•ALD HfO2/ PECVD SiO2 stack has been proposed for protection and reflectance enhancement of Al micromirrors.•The used simulation methodology allows to design…”
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