Search Results - "Wielgosz, Robert"
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Metrological framework to support accurate, reliable, and reproducible nucleic acid measurements
Published in Analytical and bioanalytical chemistry (01-01-2022)“…Nucleic acid analysis is used in many areas of life sciences such as medicine, food safety, and environmental monitoring. Accurate, reliable measurements of…”
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Impurity determination for hepcidin by liquid chromatography-high resolution and ion mobility mass spectrometry for the value assignment of candidate primary calibrators
Published in Analytical and bioanalytical chemistry (01-04-2017)“…In metrology institutes, the state-of-the-art for purity analysis of peptides/proteins mainly addresses short and unfolded peptides. Important developments are…”
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Implementing a Reference Measurement System for C-Peptide: Successes and Lessons Learned
Published in Clinical chemistry (Baltimore, Md.) (01-09-2017)“…Assessment of endogenous insulin secretion by measuring C-peptide concentrations is widely accepted. Recent studies have shown that preservation of even small…”
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Structurally related peptide impurity identification and accurate quantification for synthetic oxytocin by liquid chromatography–high-resolution mass spectrometry
Published in Analytical and bioanalytical chemistry (01-03-2021)“…Oxytocin (OXT) is an important peptide that is mainly used as a therapeutic drug to induce labor or strengthen uterine contractions, or to control bleeding…”
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The BIPM Mycotoxin Metrology Capacity Building and Knowledge Transfer Program: Accurate Characterization of a Pure Aflatoxin B 1 Material to Avoid Calibration Errors
Published in Journal of AOAC International (01-11-2019)“…The contamination of food and feed by mycotoxins, Aflatoxin B (AfB ) being one of the most prominent examples, is of imminent concern to many countries…”
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Identification and accurate quantification of structurally related peptide impurities in synthetic human C-peptide by liquid chromatography–high resolution mass spectrometry
Published in Analytical and bioanalytical chemistry (01-08-2018)“…Peptides are an increasingly important group of biomarkers and pharmaceuticals. The accurate purity characterization of peptide calibrators is critical for the…”
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Second harmonic generation on crystalline organic nanoclusters under extreme nanoconfinement in functionalized silica–benzil composites
Published in Scientific reports (19-06-2023)“…We demonstrate a series of organic–inorganic nanocomposite materials combining the mesoporous silica ( PS ) and benzil ( BZL ) nanocrystals embedded into its…”
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Ozone Cross-Section Measurement by Gas Phase Titration
Published in Analytical chemistry (Washington) (01-11-2016)“…Elevated values of ground-level ozone damage health, vegetation, and building materials and are the subject of air quality regulations. Levels are monitored by…”
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An SI-traceable reference material for virus-like particles
Published in iScience (20-05-2022)“…A reference material for virus-like particles traceable to the International System of Units (Système International d'Unités – the SI) is reported. The…”
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Accurate Fourier Transform Infrared (FT-IR) Spectroscopy Measurements of Nitrogen Dioxide (NO2) and Nitric Acid (HNO3) Calibrated with Synthetic Spectra
Published in Applied spectroscopy (01-10-2013)“…A novel method for determining the accuracy of laboratory-based measurements of nitrogen dioxide (NO2) and nitric acid (HNO3) mole fractions using Fourier…”
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Simultaneous determination of various cardiac glycosides by liquid chromatography–hybrid mass spectrometry for the purity assessment of the therapeutic monitored drug digoxin
Published in Journal of Chromatography A (02-07-2010)“…A high performance liquid chromatography–hybrid tandem mass spectrometry (LC–MS n ) method utilising electrospray ionisation has been developed and implemented…”
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Mass Balance Method for the SI Value Assignment of the Purity of Organic Compounds
Published in Analytical chemistry (Washington) (19-03-2013)“…A mass balance method is described for determining the mass fraction of the main component of a high purity organic material. The resulting assigned value is…”
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Report of the CCU/CCQM Workshop on “The Metrology of Quantities Which Can Be Counted”
Published in Metrology (04-09-2023)“…This article provides a report of the recent workshop on “The metrology of quantities which can be counted” organised jointly by the International Committee…”
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Calibration Strategies for FT-IR and Other Isotope Ratio Infrared Spectrometer Instruments for Accurate δ13C and δ18O Measurements of CO2 in Air
Published in Analytical chemistry (Washington) (21-03-2017)“…This paper describes calibration strategies in laboratory conditions that can be applied to ensure accurate measurements of the isotopic composition of the CO2…”
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Implementing metrological traceability of C-reactive protein measurements: consensus summary from the Joint Committee for Traceability in Laboratory Medicine Workshop
Published in Clinical chemistry and laboratory medicine (28-08-2023)“…The Joint Committee for Traceability in Laboratory Medicine (JCTLM) currently lists the secondary commutable certified reference material (CRM) ERM DA-474/IFCC…”
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International Activities in Metrology in Chemistry
Published in Chimia (01-10-2009)“…In today's economy goods and information are being exchanged globally, international travel is commonplace as is the cross-boarder transport of livestock and…”
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Reliable measurement of multiplexed biomarker panel of RNA transcripts
Published in Biomolecular detection and quantification (01-06-2016)Get full text
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State-of-the-art and trends for the SI traceable value assignment of the purity of peptides using the model compound angiotensin I
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-04-2018)“…Accurate diagnosis, monitoring and treatment are cornerstones of a healthcare system and require reliable measurements. The traceability of measurement results…”
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High-Order Harmonics and Photoluminescence in Azo-Phenylthiophene Derivatives
Published in Journal of physical chemistry. C (21-11-2024)“…This paper presents the linear and nonlinear optical (NLO) properties of two donor–acceptor organic materials, namely,…”
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