Search Results - "Wieland, T."
-
1
Assembly of COPI and COPII Vesicular Coat Proteins on Membranes
Published in Annual review of biophysics (20-05-2018)“…In eukaryotes, distinct transport vesicles functionally connect various intracellular compartments. These carriers mediate transport of membranes for the…”
Get full text
Journal Article -
2
Proteomic Profiling of Mammalian COPII and COPI Vesicles
Published in Cell reports (Cambridge) (02-01-2019)“…Intracellular transport and homeostasis of the endomembrane system in eukaryotic cells depend on the formation and fusion of vesicular carriers. Coat protein…”
Get full text
Journal Article -
3
The HIV Lipidome: A Raft with an Unusual Composition
Published in Proceedings of the National Academy of Sciences - PNAS (21-02-2006)“…The lipids of enveloped viruses play critical roles in viral morphogenesis and infectivity. They are derived from the host membranes from which virus budding…”
Get full text
Journal Article -
4
Sec24C/D-isoform-specific sorting of the preassembled ER-Golgi Q-SNARE complex
Published in Molecular biology of the cell (01-09-2016)“…Secretory proteins are exported from the endoplasmic reticulum in COPII vesicles. SNARE proteins-core machinery for membrane fusion-are incorporated into COPII…”
Get full text
Journal Article -
5
A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4
Published in The EMBO journal (16-06-2010)“…Cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes, has pivotal functions for the cellular energy…”
Get full text
Journal Article -
6
The BAR Domain Protein Arfaptin-1 Controls Secretory Granule Biogenesis at the trans-Golgi Network
Published in Developmental cell (16-10-2012)“…BAR domains can prevent membrane fission through their ability to shield necks of budding vesicles from fission-inducing factors. However, the physiological…”
Get full text
Journal Article -
7
genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria
Published in The Journal of cell biology (23-02-2009)“…Prohibitin ring complexes in the mitochondrial inner membrane regulate cell proliferation as well as the dynamics and function of mitochondria. Although…”
Get full text
Journal Article -
8
GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation
Published in Nature communications (10-01-2019)“…COPI is a key mediator of protein trafficking within the secretory pathway. COPI is recruited to the membrane primarily through binding to Arf GTPases, upon…”
Get full text
Journal Article -
9
The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes
Published in PloS one (12-08-2022)“…Protein S-palmitoylation, the addition of a long-chain fatty acid to target proteins, is among the most frequent reversible protein modifications in Metazoa,…”
Get full text
Journal Article -
10
Protein Sorting by Transport Vesicles
Published in Science (American Association for the Advancement of Science) (12-04-1996)“…Eukaryotic life depends on the spatial and temporal organization of cellular membrane systems. Recent advances in understanding the machinery of vesicle…”
Get full text
Journal Article -
11
Heterozygosity for ARID2 loss-of-function mutations in individuals with a Coffin–Siris syndrome-like phenotype
Published in Human genetics (01-03-2017)“…Chromatin remodeling is a complex process shaping the nucleosome landscape, thereby regulating the accessibility of transcription factors to regulatory regions…”
Get full text
Journal Article -
12
Journeys through the Golgi--taking stock in a new era
Published in The Journal of cell biology (16-11-2009)“…The Golgi apparatus is essential for protein sorting and transport. Many researchers have long been fascinated with the form and function of this organelle…”
Get full text
Journal Article -
13
Arf1-GTP-induced Tubule Formation Suggests a Function of Arf Family Proteins in Curvature Acquisition at Sites of Vesicle Budding
Published in The Journal of biological chemistry (10-10-2008)“…ADP-ribosylation factor (Arf) and related small GTPases play crucial roles in membrane traffic within the exo- and endocytic pathways. Arf proteins in their…”
Get full text
Journal Article -
14
Several ADP-ribosylation Factor (Arf) Isoforms Support COPI Vesicle Formation
Published in The Journal of biological chemistry (14-10-2011)“…Newly synthesized proteins and lipids are transported in vesicular carriers along the secretory pathway. Arfs (ADP-ribosylation factors), a family of highly…”
Get full text
Journal Article -
15
Identification of new TRIP12 variants and detailed clinical evaluation of individuals with non-syndromic intellectual disability with or without autism
Published in Human genetics (01-02-2017)“…The ubiquitin pathway is an enzymatic cascade including activating E1, conjugating E2, and ligating E3 enzymes, which governs protein degradation and sorting…”
Get full text
Journal Article -
16
Probing HIV-1 Membrane Liquid Order by Laurdan Staining Reveals Producer Cell-dependent Differences
Published in The Journal of biological chemistry (14-08-2009)“…Viruses acquire their envelope by budding from a host cell membrane, but viral lipid composition may differ from that of the budding membrane. We have…”
Get full text
Journal Article -
17
Additional notes on the nesting biology of the Blackish Tapaculo (Scytalopus latrans)
Published in The Wilson journal of ornithology (01-12-2019)“…Tapaculo (Scytalopus) nests are difficult to find because they are well-hidden in cavities, hence, there is limited information available for this genus. We…”
Get full text
Journal Article -
18
Quantitative Analysis of Biological Membrane Lipids at the Low Picomole Level by Nano-Electrospray Ionization Tandem Mass Spectrometry
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-1997)“…Nano-electrospray tandem mass spectrometry allows qualitative and quantitative analysis of complex membrane lipid mixtures at the subpicomole level. We have…”
Get full text
Journal Article -
19
Sphingomyelin-enriched microdomains at the Golgi complex
Published in Molecular biology of the cell (01-06-2001)“…Sphingomyelin- and cholesterol-enriched microdomains can be isolated as detergent-resistant membranes from total cell extracts (total-DRM). It is generally…”
Get full text
Journal Article -
20
Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes
Published in Biochemical journal (01-08-2004)“…Morphological analysis of a conditional yeast mutant in acetyl-CoA carboxylase acc1ts/mtr7, the rate-limiting enzyme of fatty acid synthesis, suggested that…”
Get full text
Journal Article