Search Results - "Wieland, D. M"

In vivo mapping of cholinergic terminals in normal aging, Alzheimer's disease, and Parkinson's disease by Kuhl, D E, Minoshima, S, Fessler, J A, Frey, K A, Foster, N L, Ficaro, E P, Wieland, D M, Koeppe, R A

“…To map presynaptic cholinergic terminal densities in normal aging (n = 36), Alzheimer's disease (AD) (n = 22), and Parkinson's disease (PD) (n = 15), we…”
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Cardiac sympathetic dysinnervation in diabetes : Implications for enhanced cardiovascular risk by STEVENS, M. J, RAFFEL, D. M, ALLMAN, K. C, DAYANIKLI, F, FICARO, E, SANDFORD, T, WIELAND, D. M, PFEIFER, M. A, SCHWAIGER, M

“…Regional cardiac sympathetic hyperactivity predisposes to malignant arrhythmias in nondiabetic cardiac disease. Conversely, however, cardiac sympathetic…”
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Assessment of cardiac sympathetic nerve integrity with positron emission tomography by Raffel, David M, Wieland, Donald M

“…The autonomic nervous system plays a critical role in the regulation of cardiac function. Abnormalities of cardiac innervation have been implicated in the…”
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Evaluation of sympathetic nerve terminals with [11C]epinephrine and [11C]hydroxyephedrine and positron emission tomography by MÜNCH, G, NGUYEN, N. T. B, NEKOLLA, S, ZIEGLER, S, MUZIK, O, CHAKRABORTY, P, WIELAND, D. M, SCHWAIGER, M

“…The goal of the present study was to directly compare the new radiopharmaceutical agent [(11)C]epinephrine (EPI) with [(11)C]hydroxyephedrine (HED) through the…”
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Scintigraphic Assessment of Regionalized Defects in Myocardial Sympathetic Innervation and Blood Flow Regulation in Diabetic Patients With Autonomic Neuropathy by Stevens, Martin J, Dayanikli, Firat, Raffel, David M, Allman, Kevin C, Sandford, Tracy, Feldman, Eva L, Wieland, Donald M, Corbett, James, Schwaiger, Marcus

“…Objectives. This study sought to evaluate whether regional sympathetic myocardial denervation in diabetes is associated with abnormal myocardial blood flow…”
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Noninvasive evaluation of sympathetic nervous system in human heart by positron emission tomography by SCHWAIGER, M, KALFF, V, ROSENSPIRE, K, HAKA, M. S, MOLINA, E, HUTCHINS, G. D, DEEB, M, WOLFE, E JR, WIELAND, D. M

“…The noninvasive functional characterization of the cardiac sympathetic nervous system by imaging techniques may provide important pathophysiological…”
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Synthesis and Preliminary Evaluation of Carbon-11-Meta-Hydroxyephedrine: A False Transmitter Agent for Heart Neuronal Imaging by Rosenspire, Karen C, Haka, Michael S, Van Dort, Marcian E, Jewett, Douglas M, Gildersleeve, David L, Schwaiger, Markus, Wieland, Donald M

“…Carbon-11-meta-hydroxyephedrine is a new radiotracer developed for mapping the sympathetic nerves of the heart. Carbon-11-meta-hydroxyephedrine is synthesized…”
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Carbon-11 hydroxyephedrine with positron emission tomography for serial assessment of cardiac adrenergic neuronal function after acute myocardial infarction in humans by Allman, Kevin C., Wieland, Donald M., Muzik, Otto, Degrado, Timothy R., Wolfe, Edwin R., Schwaiger, Markus

“…Objectives. The purpose of this study was to assess the extent and reversibility of neuronal abnormalities in patients with an acute myocardial infarction…”
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Influence of Vesicular Storage and Monoamine Oxidase Activity on [11C]Phenylephrine Kinetics: Studies in Isolated Rat Heart by Raffel, David M, Wieland, Donald M

“…[11C]Phenylephrine (PHEN) is a radiolabeled analogue of norepinephrine that is transported into cardiac sympathetic nerve varicosities by the neuronal…”
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Myocardial Kinetics of Carbon-11-Meta-Hydroxyephedrine: Retention Mechanisms and Effects of Norepinephrine by DeGrado, Timothy R, Hutchins, Gary D, Toorongian, Steven A, Wieland, Donald M, Schwaiger, Markus

“…Carbon-11-labeled meta-hydroxyephedrine (HED, N-methyl-metaraminol) is a catecholamine analog developed for the PET imaging of sympathetic nerve terminals of…”
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PET Hydroxyephedrine Imaging of Neuroblastoma by Shulkin, Barry L, Wieland, Donald M, Baro, Marie E, Ungar, David R, Mitchell, Deanna S, Dole, Mukund G, Rawwas, Jawhar B, Castle, Valerie P, Sisson, James C, Hutchinson, Raymond J

“…The goals of this investigation were to characterize the uptake of 11C-hydroxyephedrine (HED) in neuroblastoma and to determine the feasibility and potential…”
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PET Scanning with Hydroxyephedrine: An Approach to the Localization of Pheochromocytoma by Shulkin, Barry L, Wieland, Donald M, Schwaiger, Markus, Thompson, Norman W, Francis, Isaac R, Haka, Michael S, Rosenspire, Karen C, Shapiro, Brahm, Sisson, James C, Kuhl, David E

“…Pheochromocytomas are potentially curable causes of hypertension. These tumors are currently located by functional imaging with meta-iodobenzylguanidine…”
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Noninvasive assessment of cardiac diabetic neuropathy by carbon-11 hydroxyephedrine and positron emission tomography by Allman, Kevin C., Stevens, Martin J., Wieland, Donald M., Hutchins, Gary D., Wolfe, Edwin R., Greene, Douglas A., Schwaiger, Markus

“…Objectives. The purpose of this investigation was to evaluate the sympathetic nervous system of the heart by positron emission tomographic (PET) imaging in…”
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In Vivo Mapping of Cholinergic Neurons in the Human Brain Using SPECT and IBVM by Kuhl, David E, Koeppe, Robert A, Fessler, Jeffrey A, Minoshima, Satoshi, Ackermann, Robert J, Carey, James E, Gildersleeve, David L, Frey, Kirk A, Wieland, Donald M

“…In the search for an in vivo marker of cholinergic neuronal integrity, we extended to human use the tracer (-)-5-[123I]iodobenzovesamicol (IBVM). IBVM, an…”
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Metaiodobenzylguanidine as an Index of the Adrenergic Nervous System Integrity and Function by Sisson, J.C, Wieland, D.M, Sherman, P, Mangner, T.J, Tobes, M.C, Jacques, S., Jr

“…The radiopharmaceutical, metaiodobenzylguanidine (MIBG) acts as an analog of norepinephrine (NE). Experiments in rats were carried out to determine how closely…”
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Metaiodobenzylguanidine to Map Scintigraphically the Adrenergic Nervous System in Man by Sisson, J.C, Shapiro, B, Meyers, L, Mallette, S, Mangner, T.J, Wieland, D.M, Glowniak, J.V, Sherman, P, Beierwaltes, W.H

“…Metaiodobenzylguanidine (MIBG) localizes in adrenergic neurons; MIBG labeled with 123I then serves as an analog of norepinephrine, and concentrations of…”
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Clinical Evaluation of Carbon-11-Phenylephrine: MAO-Sensitive Marker of Cardiac Sympathetic Neurons by Raffel, David M, Corbett, James R, del Rosario, Renato B, Gildersleeve, David L, Chiao, Ping-Chun, Schwaiger, Markus, Wieland, Donald M

“…The sympathomimetic drug phenylephrine recently has been labeled with 11C for use in PET studies of cardiac sympathetic innervation. Previous reports using…”
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Sensitivity of [11C] Phenylephrine Kinetics to Monoamine Oxidase Activity in Normal Human Heart by Raffel, David M, Corbett, James R, del Rosario, Renato B, Mukhopadhyay, Sunil K, Gildersleeve, David L, Rose, Patti, Wieland, Donald M

“…Phenylephrine labeled with 11C was developed as a radiotracer for imaging studies of cardiac sympathetic nerves with PET. A structural analog of…”
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Vesamicol Receptor Mapping of Brain Cholinergic Neurons with Radioiodine- Labeled Positional Isomers of Benzovesamicol by Jung, Yong-Woon, Frey, Kirk A, Mulholland, G. Keith, del Rosario, Renato, Sherman, Phillip S, Raffel, David M, Van Dort, Marcian E, Kuhl, David E, Gildersleeve, David L, Wieland, Donald M

“…Alzheimer's disease is characterized by progressive cerebral cholinergic neuronal degeneration. Radiotracer analogs of benzovesamicol, which bind with high…”
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The Impact of Signaling on the 2022 to 2023 Orthopaedic Residency Application Cycle: A Survey of Incoming Residents by Tarapore, Rae, Wieland, Mark D, Haislup, Brett, Imbergamo, Casey, McCormick, Brian, Castillo, Wilfrido, Boucher, Henry

“…During the 2022 to 2023 orthopaedic surgery residency application cycle, "signaling" was added, allowing applicants to communicate strong interest to 30…”
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