Search Results - "Wiegand, Volker"

Specification of the cholesterol interaction with the oxytocin receptor using a chimeric receptor approach by Wiegand, Volker, Gimpl, Gerald

“…The oxytocin receptor specifically requires cholesterol to maintain and stabilize its high-affinity agonist binding. Here, we applied a receptor chimeric…”
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A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer by Sebastian, Martin, Schröder, Andreas, Scheel, Birgit, Hong, Henoch S., Muth, Anke, von Boehmer, Lotta, Zippelius, Alfred, Mayer, Frank, Reck, Martin, Atanackovic, Djordje, Thomas, Michael, Schneller, Folker, Stöhlmacher, Jan, Bernhard, Helga, Gröschel, Andreas, Lander, Thomas, Probst, Jochen, Strack, Tanja, Wiegand, Volker, Gnad-Vogt, Ulrike, Kallen, Karl-Josef, Hoerr, Ingmar, von der Muelbe, Florian, Fotin-Mleczek, Mariola, Knuth, Alexander, Koch, Sven D.

“…CV9201 is an RNActive ® -based cancer immunotherapy encoding five non-small cell lung cancer-antigens: New York esophageal squamous cell carcinoma-1, melanoma…”
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Angiographic predictors of recurrence of restenosis after Wiktor stent implantation in native coronary arteries by DeJaegere, Peter, Serruys, Patrick W., Bertrand, Michel, Wiegand, Volker, Marquis, Jean Francois, Vrolicx, Matthias, Piessens, Jan, Valeix, Bernard, Kober, Gisbert, Bonnier, Hans, Rutsch, Wolfgang, Uebis, Rainer

“…Intracoronary stenting has been proposed as an adjunct to balloon angioplasty to improve the immediate and long-term results. However, late luminal narrowing…”
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Distinct transcriptional changes in non-small cell lung cancer patients associated with multi-antigenic RNActive® CV9201 immunotherapy by Hong, Henoch S., Koch, Sven D., Scheel, Birgit, Gnad-Vogt, Ulrike, Schröder, Andreas, Kallen, Karl-Josef, Wiegand, Volker, Backert, Linus, Kohlbacher, Oliver, Hoerr, Ingmar, Fotin-Mleczek, Mariola, Billingsley, James M.

“…We recently completed a phase I/IIa trial of RNActive® CV9201, a novel mRNA-based therapeutic vaccine targeting five tumor-associated antigens in non-small…”
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Beneficial effects of long-term diltiazem treatment in dilated cardiomyopathy by Figulla, Hans R., Rechenberg, J:̈org V., Wiegand, Volker, Soballa, Reinhild, Kreuzer, Heinrich

“…There is increasing evidence that chronic enhanced exogenous or endogenous catecholamine stimulation in patients with dilated cardiomyopathy may worsen…”
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Cholesterol and steroid hormones: modulators of oxytocin receptor function by Gimpl, Gerald, Wiegand, Volker, Burger, Katja, Fahrenholz, Falk

“…The function and physiological regulation of the oxytocin-receptor system is strongly steroid-dependent. This is, unexpectedly, only partially reflected by the…”
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Messenger RNA vaccination and B-cell responses in NSCLC patients by Sebastian, Martin, von Boehmer, Lotta, Zippelius, Alfred, Mayer, Frank, Reck, Martin, Atanackovic, Djordje, Thomas, Michael, Schneller, Folker, Stoehlmacher-Williams, Jan, Goekkurt, Eray, Bernhard, Helga, Groeschel, Andreas, Scheel, Birgit, Koch, Sven D., Lander, Thomas, Rippin, Gerd, Wiegand, Volker, Gnad-Vogt, Ulrike Senta, Kallen, Karl-Josef, Knuth, Alexander

“…Abstract only 2573^ Background: Vaccination with mRNA is a novel technology in cancer immunotherapy. CV9201 consists of self-adjuvanted mRNA molecules…”
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Transport of plasma membrane‐derived cholesterol and the function of Niemann‐Pick C1 protein by Wiegand, Volker, Chang, Ta‐Yuan, Strauss, Jerome F., Fahrenholz, Falk, Gimpl, Gerald

“…ABSTRACT To visualize the intracellular transport of plasma membrane‐derived cholesterol under physiological and pathophysiological conditions, a novel…”
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Recoil following Wiktor stent implantation for restenotic lesions of coronary arteries by de Jaegere, P, Serruys, P W, van Es, G A, Bertrand, M, Wiegand, V, Marquis, J F, Vrolicx, M, Piessens, J, Valeix, B, Kober, G

“…The purpose of this study was to determine acute recoil of the vessel wall immediately after Wiktor stent implantation in native coronary arteries of 77…”
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Molecular modelling study of the role of cholesterol in the stimulation of the oxytocin receptor by Politowska, E, Kaźmierkiewicz, R, Wiegand, V, Fahrenholz, F, Ciarkowski, J

“…Cholesterol, an integral component of membranes in Eucaryota, is a modifier of membrane properties. In vivo studies have demonstrated that cholesterol can also…”
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Low-molecular-weight heparin reduces neointimal proliferation after coronary stent implantation in hypercholesterolemic minipigs by BUCHWALD, A. B, UNTERBERG, C, NEBENDAHL, K, GRÖNE, H.-J, WIEGAND, V

“…Intracoronary stents have been suggested as a method of reducing the restenosis rate after balloon angioplasty. Proliferation of vascular smooth muscle cells…”
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Molecular approaches to enteroviral diagnosis in idiopathic cardiomyopathy and myocarditis by Tracy, Steven, Wiegand, Volker, McManus, Bruce, Gauntt, Charles, Pallansch, Mark, Beck, Melinda, Chapman, Nora

“…Enteroviruses are thought to be etiologic agents in some cases of human myocarditis and dilated cardiomyopathy. Murine models of acute coxsackievirus E3…”
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Wiktor stent implantation in patients with restenosis following balloon angioplasty of a native coronary artery by de Jaegere, Peter P., Serruys, Patrick W., Bertrand, Michel, Wiegand, Volker, Kober, Gisbert, Marquis, Jean Francois, Valeix, Bernard, Uebis, Rainer, Piessens, Jan

“…Intracoronary stenting has been introduced as an adjunct to balloon angioplasty aimed at overcoming its limitations, namely acute vessel closure and late…”
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Platelet and fibrin deposition on coronary stents in minipigs: Effect of hirudin versus heparin by Buchwald, Arnd B., Sandrock, Dirk, Unterberg, Christina, Ebbecke, Martin, Nebendahl, Klaus, Lüders, Stefan, Munz, Dieter L., Wiegand, Volker

“…Objectives. The present study was designed to test the hypothesis that the direct thrombin inhibitor hirudin is more efficient than heparin in reducing…”
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Intravascular ultrasound imaging of human coronary arteries after percutaneous transluminal angioplasty: morphologic and quantitative assessment by Werner, G S, Sold, G, Buchwald, A, Kreuzer, H, Wiegand, V

“…An intravascular ultrasound catheter system was used in patients to assess the effect of percutaneous transluminal coronary angioplasty. In 14 out of 16…”
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Autofluorescence spectroscopy using a XeCl excimer laser system for simultaneous plaque ablation and fluorescence excitation by Morguet, A J, Körber, B, Abel, B, Hippler, H, Wiegand, V, Kreuzer, H

“…Laser-induced fluorescence may be used to guide laser ablation of atherosclerotic lesions. This study was performed to evaluate arterial autofluorescence…”
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Combined atherosclerotic plaque ablation and autofluorescence spectroscopy in vitro using an excimer laser system by Morguet, Andreas J., Abel, Bernd, Hippler, Horst, Körber, Beate, Kreuzer, Heinrich, Wiegand, Volker

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Recanalization of chronic total coronary arterial occlusions by percutaneous excimer-laser and laser-assisted angioplasty by Werner, Gerald S., Buchwald, Arnd, Unterberg, Christina, Voth, Eberhard, Kreuzer, Heinrich, Wiegand, Volker

“…A low primary success and high restenosis rate after recanalization of chronic total occlusions by conventional coronary angioplasty have encouraged the…”
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Recanalization of chronic coronary occlusions by excimer-laser angioplasty by Werner, Gerald S., Buchwald, Arnd, Unterberg, Christine, Voth, Eberhard, Kreuzer, Heinrich, Wiegand, Volker

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Coronary angioplasty in patients with previous coronary artery bypass grafting by Unterberg, C, Buchwald, A, Wiegand, V, Kreuzer, H

“…Between 1982 and 1990, in 134 patients with prior coronary artery bypass grafting and recurrent angina, repeat coronary angiography and balloon angioplasty of…”
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