Search Results - "Wiedmann, Timothy S"

Evaluation of magnetic heating of asymmetric magnetite particles by Yao, Xin, Sabyrov, Kairat, Klein, Todd, Lee Penn, R., Wiedmann, Timothy S.

“…Characterization and theoretical description of relatively large (>100nm), asymmetric magnetic particles remain of interest particularly for applications to…”
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A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice by Heman-Ackah, Selena E., Juhn, Steven K., Huang, Tina C., Wiedmann, Timothy S.

“…Age-related hearing loss (ARHL) is characterized by gradual, progressive sensorineural hearing loss, which impairs communication, lending to clinical…”
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Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling by Lesnick, Alexandra, Samuels, Tina L., Seabloom, Donna, Wuertz, Beverly, Ojha, Abhilash, Seelig, Davis, Ondrey, Frank, Wiedmann, Timothy S., Hogan, Chris, Torii, Emma, Ouyang, Hui, Yan, Ke, Garcia, Guilherme J. M., Bock, Jonathan M., Johnston, Nikki

“…Objectives Approximately 25% of Americans suffer from laryngopharyngeal reflux (LPR), a disease for which no effective medical therapy exists. Pepsin is a…”
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Inhalable magnetic nanoparticles for targeted hyperthermia in lung cancer therapy by Sadhukha, Tanmoy, Wiedmann, Timothy S, Panyam, Jayanth

“…Abstract Lung cancer (specifically, non-small cell lung cancer; NSCLC) is the leading cause of cancer-related deaths in the United States. Poor response rates…”
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Pharmacokinetics of 5-fluorouracil in the hamster following inhalation delivery of lipid-coated nanoparticles by Hitzman, Cory J, Wattenberg, Lee W, Wiedmann, Timothy S

“…The inhalation delivery of 5-fluorouracil (5-FU) in lipid-coated nanoparticles (LNPs) to hamsters was evaluated to determine the feasibility for use in lung…”
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Modulating insulin signaling and trafficking at the blood-brain barrier endothelium using lipid based nanoemulsions by Wang, Lushan, Wiedmann, Timothy S., Kandimalla, Karunya K.

“…[Display omitted] •Lipid rafts regulate trafficking and signal transduction at the BBB.•SNEs but not ONEs modulate lipid raft integrity and insulin…”
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Enhancing therapeutic efficacy through designed aggregation of nanoparticles by Sadhukha, Tanmoy, Wiedmann, Timothy S, Panyam, Jayanth

“…Abstract Particle size is a key determinant of biological performance of sub-micron size delivery systems. Previous studies investigating the effect of…”
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Chemopreventive Effect of Aerosolized Polyphenon E on Lung Tumorigenesis in A/J Mice by Yan, Ying, Cook, Julie, McQuillan, Jay, Zhang, Guifang, Hitzman, Cory J., Wang, Yian, Wiedmann, Timothy S., You, Ming

“…Effective chemoprevention of lung cancer in high-risk patients through the administration of pharmacologic or nutritional agents is urgently needed. Aerosol…”
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Development of a respirable, sustained release microcarrier for 5-fluorouracil II: In vitro and in vivo optimization of lipid coated nanoparticles by Hitzman, Cory J, Elmquist, William F, Wiedmann, Timothy S

“…The release rate of 5-fluorouracil (5-FU) from lipid-coated nanoparticles (LNPs) was determined to develop a respirable delivery system for use as adjuvant…”
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Acrolein Increases the Pulmonary Tumorigenic Activity of the Tobacco-Specific Nitrosamine 4‑(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by Peterson, Lisa A., Seabloom, Donna, Smith, William E., Vevang, Karin R., Seelig, Davis M., Zhang, Lin, Wiedmann, Timothy S.

“…Tobacco smoke is a complex mixture of more than 7000 chemicals, of which many are toxic and/or carcinogenic. Many hazard assessments of tobacco have focused on…”
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Chemoprevention of cancer of the upper respiratory tract of the syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil by WATTENBERG, Lee W, WIEDMANN, Timothy S, ESTENSEN, Richard D

“…Research aimed at identifying effective chemopreventive compounds active against carcinogenesis of the upper respiratory tract (URT) has been largely…”
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Oral and Inhaled Fosamprenavir Reverses Pepsin‐Induced Damage in a Laryngopharyngeal Reflux Mouse Model by Johnston, Nikki, Samuels, Tina L., Goetz, Christopher J., Arnold, Leggy A., Smith, Brian C., Seabloom, Donna, Wuertz, Beverly, Ondrey, Frank, Wiedmann, Timothy S., Vuksanovic, Nemanja, Silvaggi, Nicholas R., MacKinnon, Alexander C., Miller, James, Bock, Jonathan, Blumin, Joel H.

“…Objective More than 20% of the US population suffers from laryngopharyngeal reflux. Although dietary/lifestyle modifications and alginates provide benefit to…”
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Inhaled Furan Selectively Damages Club Cells in Lungs of A/J Mice by Tǎbǎran, Alexandru-Flaviu, O’Sullivan, M. Gerard, Seabloom, Donna E., Vevang, Karin R., Smith, William E., Wiedmann, Timothy S., Peterson, Lisa A.

“…Furan, a possible human carcinogen, is a product of incomplete combustion and is present in cigarette smoke, engine exhaust, and processed food. Oral…”
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Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4‑Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung by Peterson, Lisa A, Oram, Marissa K, Flavin, Monica, Seabloom, Donna, Smith, William E, O’Sullivan, M. Gerard, Vevang, Karin R, Upadhyaya, Pramod, Stornetta, Alessia, Floeder, Andrew C, Ho, Yen-Yi, Zhang, Lin, Hecht, Stephen S, Balbo, Silvia, Wiedmann, Timothy S

“…Tobacco smoke is a complex mixture of chemicals, many of which are toxic and carcinogenic. Hazard assessments of tobacco smoke exposure have predominantly…”
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Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery by Layek, Buddhadev, Rahman Nirzhor, Saif S., Rathi, Sneha, Kandimalla, Karunya K., Wiedmann, Timothy S., Prabha, Swayam

“…Aldara™ (5% w / w imiquimod) topical cream is approved by the US FDA for the treatment of superficial basal cell carcinoma. However, the cream formulation…”
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Development of a respirable, sustained release microcarrier for 5-fluorouracil I: In vitro assessment of liposomes, microspheres, and lipid coated nanoparticles by Hitzman, Cory J, Elmquist, William F, Wattenberg, Lee W, Wiedmann, Timothy S

“…The release rate of 5-fluorouracil (5-FU) from liposomes, microspheres, and lipid-coated nanoparticles (LNPs) was determined by microdialysis to investigate…”
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Drug Tissue Distribution of TUDCA From a Biodegradable Suprachoroidal Implant versus Intravitreal or Systemic Delivery in the Pig Model by Olsen, Timothy W, Dyer, Roy B, Mano, Fukutaro, Boatright, Jeffrey H, Chrenek, Micah A, Paley, Daniel, Wabner, Kathy, Schmit, Jenn, Chae, Ju Byung, Sellers, Jana T, Singh, Ravinder J, Wiedmann, Timothy S

“…To determine local ocular tissue levels of the bile acid, tauroursodeoxycholic acid (TUDCA), in the pig model using oral, intravenous (IV), intravitreal…”
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Interaction of Amphotericin B with cholesteryl palmityl carbonate ester by Chuealee, Rabkwan, Wiedmann, Timothy S, Suedee, Roongnapa, Srichana, Teerapol

“…A cholesteryl carbonate ester was prepared and evaluated as a possible thermotropic liquid crystal excipient for dry powder inhalers. Cholesteryl palmityl…”
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Thermotropic behavior of sodium cholesteryl carbonate by Chuealee, Rabkwan, Wiedmann, Timothy S., Srichana, Teerapol

“…Sodium cholesteryl carbonate ester (SCC) was synthesized, and its phase behavior was studied. The chemical structure was assessed by solid-state infrared…”
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Formation of cholesterol crystals at a mucin coated substrate by XIANGMIN LIAO, WIEDMANN, Timothy S

“…High-resolution, tapping-mode atomic force microscopy (AFM) was used to monitor the early stage of the formation of cholesterol crystals under simulated…”
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