Search Results - "Wiedlocha, A."

RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789 by Nadratowska-Wesolowska, B, Haugsten, E M, Zakrzewska, M, Jakimowicz, P, Zhen, Y, Pajdzik, D, Wesche, J, Wiedlocha, A

“…FGFR1 (fibroblast growth factor receptor 1) regulates many key cellular responses including proliferation, migration and differentiation through activation of…”
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Design of fully active FGF-1 variants with increased stability by Zakrzewska, Malgorzata, Krowarsch, Daniel, Wiedlocha, Antoni, Otlewski, Jacek

“…Fibroblast growth factor 1 is a powerful mitogen playing an important role in morphogenesis, angiogenesis and wound healing and is therefore of potential…”
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Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1 2 activity via p38 MAPK by ZHEN, Y, SORENSEN, V, JIN, Y, SUO, Z, WIEDLOCHA, A

“…Indirubin-3'-monoxime is a derivative of the bis-indole alkaloid indirubin, an active ingredient of a traditional Chinese medical preparation that exhibits…”
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Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization by Wiedłocha, Antoni, Falnes, Pål Ø., Rapak, Andrzej, Muñoz, Raquel, Klingenberg, Olav, Olsnes, Sjur

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Signaling, internalization, and intracellular activity of fibroblast growth factor by Wiedłocha, A, Sørensen, V

“…The fibroblast growth factor (FGF) family contains 23 members in mammals including its prototype members FGF-1 and FGF-2. FGFs have been implicated in…”
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Expression of Human Protein Tyrosine Phosphatase Epsilon in Leucocytes: a Potential ERK Pathway‐Regulating Phosphatase by WABAKKEN, T., HAUGE, H., FINNE, E. F., WIEDLOCHA, A., AASHEIM, H.‐C.

“…The expression of protein tyrosine phosphatase epsilon (PTPε) was studied in human tissues and blood cells. High mRNA expression was observed in peripheral…”
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Translocation to Cytosol of Exogenous, CAAX-tagged Acidic Fibroblast Growth Factor (∗) by Wiediłdocha, Antoni, Falnes, Pål Ø., Rapak, Andrzej, Klingenberg, Olav, Muñoz, Raquel, Olsnes, Sjur

“…Acidic fibroblast growth factor (aFGF) added externally to cells has been proposed to enter the nucleus and stimulate DNA synthesis, but it has remained…”
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Intermediates in translocation of diphtheria toxin across the plasma membrane by MADSHUS, I. H, WIEDLOCHA, A, SANDVIG, K

“…Active diphtheria toxin consists of two parts, fragments A and B. Fragment A has enzymatic activity and inhibits protein synthesis. Fragment B binds to…”
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Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector by Wiedlocha, A., Madshus, I.H., Mach, H., Middaugh, C.R., Olsnes, S.

“…A fusion protein of acidic fibroblast growth factor and diphtheria toxin A‐fragment was disulfide‐linked to the toxin B‐fragment. The complex bound…”
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Functional diversity of FGF-2 isoforms by intracellular sorting by Sørensen, Vigdis, Nilsen, Trine, Wiȩdłocha, Antoni

“…Regulation of the subcellular localization of certain proteins is a mechanism for the regulation of their biological activities. FGF‐2 can be produced as…”
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Two Forms of the Heparin-binding EGF-like Growth Factor Precursor, a Receptor for Diphtheria Toxin by Loukianov, E V, Wiedlocha, A, Olsnes, S, Kozlov, Yu V

“…A new mRNA coding for the heparin-binding EGF-like growth factor (HB-EGF) was found in Vero cells. The corresponding cDNA had C-156 in place of T, which…”
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FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation by Szlachcic, Anna, Pala, Katarzyna, Zakrzewska, Malgorzata, Jakimowicz, Piotr, Wiedlocha, Antoni, Otlewski, Jacek

“…Fibroblast growth factor receptors (FGFRs) are overexpressed in a wide variety of tumors, such as breast, bladder, and prostate cancer, and therefore they are…”
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Transport of Exogenous Growth Factors and Cytokines to the Cytosol and to the Nucleus by Olsnes, Sjur, Klingenberg, Olav, Wiedlocha, Antoni

“…Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, Oslo, Norway Olsnes, Sjur, Olav Klingenberg, and Antoni Wi d ocha. Transport of…”
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Dual mode of signal transduction by externally added acidic fibroblast growth factor by Wiedłocha, A, Falnes, P O, Madshus, I H, Sandvig, K, Olsnes, S

“…Acidic fibroblast growth factor (aFGF), fused to diphtheria toxin and translocated into cells, stimulated DNA synthesis in toxin-resistant cells lacking…”
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The activity of two immunotoxins composed of monoclonal antibody MoAb-16 and A-chain of ricin (MoAb-16-RTA) or A-chain of mistletoe lectin I (MoAb-16-MLIA) by Paprocka, M, Wiedłocha, A, Walzel, H, Radzikowski, C

“…The A-chains of ricin obtained from Ricinus communis or mistletoe lectin I from Viscum album were coupled to the monoclonal, anti-L1210V antibody MoAb-16,…”
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Highly Stable Mutants of Human Fibroblast Growth Factor-1 Exhibit Prolonged Biological Action by Zakrzewska, Malgorzata, Krowarsch, Daniel, Wiedlocha, Antoni, Olsnes, Sjur, Otlewski, Jacek

“…Fibroblast growth factor 1 (FGF-1) shows strong angiogenic, osteogenic and tissue-injury repair properties that might be relevant to medical applications…”
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Immunomagnetic removal of L1210V leukemic cells from mouse bone marrow ex vivo by Wiedłocha, A, Paprocka, M, Radzikowski, C

“…The purging of mouse bone marrow from L1210V leukemic cells was attained ex vivo by using monoclonal IgM antibody against leukemic cells and magnetic particles…”
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Evading Apoptosis by Calcitriol-Differentiated Human Leukemic HL-60 Cells Is Not Mediated by Changes in CD95 Receptor System but by Increased Sensitivity of These Cells to Insulin by Marcinkowska, Ewa, Chrobak, Agnieszka, Więedłocha, Antoni

“…Previous studies revealed that 1,25-dihydroxyvitamin D3 (calcitriol)-induced differentiation of human promyelocytic leukemia cells leads to an increased…”
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Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain by Citores, L, Khnykin, D, Sørensen, V, Wesche, J, Klingenberg, O, Wiedłocha, A, Olsnes, S

“…Endocytic uptake and intracellular transport of acidic fibroblast growth factor (aFGF) was studied in cells transfected with FGF receptor 4 with mutations in…”
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Externally Added aFGF Mutants Do Not Require Extensive Unfolding for Transport to the Cytosol and the Nucleus in NIH/3T3 Cells by Wesche, Jørgen, Wiȩdłocha, Antoni, Falnes, Pål Ø, Choe, Senyon, Olsnes, Sjur

“…Acidic fibroblast growth factor (aFGF) is transported to the cytosol and the nucleus when added to cells expressing FGF receptors, implying that aFGF must…”
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