Search Results - "Wieckowska‐Gacek, Angelika"
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Western Diet Induces Impairment of Liver-Brain Axis Accelerating Neuroinflammation and Amyloid Pathology in Alzheimer's Disease
Published in Frontiers in aging neuroscience (01-04-2021)“…Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder and the most common cause of dementia. The prevailing AD hypothesis…”
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Induction of Brain Insulin Resistance and Alzheimer's Molecular Changes by Western Diet
Published in International journal of molecular sciences (25-04-2022)“…The term Western diet (WD) describes the consumption of large amounts of highly processed foods, rich in simple sugars and saturated fats. Long-term WD feeding…”
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Western diet as a trigger of Alzheimer’s disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
Published in Ageing research reviews (01-09-2021)“…[Display omitted] •Western diet (WD) can accelerate and enhance inflammaging and induction of Alzheimer’s disease (AD).•WD-induced obesity, metabolic disorders…”
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Brain insulin resistance and Alzheimer’s molecular changes induced by Western diet
Published in Alzheimer's & dementia (01-06-2023)“…Background Western diet (WD) is a type of nourishment based on ultra‐processed foods, rich in simple sugars and saturated fats. Long‐term consumption of WD may…”
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Systemic inflammation induced by LPS promotes insulin signaling disruption leading to Alzheimer‐like changes in wild type mice
Published in Alzheimer's & dementia (01-12-2023)“…Background One of the hypotheses for the ethiology of sporadic Alzheimer’s disease (AD) focuses on systemic inflammation as a driving force of aging. Another…”
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Greater sensitivity of the hippocampus than the entorhinal cortex in response to western diet, manifested by accelerated neuroinflammation and neurodegeneration in the progression of Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2023)“…Background The western diet (WD), characterized by a combination of simple carbohydrates, saturated fatty acids and cholesterol, is known to induce metabolic…”
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WESTERN DIET – FROM MICROGLIA DYSFUNCTION TO THE ACCELERATION OF ALZHEIMER'S DISEASE PATHOLOGY
Published in Acta neurobiologiae experimentalis (01-01-2022)“…Microglial phagocytosis in the early stage of Alzheimer's disease (AD) plays a beneficial role, however, during disease progression, seems to become…”
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WESTERN DIET AS A TRIGGER OF ALZHEIMER'S DISEASE: FROM METABOLIC SYNDROME TO NEURODEGENERATION
Published in Acta neurobiologiae experimentalis (01-01-2022)“…An excess of saturated fatty acids and simple sugars in the diet is a known environmental risk factor of Alzheimer's disease (AD) but the holistic view of the…”
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WESTERN DIET LEADS TO INSULIN RESISTANCE IN THE BRAIN AND MAY TRIGGER THE DEVELOPMENT OF ALZHEIMER'S DISEASE
Published in Acta neurobiologiae experimentalis (01-01-2022)“…Western diet (WD) is a type of nourishment based on ultra-processed foods. Long-term consumption of WD leads to disruption of insulin signaling and the…”
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