Search Results - "Wie, Myung Bok"

Benefits of hesperidin in central nervous system disorders: a review by Kim, Jeongtae, Wie, Myung-Bok, Ahn, Meejung, Tanaka, Akane, Matsuda, Hiroshi, Shin, Taekyun

“…Citrus species contain significant amounts of flavonoids that possess antioxidant activities; furthermore, dietary citrus is not associated with adverse…”
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Ulmus davidiana 60% edible ethanolic extract for prevention of pericyte apoptosis in diabetic retinopathy by Kim, Iljin, Seo, Jieun, Lee, Dong Hyun, Kim, Yo-Han, Kim, Jun-Hyung, Wie, Myung-Bok, Byun, Jun-Kyu, Yun, Jang-Hyuk

“…Diabetic retinopathy (DR) is a disease that causes visual deficiency owing to vascular leakage or abnormal angiogenesis. Pericyte apoptosis is considered one…”
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A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis by Park, Jeongho, Kim, Hyun-Ouk, Park, Kwang-Hyun, Wie, Myung-Bok, Choi, Sun-Eun, Yun, Jang-Hyuk

“…As abnormal angiogenesis is associated with exacerbation of various diseases, precise control over angiogenesis is imperative. Vascular endothelial growth…”
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Zinc Oxide Nanoparticles Induce Autophagy and Apoptosis via Oxidative Injury and Pro-Inflammatory Cytokines in Primary Astrocyte Cultures by Song, Woo-Ju, Jeong, Myung-Seon, Choi, Dong-Min, Kim, Kil-Nam, Wie, Myung-Bok

“…The present study examined the potential toxic concentrations of zinc oxide nanoparticles (ZnO NPs) and associated autophagy and apoptosis-related injuries in…”
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Zinc Oxide Nanoparticles Exhibit Both Cyclooxygenase- and Lipoxygenase-Mediated Apoptosis in Human Bone Marrow-Derived Mesenchymal Stem Cells by Kim, Dong-Yung, Kim, Jun-Hyung, Lee, Jae-Chul, Won, Moo-Ho, Yang, Se-Ran, Kim, Hyoung-Chun, Wie, Myung-Bok

“…Nanoparticles (NPs) have been recognized as both useful tools and potentially toxic materials in various industrial and medicinal fields. Previously, we found…”
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Esculetin and Fucoidan Attenuate Autophagy and Apoptosis Induced by Zinc Oxide Nanoparticles through Modulating Reactive Astrocyte and Proinflammatory Cytokines in the Rat Brain by Song, Woo-Ju, Kim, Jeongtae, Shin, Taekyun, Jeong, Myeong-Seon, Kim, Kil-Nam, Yun, Jang-Hyuk, Wie, Myung-Bok

“…We examined the protective effects of esculetin and fucoidan against the neurotoxicity of ZnO NPs in rats. Ninety rats were divided into nine groups and…”
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Inhibitors of Lipoxygenase and Cyclooxygenase-2 Attenuate Trimethyltin-Induced Neurotoxicity through Regulating Oxidative Stress and Pro-Inflammatory Cytokines in Human Neuroblastoma SH-SY5Y Cells by Song, Woo-Ju, Yun, Jang-Hyuk, Jeong, Myeong-Seon, Kim, Kil-Nam, Shin, Taekyun, Kim, Hyoung-Chun, Wie, Myung-Bok

“…Trimethyltin (TMT) is an environmental neurotoxin that mediates dopaminergic neuronal injury in the brain. In this study, we characterized the toxic mechanism…”
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Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats by Shin, Eun-Joo, Ko, Kwang Ho, Kim, Won-Ki, Chae, Jong Seok, Yen, Tran Phi Hoang, Kim, Hyun Ji, Wie, Myung-Bok, Kim, Hyoung-Chun

“…Oxidative stress may contribute to epileptogenicity in genetic models of epilepsy. To address this, we examined the enzymatic activity of cytosolic Cu/Zn…”
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Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysaccharide administration by Jung, Bae Dong, Shin, Eun-Joo, Nguyen, Xuan-Khanh Thi, Jin, Chun-Hui, Bach, Jae-Hyung, Park, Seok Joo, Nah, Seung-Yeol, Wie, Myung-Bok, Bing, Guoying, Kim, Hyoung-Chun

“…Accumulated evidence has indicated that neuroinflammation is one of the important etiologic factors of Parkinson's disease (PD). Earlier studies have employed…”
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Protection against kainate neurotoxicity by ginsenosides: Attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress by Shin, Eun-Joo, Jeong, Ji Hoon, Kim, A-Young, Koh, Young Ho, Nah, Seung-Yeoul, Kim, Won-Ki, Ko, Kwang Ho, Kim, Hyun Ji, Wie, Myung-Bok, Kwon, Yong Soo, Yoneda, Yukio, Kim, Hyoung-Chun

“…We previously demonstrated that kainic acid (KA)‐mediated mitochondrial oxidative stress contributed to hippocampal degeneration and that ginsenosides…”
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3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro by Zhang, Wei, Shin, Eun-Joo, Wang, Tongguang, Lee, Phil Ho, Pang, Hao, Wie, Myung-Bok, Kim, Won-Ki, Kim, Seong-Jin, Huang, Wen-Hsin, Wang, Yongjun, Zhang, Wanqin, Hong, Jau-Shyong, Kim, Hyoung-Chun

“…We investigated the neuroprotective property of analogs of dextromethorphan (DM) in lipopolysaccharide (LPS) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine…”
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High-dose dextromethorphan produces myelinoid bodies in the hippocampus of rats by Tran, Hai-Quyen, Chung, Yoon Hee, Shin, Eun-Joo, Kim, Won Ki, Lee, Jae-Chul, Jeong, Ji Hoon, Wie, Myung Bok, Jang, Choon-Gon, Yamada, Kiyofumi, Nabeshima, Toshitaka, Kim, Hyoung-Chun

“…Dextromethorphan (DM) administered at supra-antitussive doses produce psychotoxic and neurotoxic effects in humans. We administered DM (80 mg/kg) to rats…”
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Kainate-induced mitochondrial oxidative stress contributes to hippocampal degeneration in senescence-accelerated mice by Shin, Eun-Joo, Jeong, Ji Hoon, Bing, Guoying, Park, Eon Sub, Chae, Jong Seok, Yen, Tran Phi Hoang, Kim, Won-Ki, Wie, Myung-Bok, Jung, Bae-Dong, Kim, Hyun Ji, Lee, Sung-Youl, Kim, Hyoung-Chun

“…We have demonstrated that kainate (KA) induces a reduction in mitochondrial Mn-superoxide dismutase (Mn-SOD) expression in the rat hippocampus and that…”
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Zinc oxide nanoparticles induce lipoxygenase-mediated apoptosis and necrosis in human neuroblastoma SH-SY5Y cells by Kim, Jun-Hyung, Jeong, Myeong Seon, Kim, Dong-Yung, Her, Song, Wie, Myung-Bok

“…Zinc oxide nanoparticles (ZnO NPs) are known to induce oxidative stress and modulate an inflammatory process in various cell types. Although the cytotoxic…”
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Phenidone protects the nigral dopaminergic neurons from LPS-induced neurotoxicity by Li, Zhengyi, Choi, Dong-Young, Shin, Eun-Joo, Hunter, Randy L., Jin, Chun Hui, Wie, Myung-Bok, Kim, Min Soo, Park, Seok Joo, Bing, Guoying, Kim, Hyoung-Chun

“…Anti-inflammatory drugs such as ibuprofen appear to prevent the development of Parkinson's disease (PD); however, long-term use has undesirable side-effects. A…”
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Zinc Oxide Nanoparticles Exhibit Both Cyclooxygenase- and Lipoxygenase-Mediated Apoptosis in Human Bone Marrow-Derived Mesenchymal Stem Cells by Kim, Dong-Yung, Kim, Jun-Hyung, Lee, Jae-Chul, Won, Moo-Ho, Yang, Se-Ran, Kim, Hyoung-Chun, Wie, Myung-Bok

“…Nanoparticles (NPs) have been recognized as both useful tools and potentially toxic materials in various industrial and medicinal fields. Previously, we found…”
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Ginsenoside Re Rescues Methamphetamine-Induced Oxidative Damage, Mitochondrial Dysfunction, Microglial Activation, and Dopaminergic Degeneration by Inhibiting the Protein Kinase Cδ Gene by Shin, Eun-Joo, Shin, Seung Woo, Nguyen, Thuy-Ty Lan, Park, Dae Hun, Wie, Myung-Bok, Jang, Choon-Gon, Nah, Seung-Yeol, Yang, Byung Wook, Ko, Sung Kwon, Nabeshima, Toshitaka, Kim, Hyoung-Chun

“…Ginsenoside Re, one of the main constituents of Panax ginseng , possesses novel antioxidant and anti-inflammatory properties. However, the pharmacological…”
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Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism by Shin, Eun-Joo, Nam, Yunsung, Tu, Thu-Hien Thi, Lim, Yong Kwang, Wie, Myung-Bok, Kim, Dae-Joong, Jeong, Ji Hoon, Kim, Hyoung-Chun

“…We investigated whether protein kinase C (PKC) is involved in trimethyltin (TMT)-induced neurotoxicity. TMT treatment (2.8 mg/kg, i.p.) significantly increased…”
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Melatonin Attenuates Memory Impairment Induced by Klotho Gene Deficiency Via Interactive Signaling Between MT2 Receptor, ERK, and Nrf2-Related Antioxidant Potential by Shin, Eun-Joo, Chung, Yoon Hee, Le, Hoang-Lan Thi, Jeong, Ji Hoon, Dang, Duy-Khanh, Nam, Yunsung, Wie, Myung Bok, Nah, Seung-Yeol, Nabeshima, Yo-Ichi, Nabeshima, Toshitaka, Kim, Hyoung-Chun

“…Background: We demonstrated that oxidative stress plays a crucial role in cognitive impairment in klotho mutant mice, a genetic model of aging. Since…”
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Quercetin Attenuates Oxygen–Glucose Deprivation- and Excitotoxin-Induced Neurotoxicity in Primary Cortical Cell Cultures by Ha, Hyun Joo, Kwon, Yong Soo, Park, Shin Mi, Shin, Taekyun, Park, Jun Hong, Kim, Hyoung Chun, Kwon, Myung Sang, Wie, Myung Bok

“…The possible role of quercetin, a naturally occurring plant flavonoid, in protecting against oxygen–glucose deprivation (OGD)-, excitotoxins-, and free…”
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