Search Results - "Widom, Russell L."

Cartilage oligomeric matrix protein is overexpressed by scleroderma dermal fibroblasts by Farina, Giuseppina, Lemaire, Raphael, Korn, Joseph H., Widom, Russell L.

“…Cartilage oligomeric matrix protein (COMP) is an extracellular glycoprotein that belongs to the thrombospondin gene family. It is found predominantly in…”
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Differential Responses of Bacillus subtilis rRNA Promoters to Nutritional Stress by SAMARRAI, Walied, LIU, David X, WHITE, Ann-Marie, STUDAMIRE, Barbara, EDELSTEIN, Jacob, SRIVASTAVA, Anita, WIDOM, Russell L, RUDNER, Rivka

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Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-β peptide by Yamin, Rina, Bagchi, Sandipan, Hildebrant, Rick, Scaloni, Andrea, Widom, Russell L, Abraham, Carmela R

“…Considerable evidence indicates that the amyloid-β (Aβ) peptide, a proteolytic fragment of the amyloid precursor protein, is the pathogenic agent in…”
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Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad‐independent TGF‐β pathway – implication of C‐Krox and Sp1 by Renard, Emmanuelle, Chadjichristos, Christos, Kypriotou, Magdalini, Beauchef, Gallic, Bordat, Pascal, Dompmartin, Anne, Widom, Russell L., Boumediene, Karim, Pujol, Jean‐Pierre, Galéra, Philippe

“…Despite several investigations, the transcriptional mechanisms which regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either…”
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c-Krox down-regulates the expression of UDP–glucose dehydrogenase in chondrocytes by Beauchef, Gallic, Kypriotou, Magdalini, Chadjichristos, Christos, Widom, Russell L., Porée, Benoît, Renard, Emmanuelle, Moslemi, Safa, Wegrowski, Yanusz, Maquart, François-Xavier, Pujol, Jean-Pierre, Galéra, Philippe

“…Chondrocyte glycosaminoglycan (GAG) synthesis is regulated by the availability of UDP–glucuronate, the substrate of glucuronosyl transferases which form the…”
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Regulation of matrix biosynthesis and degradation in systemic sclerosis by Widom, Russell L

“…The regulation of matrix biosynthesis in systemic sclerosis has been the focus of many studies, because excessive matrix synthesis causes pathologic changes,…”
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The hcKrox gene family regulates multiple extracellular matrix genes by Widom, Russell L., Lee, John Y., Joseph, Cuthbert, Gordon-Froome, Ingrid, Korn, Joseph H.

“…The transcription factor cKrox was originally identified as a protein that bound to a negative transcription regulatory element in the murine α1(I) collagen…”
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Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression by Widom, Russell L., Culic, Ivana, Lee, John Y., Korn, Joseph H.

“…cKrox is a novel zinc finger-containing transcription factor that binds to the α1(I) and α2(I) collagen gene promoters. The gene coding for cKrox is a new…”
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Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-[beta] peptide by Yamin, Rina, Bagchi, Sandipan, Hildebrant, Rick, Scaloni, Andrea, Widom, Russell L, Abraham, Carmela R

“…Considerable evidence indicates that the amyloid-[beta] (A[beta]) peptide, a proteolytic fragment of the amyloid precursor protein, is the pathogenic agent in…”
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Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-[beta] pathway - implication of C-Krox and Sp1 by Renard, Emmanuelle, Chadjichristos, Christos, Kypriotou, Magdalini, Beauchef, Gallic, Bordat, Pascal, Dompmartin, Anne, Widom, Russell L, Boumediene, Karim, Pujol, Jean-Pierre, Galéra, Philippe

“…Despite several investigations, the transcriptional mechanisms which regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either…”
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Repression by ARP-1 sensitizes apolipoprotein AI gene responsiveness to RXR alpha and retinoic acid by WIDOM, R. L, RHEE, M, KARATHANASIS, S. K

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Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells by WIDON, R. L, LADIAS, J. A. A, KOUIDOU, S, KARATHANASIS, S. K

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Functional Characterization of the Human Biglycan 5′‐Flanking DNA and Binding of the Transcription Factor c‐Krox by Heegaard, Anne‐Marie, Robey, Pamela Gehron, Vogel, Walther, Just, Walter, Widom, Russell L., Schøller, Jørgen, Fisher, Larry W., Young, Marian F.

“…The transcriptional regulation of human biglycan expression under normal and pathological conditions was studied. The 5′‐flanking regions of the human and…”
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Repression by ARP-1 Sensitizes Apolipoprotein A1 Gene Responsiveness to RXRα and Retinoic Acid by Widom, Russell L., Rhee, Myungchull, Karathanasis, Sotirios K.

“…The gene coding for apolipoprotein AI (apoAI), a lipid binding protein involved in the transport of cholesterol and other lipids in the plasma, is expressed in…”
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NOTES: A Retinoic Acid-Responsive Element in the Apolipoprotein AI Gene Distinguishes between Two Different Retinoic Acid Response Pathways by Rottman, Jeffrey N., Widom, Russell L., Nadal-Ginard, Bernardo, Mahdavi, Vijak, Karathanasis, Sotirios K.

“…The gene coding for apolipoprotein AI, a plasma protein involved in the transport of cholesterol and other lipids in the plasma, is expressed predominantly in…”
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Synergistic Interactions between Transcription Factors Control Expression of the Apolipoprotein AI Gene in Liver Cells by Widom, Russell L., Ladias, John A. A., Kouidou, Sophia, Karathanasis, Sotirios K.

“…The gene coding for apolipoprotein AI (apoAI), a plasma protein involved in the transport of cholesterol and other lipids in the plasma, is expressed…”
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