Search Results - "Widmer, Lukas A"

The motor domain of the kinesin Kip2 promotes microtubule polymerization at microtubule tips by Chen, Xiuzhen, Portran, Didier, Widmer, Lukas A, Stangier, Marcel M, Czub, Mateusz P, Liakopoulos, Dimitris, Stelling, Jörg, Steinmetz, Michel O, Barral, Yves

“…Kinesins are microtubule-dependent motor proteins, some of which moonlight as microtubule polymerases, such as the yeast protein Kip2. Here, we show that the…”
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Rethinking clinical study data: why we should respect analysis results as data by Barros, Joana M., Widmer, Lukas A., Baillie, Mark, Wandel, Simon

“…The development and approval of new treatments generates large volumes of results, such as summaries of efficacy and safety. However, it is commonly overlooked…”
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Remote control of microtubule plus-end dynamics and function from the minus-end by Chen, Xiuzhen, Widmer, Lukas A, Stangier, Marcel M, Steinmetz, Michel O, Stelling, Jörg, Barral, Yves

“…In eukaryotes, the organization and function of the microtubule cytoskeleton depend on the allocation of different roles to individual microtubules. For…”
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Effect of Immunosuppression on T-Helper 2 and B-Cell Responses to Influenza Vaccination by Egli, Adrian, Humar, Atul, Widmer, Lukas A., Lisboa, Luiz F., Santer, Deanna M., Mueller, Thomas, Stelling, Joerg, Baluch, Aliyah, O'Shea, Daire, Houghton, Michael, Kumar, Deepali

“…Background. Influenza vaccine immunogenicity is suboptimal in immunocompromised patients. However, there are limited data on the interplay of T- and B-cell…”
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Changing Face of Vaccination in Immunocompromised Hosts by O’Shea, Daire, Widmer, Lukas A., Stelling, Jörg, Egli, Adrian

“…Infection prevention is a key component of care and an important determinant of clinical outcomes in a diverse population of immunocompromised hosts…”
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Mapping complex spatio-temporal models to image space: The virtual microscope by Samuylov, Denis K., Widmer, Lukas A., Szekely, Gabor, Paul, Gregory

“…Simulating synthetic image data is crucial for the design and validation of bio-imaging pipelines. Most of the existing frameworks assume objects in pixel…”
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A Coupled Stochastic Model Explains Differences in Cry Knockout Behavior by Abel, John H., Widmer, Lukas A., John, Peter C. St, Stelling, Jorg, Doyle, Francis J.

“…In the mammalian suprachiasmatic nucleus (SCN), a population of noisy cell-autonomous oscillators synchronizes to generate robust circadian rhythms at the…”
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Principled Drug-Drug Interaction Terms for Bayesian Logistic Regression Models of Drug Safety in Oncology Phase I Combination Trials by Widmer, Lukas A, Bean, Andrew, Ohlssen, David, Weber, Sebastian

“…In Oncology, trials evaluating drug combinations are becoming more common. While combination therapies bring the potential for greater efficacy, they also…”
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Why we should respect analysis results as data by Barros, Joana M, Widmer, Lukas A, Baillie, Mark, Wandel, Simon

“…The development and approval of new treatments generates large volumes of results, such as summaries of efficacy and safety. However, it is commonly overlooked…”
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A Coupled Stochastic Model Explains Differences in Circadian Behavior of Cry1 and Cry2 Knockouts by Abel, John H, Widmer, Lukas A, John, Peter C. St, Stelling, Jörg, DoyleIII, Francis J

“…In the mammalian suprachiasmatic nucleus (SCN), a population of noisy cell-autonomous oscillators synchronizes to generate robust circadian rhythms at the…”
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