Search Results - "Widmer, Lukas"

The motor domain of the kinesin Kip2 promotes microtubule polymerization at microtubule tips by Chen, Xiuzhen, Portran, Didier, Widmer, Lukas A, Stangier, Marcel M, Czub, Mateusz P, Liakopoulos, Dimitris, Stelling, Jörg, Steinmetz, Michel O, Barral, Yves

“…Kinesins are microtubule-dependent motor proteins, some of which moonlight as microtubule polymerases, such as the yeast protein Kip2. Here, we show that the…”
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Rethinking clinical study data: why we should respect analysis results as data by Barros, Joana M., Widmer, Lukas A., Baillie, Mark, Wandel, Simon

“…The development and approval of new treatments generates large volumes of results, such as summaries of efficacy and safety. However, it is commonly overlooked…”
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More Than Talking About the Weekend: Content of Case-Irrelevant Communication Within the OR Team by Widmer, Lukas W., Keller, Sandra, Tschan, Franziska, Semmer, Norbert K., Holzer, Eliane, Candinas, Daniel, Beldi, Guido

“…Background Case-irrelevant communication (CIC) is defined as “any conversation” irrelevant to the case. It includes small talk, but also communication related…”
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Where Am I? Niche constraints due to morphological specialization in two Tanganyikan cichlid fish species by Widmer, Lukas, Indermaur, Adrian, Egger, Bernd, Salzburger, Walter

“…Food resource specialization within novel environments is considered a common axis of diversification in adaptive radiations. Feeding specializations are often…”
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Remote control of microtubule plus-end dynamics and function from the minus-end by Chen, Xiuzhen, Widmer, Lukas A, Stangier, Marcel M, Steinmetz, Michel O, Stelling, Jörg, Barral, Yves

“…In eukaryotes, the organization and function of the microtubule cytoskeleton depend on the allocation of different roles to individual microtubules. For…”
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Docetaxel, Cisplatin, and Fluorouracil; Docetaxel and Cisplatin; and Epirubicin, Cisplatin, and Fluorouracil As Systemic Treatment for Advanced Gastric Carcinoma: A Randomized Phase II Trial of the Swiss Group for Clinical Cancer Research by ROTH, Arnaud D, FAZIO, Nicola, WERNLI, Martin, LESLIE, Martin, GLYNNE-JONES, Robert, WIDMER, Lukas, SEYMOUR, Matthew, DE BRAUD, Filippo, STUPP, Roger, FALK, Stephen, BERNHARD, Jürg, SALETTI, Piercarlo, KÖBERLE, Dieter, BORNER, Markus M, RUFIBACH, Kaspar, MAIBACH, Rudolf

“…This randomized phase II trial evaluated two docetaxel-based regimens to see which would be most promising according to overall response rate (ORR) for…”
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Gene expression dynamics during rapid organismal diversification in African cichlid fishes by El Taher, Athimed, Böhne, Astrid, Boileau, Nicolas, Ronco, Fabrizia, Indermaur, Adrian, Widmer, Lukas, Salzburger, Walter

“…Changes in gene expression play a fundamental role in phenotypic evolution. Transcriptome evolutionary dynamics have so far mainly been compared among…”
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Effect of Immunosuppression on T-Helper 2 and B-Cell Responses to Influenza Vaccination by Egli, Adrian, Humar, Atul, Widmer, Lukas A., Lisboa, Luiz F., Santer, Deanna M., Mueller, Thomas, Stelling, Joerg, Baluch, Aliyah, O'Shea, Daire, Houghton, Michael, Kumar, Deepali

“…Background. Influenza vaccine immunogenicity is suboptimal in immunocompromised patients. However, there are limited data on the interplay of T- and B-cell…”
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Mortality, risk factors and causes of death in Swedish patients with open tibial fractures - a nationwide study of 3, 777 patients by Tampe, Ulrika, Widmer, Lukas W, Weiss, Rüdiger J, Jansson, Karl-Åke

“…Open tibial fractures are serious, complicated injuries. Previous studies suggested an increased risk of death, however, this has not been studied in large…”
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Reliability and Repeatability of Toe Pressures Measured With Laser Doppler and Portable and Stationary Photoplethysmography Devices by Widmer, Lukas W, Vikatmaa, Pirkka, Aho, Pekka, Lepäntalo, Mauri, Venermo, Maarit

“…Background There are two principally different methods for measuring toe pressures (TP)—photoplethysmography (PPG) and laser Doppler (LD). PPG is based on…”
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Cost-effectiveness analysis of malaria chemoprophylaxis for travellers to West-Africa by Widmer, Lukas L, Blank, Patricia R, Van Herck, Koen, Hatz, Christoph, Schlagenhauf, Patricia

“…The importation of malaria to non-endemic countries remains a major cause of travel-related morbidity and a leading cause of travel-related hospitalizations…”
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Changing Face of Vaccination in Immunocompromised Hosts by O’Shea, Daire, Widmer, Lukas A., Stelling, Jörg, Egli, Adrian

“…Infection prevention is a key component of care and an important determinant of clinical outcomes in a diverse population of immunocompromised hosts…”
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Sequence-based prediction of permissive stretches for internal protein tagging and knockdown by Oesterle, Sabine, Roberts, Tania Michelle, Widmer, Lukas Andreas, Mustafa, Harun, Panke, Sven, Billerbeck, Sonja

“…Internal tagging of proteins by inserting small functional peptides into surface accessible permissive sites has proven to be an indispensable tool for basic…”
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Mapping complex spatio-temporal models to image space: The virtual microscope by Samuylov, Denis K., Widmer, Lukas A., Szekely, Gabor, Paul, Gregory

“…Simulating synthetic image data is crucial for the design and validation of bio-imaging pipelines. Most of the existing frameworks assume objects in pixel…”
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Simulation in vascular access surgery by Widmer, Matthias K, Davidson, Ingemar, Widmer, Lukas W, Schmidli, Jürg, Wyss, Thomas R

“…In the last years, simulation training has become widespread in different areas of medicine due to social expectations, political accountability and…”
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Bridging intracellular scales by mechanistic computational models by Widmer, Lukas Andreas, Stelling, Jörg

“…[Display omitted] •Intracellular dynamics span many spatial, temporal, and molecular abundance scales.•Multi-class models enable to bridge scales while being…”
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Point‐Combination Transect (PCT): Incorporation of small underwater cameras to study fish communities by Widmer, Lukas, Heule, Elia, Colombo, Marco, Rueegg, Attila, Indermaur, Adrian, Ronco, Fabrizia, Salzburger, Walter, Sutherland, Chris

“…Available underwater visual census (UVC) methods such as line transects or point count observations are widely used to obtain community data of underwater…”
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Poster: AML-142 Patients at High Risk of Relapse Post-Transplant: A Phase 1 Study Design With a Novel Treatment Strategy Using the Estimand Framework by Al-Atrash, Gheath, Craddock, Charles, Schmid, Christoph, Xu, Yunnan, Weber, Hans-Jochen, Eldjerou, Lamis, Weber, Sebastian, Widmer, Lukas, Zeiser, Robert

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Clipping of a superior hypophyseal artery aneurysm during endoscopic transnasal removal of a Rathke cleft cyst: a case report by Serra, Carlo, Sebök, Martina, Widmer, Lukas, Neidert, Marian Christoph, Regli, Luca

“…The concomitant presence of an aneurysm in contact with a sellar lesion usually contraindicates a transsphenoidal approach (TSS). Clipping of an intracranial…”
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Fast treatment of anterior shoulder dislocations with two sedation-free methods: The Davos self-reduction method and Arlt method by Widmer, Lukas Werner, Lerch, Till Dominic, Genthner, Anna, Pozzi, Lara, Geiger, James, Frei, Hans-Curd

“…Background Various reduction techniques exist to treat traumatic shoulder dislocation, but best management remains unclear. Aims To investigate the reduction…”
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