Search Results - "Widhopf II, G F"
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Cirmtuzumab inhibits Wnt5a-induced Rac1 activation in chronic lymphocytic leukemia treated with ibrutinib
Published in Leukemia (01-06-2017)“…Signaling via the B cell receptor (BCR) plays an important role in the pathogenesis and progression of chronic lymphocytic leukemia (CLL). This is underscored…”
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Wnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells
Published in Leukemia (01-12-2017)“…ROR1 (receptor tyrosine kinase-like orphan receptor 1) is a conserved, oncoembryonic surface antigen expressed in chronic lymphocytic leukemia (CLL). We found…”
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Abstract P2-01-10: Withdrawn
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract This abstract was withdrawn by the authors. Citation Format: Hasan MK, Widhopf II GF, Zhang S, Shen Z, Briggs SP, Kipps TJ. Withdrawn [abstract]. In:…”
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Normal B Cells Express 51p1-Encoded Ig Heavy Chains That Are Distinct From Those Expressed by Chronic Lymphocytic Leukemia B Cells
Published in The Journal of immunology (1950) (01-01-2001)“…51p1 is an allele of V(H)1-69 that frequently is expressed by chronic lymphocytic leukemia (CLL) B cells with little or no somatic mutation. The rearranged…”
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Transgenic Expression of a Human Polyreactive Ig Expressed in Chronic Lymphocytic Leukemia Generates Memory-Type B Cells That Respond to Nonspecific Immune Activation
Published in The Journal of immunology (1950) (15-02-2004)“…We generated transgenic mice, designated SMI, expressing unmutated H and L chain Ig genes encoding a low-affinity, polyreactive human (h)IgM/kappa rheumatoid…”
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