Search Results - "Widgren, Esther E."

Characterization of an Eppin Protein Complex from Human Semen and Spermatozoa by Wang, Zengjun, Widgren, Esther E, Richardson, Richard T, O'Rand, Michael G

“…Eppin (SPINLW1; serine peptidase inhibitor-like with Kunitz and WAP domains 1 (eppin); epididymal protease inhibitor) coats the surface of human ejaculate…”
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Inhibition of Human Sperm Motility by Contraceptive Anti-Eppin Antibodies from Infertile Male Monkeys: Effect on Cyclic Adenosine Monophosphate by O'Rand, Michael G, Widgren, Esther E, Beyler, Stan, Richardson, Richard T

“…Epididymal protease inhibitor (eppin [official symbol, SPINLW1]) is of interest as a male contraceptive target because of its specificity and location on the…”
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Nuclear Autoantigenic Sperm Protein (NASP), a Linker Histone Chaperone That Is Required for Cell Proliferation by Richardson, Richard T., Alekseev, Oleg M., Grossman, Gail, Widgren, Esther E., Thresher, Randy, Wagner, Eric J., Sullivan, Kelly D., Marzluff, William F., O'Rand, Michael G.

“…A multichaperone nucleosome-remodeling complex that contains the H1 linker histone chaperone nuclear autoantigenic sperm protein (NASP) has recently been…”
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Functional studies of eppin by O'Rand, Michael G, Widgren, Esther E, Hamil, Katherine G, Silva, Erick J, Richardson, Richard T

“…Our laboratory has characterized EPPIN [epididymal protease inhibitor; SPINLW1] as a novel gene on human chromosome 20q12-13.2, which encodes a cysteine-rich…”
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Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella by Lea, Isabel A, Widgren, Esther E, O'Rand, Michael G

“…Sperm protein 17 (Sp17) is a three-domain protein that contains: 1) a highly conserved N-terminal domain that is 45% identical to the human type II alpha…”
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Overexpression of the Linker Histone-binding Protein tNASP Affects Progression through the Cell Cycle by Alekseev, Oleg M, Bencic, David C, Richardson, Richard T, Widgren, Esther E, O'Rand, Michael G

“…NASP is an H1 histone-binding protein that is cell cycle-regulated and occurs in two major forms: tNASP, found in gametes, embryonic cells, and transformed…”
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Loss of Calcium in Human Spermatozoa via EPPIN, the Semenogelin Receptor by O'RAND, Michael G, WIDGREN, Esther E

“…The development of a new male contraceptive requires a transition from animal model to human and an understanding of the mechanisms involved in the target's…”
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Characterization of an Eppin Protein Complex from Human Semen and Spermatozoa1 by Wang, Zengjun, Widgren, Esther E, Richardson, Richard T, O'Rand, Michael G

“…Eppin (SPINLW1; serine peptidase inhibitor-like with Kunitz and WAP domains 1 (eppin); epididymal protease inhibitor) coats the surface of human ejaculate…”
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Loss of Calcium in Human Spermatozoa via EPPIN, the Semenogelin Receptor1 by O'Rand, Michael G, Widgren, Esther E

“…The development of a new male contraceptive requires a transition from animal model to human and an understanding of the mechanisms involved in the target's…”
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Association of NASP with HSP90 in mouse spermatogenic cells: stimulation of ATPase activity and transport of linker histones into nuclei by Alekseev, Oleg M, Widgren, Esther E, Richardson, Richard T, O'Rand, Michael G

“…NASP (nuclear autoantigenic sperm protein) is a linker histone-binding protein found in all dividing cells that is regulated by the cell cycle (Richardson, R…”
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Inhibition of Human Sperm Motility by Contraceptive Anti-Eppin Antibodies from Infertile Male Monkeys: Effect on Cyclic Adenosine Monophosphate1 by O'Rand, Michael G, Widgren, Esther E, Beyler, Stan, Richardson, Richard T

“…Epididymal protease inhibitor (eppin [official symbol, SPINLW1]) is of interest as a male contraceptive target because of its specificity and location on the…”
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Characterization of the Histone H1-binding Protein, NASP, as a Cell Cycle-regulated Somatic Protein by Richardson, Richard T., Batova, Iglika N., Widgren, Esther E., Zheng, Lian-Xing, Whitfield, Michael, Marzluff, William F., O'Rand, Michael G.

“…Nuclear autoantigenic sperm protein (NASP), initially described as a highly autoimmunogenic testis and sperm-specific protein, is a histone-binding protein…”
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Epididymal Protein Targets: A Brief History of the Development of Epididymal Protease Inhibitor as a Contraceptive by O'rand, Michael G., Widgren, Esther E., Hamil, Katherine G., Silva, Erick J., Richardson, Richard T.

“…The Laboratories for Reproductive Biology at the University of North Carolina at Chapel Hill began collaboration with Human Genome Sciences (Rockville,…”
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Association of NASP with HSP90 in Mouse Spermatogenic Cells by Alekseev, Oleg M., Widgren, Esther E., Richardson, Richard T., O'Rand, Michael G.

“…NASP (nuclear autoantigenic sperm protein) is a linker histone-binding protein found in all dividing cells that is regulated by the cell cycle (Richardson, R…”
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Analysis of recombinant mouse zona pellucida protein 2 (ZP2) constructs for immunocontraception by Lea, Isabel A., Widgren, Esther E., O’Rand, Michael G.

“…In this study we have examined the potential of recombinant mouse zona pellucida glycoprotein 2 (ZP2) as a target for immunocontraception. Immunogenicity…”
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Characterization of the rabbit sperm membrane autoantigen, RSA, as a lectin-like zona binding protein by O'Rand, Michael G., Widgren, Esther E., Fisher, Susan J.

“…Adhesion between spermatozoa and the egg's extracellular coat, the zona pellucida, involves the sperm's zona binding proteins (ZBP) and their interaction with…”
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Sequence and localization of human NASP: Conservation of a Xenopus histone-binding protein by O'Rand, Michael G., Richardson, Richard T., Zimmerman, Lisa J., Widgren, Esther E.

“…In this study the sequence and localization of human testicular NASP (nuclear autoantigenic sperm protein) are reported. NASP cDNA contains 2561 nt encoding a…”
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Characterization of Sp17: a ubiquitous three domain protein that binds heparin by Wen, Y, Richardson, R T, Widgren, E E, O'Rand, M G

“…Sp17 is a protein that was originally thought to be expressed exclusively in the testis and whose primary function was binding to the extracellular matrix of…”
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Characterization of Sp17: a ubiquitous three domain protein that binds heparin by WEN, Ying, RICHARDSON, Richard T., WIDGREN, Esther E., O'RAND, Michael G.

“…Sp17 is a protein that was originally thought to be expressed exclusively in the testis and whose primary function was binding to the extracellular matrix of…”
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Sequence and Localization of the Mouse Sperm Autoantigenic Protein, Sp171 by Kong, Min, Richardson, Richard T., Widgren, Esther E., O’Rand, Michael G.

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