Search Results - "Widgerow, Alan D"

Regeneration of fat cells from myofibroblasts during wound healing by Plikus, Maksim V., Guerrero-Juarez, Christian F., Ito, Mayumi, Li, Yun Rose, Dedhia, Priya H., Zheng, Ying, Shao, Mengle, Gay, Denise L., Ramos, Raul, Hsi, Tsai-Ching, Oh, Ji Won, Wang, Xiaojie, Ramirez, Amanda, Konopelski, Sara E., Elzein, Arijh, Wang, Anne, Supapannachart, Rarinthip June, Lee, Hye-Lim, Lim, Chae Ho, Nace, Arben, Guo, Amy, Treffeisen, Elsa, Andl, Thomas, Ramirez, Ricardo N., Murad, Rabi, Offermanns, Stefan, Metzger, Daniel, Chambon, Pierre, Widgerow, Alan D., Tuan, Tai-Lan, Mortazavi, Ali, Gupta, Rana K., Hamilton, Bruce A., Millar, Sarah E., Seale, Patrick, Pear, Warren S., Lazar, Mitchell A., Cotsarelis, George

“…Although regeneration through the reprogramming of one cell lineage to another occurs in fish and amphibians, it has not been observed in mammals. We…”
Get full text

Stromal vascular fraction: A regenerative reality? Part 1: Current concepts and review of the literature by Nguyen, Andrew, Guo, James, Banyard, Derek A, Fadavi, Darya, Toranto, Jason D, Wirth, Garrett A, Paydar, Keyianoosh Z, Evans, Gregory R.D, Widgerow, Alan D

“…Summary Stromal Vascular Fraction (SVF) is a heterogeneous collection of cells contained within adipose tissue that is traditionally isolated using enzymes…”
Get full text

Cellular/extracellular matrix cross-talk in scar evolution and control by Widgerow, Alan D.

“…ABSTRACT The principles of scar evolution and control are recognized and defined. Further clarity has been shed on these principles with the elucidation and…”
Get full text

Cellular resolution of inflammation-catabasis by Widgerow, Alan D.

“…Controlled inflammation has become a central focus in chronic disease therapeutics. Exaggerated inflammation is a common factor that contributes to matrix…”
Get full text

Implications for human adipose‐derived stem cells in plastic surgery by Banyard, Derek A., Salibian, Ara A., Widgerow, Alan D., Evans, Gregory R. D.

“…Adipose‐derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) that possess many of the same regenerative properties as other MSCs. However,…”
Get full text

Current concepts on burn wound conversion—A review of recent advances in understanding the secondary progressions of burns by Salibian, Ara A, Rosario, Angelica Tan Del, Severo, Lucio De Almeida Moura, Nguyen, Long, Banyard, Derek A, Toranto, Jason D, Evans, Gregory R.D, Widgerow, Alan D

“…Highlights • We review recent progress in the pathophysiology of burn wound conversion. • Halting burn progression will impact on the scar outcome and healing…”
Get full text

A Re-Examination of a Previous Study Relating to Topical Body Formulations: Validating Gene Expression Transcription at Multiple Time Points, and Protein Expression and Translation in an Ex Vivo Model by Widgerow, Alan D, Ziegler, Mary E, Shafiq, Faiza

“…Introduction: This study was conducted to question the findings of a prior study published in Journal of Drugs in Dermatology (JDD) in September 2023, which…”
Get full text

Topical oxygen therapy & micro/nanobubbles: a new modality for tissue oxygen delivery by Sayadi, Lohrasb R, Banyard, Derek A, Ziegler, Mary E, Obagi, Zaidal, Prussak, Jordyne, Klopfer, Michael J, Evans, Gregory RD, Widgerow, Alan D

“…Up to 15 billion dollars of US health care expenditure each year is consumed by treatment of poorly healing wounds whose etiologies are often associated with…”
Get full text

Stem cells in plastic surgery: a review of current clinical and translational applications by Salibian, Ara A, Widgerow, Alan D, Abrouk, Michael, Evans, Gregory Rd

“…Stem cells are a unique cell population characterized by self-renewal and cellular differentiation capabilities. These characteristics, among other traits,…”
Get full text

Topical Skin Treatment and Its Influence on Surgical Healing: Review of Literature and Underlying Physiology by Widgerow, Alan D, Ziegler, Mary E, Casas, Laurie A

“…Abstract TriHex Technology (Alastin Skincare, Carlsbad, CA) has been shown clinically to promote healing and outcomes post procedures and has been demonstrated…”
Get full text

Preparation, Characterization, and Clinical Implications of Human Decellularized Adipose Tissue Extracellular Matrix (hDAM): A Comprehensive Review by Banyard, Derek A., Borad, Vedant, Amezcua, Eduardo, Wirth, Garrett A., Evans, Gregory R.D., Widgerow, Alan D.

“…Fat grafting is commonly employed by plastic and reconstructive surgeons to address contour abnormalities and soft-tissue defects; however, because retention…”
Get full text

A Multi-Center Evaluation of Restorative Eye Treatment and INhance With Trihex Technology to Improve Aesthetic Outcomes When Used Pre- and Post-Blepharoplasty by Lee, Wendy W, Fagien, Steven, Murdock, Jennifer, Bell, Michaela, Widgerow, Alan D

“…Abstract Background Restorative Eye Treatment with TriHex Technology (RET) is a topical eye product with peptides and botanicals that reduce the appearance of…”
Get full text

Evaluating the Efficacy, Tolerability, and Outcomes of Topical Tripeptide/Hexapeptide Formulations Before and After Liposuction of the Medial Thighs by Claytor, Brannon, Casas, Laurie, Ziegler, Mary, Widgerow, Alan D, Bell, Michaela

“…Abstract Regenerating Skin Nectar with TriHex Technology (RSN) has been shown clinically to promote healing and outcomes post procedures. TransFORM Body…”
Get full text

So Let's Design a Peptide . . . A Physician's Approach by Widgerow, Alan D

“…This paper outlines a process undertaken by a physician to design a peptide aimed at impacting the extracellular matrix. From a position of very little…”
Get more information

An Analysis of Patient-Reported Recovery Outcomes of Topical Tripeptide/Hexapeptide Formulations Utilized in a Prospective Randomized Double-Blind Split Neck and Body Study by Casas, Laurie A, Bell, Michaela, Claytor, Brannon, Ziegler, Mary E, Widgerow, Alan D

“…Abstract Background Physicians strive to improve the postsurgical experience and optimize patient-reported recovery outcome measures (PROMs) following elective…”
Get full text

Microsurgical Needle Retention Does Not Cause Pain or Neurovascular Injury in a Rat Model by Arora, Jagmeet S, Kim, Joshua K, Pakvasa, Mikhail, Sayadi, Lohrasb R, Lem, Melinda, Widgerow, Alan D, Leis, Amber R

“…Approximately 20% of retained foreign bodies are surgical needles. Retained macro-needles may become symptomatic, but the effect of microsurgical needles is…”
Get full text

Ischemia-Reperfusion Injury: Influencing the Microcirculatory and Cellular Environment by Widgerow, Alan D

“…ABSTRACTIschemia-reperfusion injury forms the basis of tissue damage and cellular apoptosis in many pathologic and traumatic processes. The tissue damage…”
Get full text

Operating Room Stencil: A Novel Mobile Application for Surgical Planning by Sayadi, Lohrasb R., Chopan, Mustafa, Sayadi, Jamasb J., Samai, Aubtin, Arora, Jagmeet S., Anand, Suraj, Evans, Gregory, Widgerow, Alan D., Vyas, Raj

“…The techniques used to make preoperative markings before soft tissue reconstruction have remained relatively unchanged since the earliest years of plastic…”
Get full text

A Multicenter, Randomized, Double-Blind, Split-Body Clinical Trial Evaluating the Efficacy and Outcomes of a Topical Product Pre and Post Aesthetic Surgical Body Procedures by Casas, Laurie A, Claytor, R Brannon, Zeidler, Kamakshi R, Shridharani, Sachin M, Cohen, Steven R, Khanna, Julie J, Gould, Daniel J, Yates, Essie K, Lultschik, Shantel, Bell, Michaela, Widgerow, Alan D

“…Abstract Background Skin preconditioning prior to and following procedures, has previously been demonstrated to hasten and optimize healing, and decrease the…”
Get full text

New approaches to skin photodamage histology—Differentiating 'good' versus 'bad' Elastin by Widgerow, Alan D., Napekoski, Karl

“…Background Photodamage creates changes within the skin layers known as solar elastosis. This presents as fragmentation of collagen and elastin fibers,…”
Get full text