Search Results - "Widgerow, Alan"

So Let's Design a Peptide . . . A Physician's Approach by Widgerow, Alan D

“…This paper outlines a process undertaken by a physician to design a peptide aimed at impacting the extracellular matrix. From a position of very little…”
Get more information

Ischemia-Reperfusion Injury: Influencing the Microcirculatory and Cellular Environment by Widgerow, Alan D

“…ABSTRACTIschemia-reperfusion injury forms the basis of tissue damage and cellular apoptosis in many pathologic and traumatic processes. The tissue damage…”
Get full text

Regeneration of fat cells from myofibroblasts during wound healing by Plikus, Maksim V., Guerrero-Juarez, Christian F., Ito, Mayumi, Li, Yun Rose, Dedhia, Priya H., Zheng, Ying, Shao, Mengle, Gay, Denise L., Ramos, Raul, Hsi, Tsai-Ching, Oh, Ji Won, Wang, Xiaojie, Ramirez, Amanda, Konopelski, Sara E., Elzein, Arijh, Wang, Anne, Supapannachart, Rarinthip June, Lee, Hye-Lim, Lim, Chae Ho, Nace, Arben, Guo, Amy, Treffeisen, Elsa, Andl, Thomas, Ramirez, Ricardo N., Murad, Rabi, Offermanns, Stefan, Metzger, Daniel, Chambon, Pierre, Widgerow, Alan D., Tuan, Tai-Lan, Mortazavi, Ali, Gupta, Rana K., Hamilton, Bruce A., Millar, Sarah E., Seale, Patrick, Pear, Warren S., Lazar, Mitchell A., Cotsarelis, George

“…Although regeneration through the reprogramming of one cell lineage to another occurs in fish and amphibians, it has not been observed in mammals. We…”
Get full text

Chronic wound fluid-thinking outside the box by Widgerow, Alan David

“…ABSTRACT Chronic wounds are associated with an altered wound milieu that results from an imbalance in extracellular matrix (ECM) homeostasis. This alteration…”
Get full text

Cellular/extracellular matrix cross-talk in scar evolution and control by Widgerow, Alan D.

“…ABSTRACT The principles of scar evolution and control are recognized and defined. Further clarity has been shed on these principles with the elucidation and…”
Get full text

Stromal vascular fraction: A regenerative reality? Part 1: Current concepts and review of the literature by Nguyen, Andrew, Guo, James, Banyard, Derek A, Fadavi, Darya, Toranto, Jason D, Wirth, Garrett A, Paydar, Keyianoosh Z, Evans, Gregory R.D, Widgerow, Alan D

“…Summary Stromal Vascular Fraction (SVF) is a heterogeneous collection of cells contained within adipose tissue that is traditionally isolated using enzymes…”
Get full text

New approaches to skin photodamage histology—Differentiating 'good' versus 'bad' Elastin by Widgerow, Alan D., Napekoski, Karl

“…Background Photodamage creates changes within the skin layers known as solar elastosis. This presents as fragmentation of collagen and elastin fibers,…”
Get full text

Patient-Reported Satisfaction After Autologous Auricular Reconstruction in Patients with Microtia: A Systematic Review by Khan, Nawal, Willette, Dominique, Melkonian, Jacklyn, Ziegler, Mary, Widgerow, Alan D

“…In a patient-centered field such as plastic surgery, patient-reported satisfaction can measure the success and value of surgery, since it is not uncommon for…”
Get more information

Cellular resolution of inflammation-catabasis by Widgerow, Alan D.

“…Controlled inflammation has become a central focus in chronic disease therapeutics. Exaggerated inflammation is a common factor that contributes to matrix…”
Get full text

Fluidic Device System for Mechanical Processing and Filtering of Human Lipoaspirate Enhances Recovery of Mesenchymal Stem Cells by Lombardo, Jeremy A., Banyard, Derek A., Widgerow, Alan D., Haun, Jered B.

“…Adipose tissue is an easily accessible source of stem and progenitor cells that offers exciting promise as an injectable autologous therapeutic for…”
Get full text

Multicenter evaluation of a topical antioxidant serum by Moradi, Amir, Shafiq, Faiza, Robison, Tiffany, Colvan, Lora, Poehler, Jeannette, Widgerow, Alan D.

“…Background A new antioxidant serum has been formulated with sodium ascorbate, a sodium salt of Vit C, which aims to address facial photodamage while…”
Get full text

Vitamin C, lactoferrin and elastin—Advancing the science by Widgerow, Alan D., Ziegler, Mary E.

“…Background This study follows an initial scientific validation linking sodium ascorbate (SAC) with elastin conservation and the clinical trial histology…”
Get full text

Elucidating the Preadipocyte and Its Role in Adipocyte Formation: a Comprehensive Review by Sarantopoulos, Christos N., Banyard, Derek A., Ziegler, Mary E., Sun, Beatrice, Shaterian, Ashkaun, Widgerow, Alan D.

“…Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is converted to a preadipocyte before terminal differentiation into the…”
Get full text

Pain mediators and wound healing—Establishing the connection by Widgerow, Alan D, Kalaria, Shana

“…Abstract Pain accompanies every disruption of the skin surface in a normal sensate individual. The intensity and duration of the pain varies depending on the…”
Get full text

Implications for human adipose‐derived stem cells in plastic surgery by Banyard, Derek A., Salibian, Ara A., Widgerow, Alan D., Evans, Gregory R. D.

“…Adipose‐derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) that possess many of the same regenerative properties as other MSCs. However,…”
Get full text

Antioxidants with proven efficacy and elastin‐conserving vitamin C—A new approach to free radical defense by Widgerow, Alan D., Ziegler, Mary E., Garruto, John A., Shafiq, Faiza

“…Background This paper describes the background research and validation related to the formulation of a novel antioxidant product. Two defined outcomes were…”
Get full text

Developing a Topical Adjunct to Injectable Procedures by Widgerow, Alan D, Jacob, Carolyn, Palm, Melanie D, Garruto, John A, Bell, Michaela

“…Injectable procedures have come to play an enormous part in everyday aesthetic medical practice. Whether its use is directed at volumizing with fillers,…”
Get more information

Current concepts on burn wound conversion—A review of recent advances in understanding the secondary progressions of burns by Salibian, Ara A, Rosario, Angelica Tan Del, Severo, Lucio De Almeida Moura, Nguyen, Long, Banyard, Derek A, Toranto, Jason D, Evans, Gregory R.D, Widgerow, Alan D

“…Highlights • We review recent progress in the pathophysiology of burn wound conversion. • Halting burn progression will impact on the scar outcome and healing…”
Get full text

Stromal vascular fraction: A regenerative reality? Part 2: Mechanisms of regenerative action by Guo, James, Nguyen, Andrew, Banyard, Derek A, Fadavi, Darya, Toranto, Jason D, Wirth, Garrett A, Paydar, Keyianoosh Z, Evans, Gregory R.D, Widgerow, Alan D

“…Summary Adipose tissue is a rich source of cells with emerging promise for tissue engineering and regenerative medicine. The stromal vascular fraction (SVF),…”
Get full text

Identification of a Regenerative Protocol for Recellularizing Human Auricular Cartilage Scaffolds by Ziegler, Mary E, Alaniz, Leonardo, Khan, Nawal, Lem, Melinda, Pham, Jason, Sherafat, Arya, Melkonian, Jacklyn, Prabhakar, Nikhil, Shay, Madelyn, Oyur, Kadir B, Pfaff, Miles J, Widgerow, Alan D

“…Utilizing biological scaffolds for cartilage tissue engineering is a promising tool for improving auricular reconstruction. Decellularized auricular scaffolds…”
Get full text