Search Results - "Widge, Alik S."

Deep brain stimulation for psychiatric disorders: From focal brain targets to cognitive networks by Sullivan, Christi R.P., Olsen, Sarah, Widge, Alik S.

“…•DBS is a promising therapy for OCD and MDD but still has variable clinical outcomes.•We propose that a sharper focus on network effects of DBS may improve…”
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Closed-Loop Deep Brain Stimulation for Psychiatric Disorders by Widge, Alik S.

“…Deep brain stimulation (DBS) is a well-established approach to treating medication-refractory neurological disorders and holds promise for treating psychiatric…”
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tDCS to the left DLPFC modulates cognitive and physiological correlates of executive function in a state-dependent manner by Dubreuil-Vall, Laura, Chau, Peggy, Ruffini, Giulio, Widge, Alik S., Camprodon, Joan A.

“…The use of transcranial Direct Current Stimulation (tDCS) to study anatomical and physiological dynamics and circuits supporting cognition and executive…”
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Electroencephalographic Biomarkers for Treatment Response Prediction in Major Depressive Illness: A Meta-Analysis by Widge, Alik S, Bilge, M. Taha, Montana, Rebecca, Chang, Weilynn, Rodriguez, Carolyn I, Deckersbach, Thilo, Carpenter, Linda L, Kalin, Ned H, Nemeroff, Charles B

“…Objective:Reducing unsuccessful treatment trials could improve depression treatment. Quantitative EEG (QEEG) may predict treatment response and is being…”
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A Shared Vision for Machine Learning in Neuroscience by Vu, Mai-Anh T, Adalı, Tülay, Ba, Demba, Buzsáki, György, Carlson, David, Heller, Katherine, Liston, Conor, Rudin, Cynthia, Sohal, Vikaas S, Widge, Alik S, Mayberg, Helen S, Sapiro, Guillermo, Dzirasa, Kafui

“…With ever-increasing advancements in technology, neuroscientists are able to collect data in greater volumes and with finer resolution. The bottleneck in…”
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Low-Intensity Transcranial Current Stimulation in Psychiatry by Philip, Noah S, Nelson, Brent G, Frohlich, Flavio, Lim, Kelvin O, Widge, Alik S, Carpenter, Linda L

“…Neurostimulation is rapidly emerging as an important treatment modality for psychiatric disorders. One of the fastest-growing and least-regulated approaches to…”
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Closing the Loop on Deep Brain Stimulation for Treatment-Resistant Depression by Widge, Alik S, Malone, Jr, Donald A, Dougherty, Darin D

“…Major depressive episodes are the largest cause of psychiatric disability, and can often resist treatment with medication and psychotherapy. Advances in the…”
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Evaluating the Machine Learning Literature: A Primer and User’s Guide for Psychiatrists by Grzenda, Adrienne, Kraguljac, Nina V, McDonald, William M, Nemeroff, Charles, Torous, John, Alpert, Jonathan E, Rodriguez, Carolyn I, Widge, Alik S

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Social media recruitment for mental health research: A systematic review by Sanchez, Catherine, Grzenda, Adrienne, Varias, Andrea, Widge, Alik S., Carpenter, Linda L., McDonald, William M., Nemeroff, Charles B., Kalin, Ned H., Martin, Glenn, Tohen, Mauricio, Filippou-Frye, Maria, Ramsey, Drew, Linos, Eleni, Mangurian, Christina, Rodriguez, Carolyn I.

“…Social media holds exciting promise for advancing mental health research recruitment, however, the extent and efficacy to which these platforms are currently…”
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Local and distant responses to single pulse electrical stimulation reflect different forms of connectivity by Crocker, Britni, Ostrowski, Lauren, Williams, Ziv M., Dougherty, Darin D., Eskandar, Emad N., Widge, Alik S., Chu, Catherine J., Cash, Sydney S., Paulk, Angelique C.

“…Measuring connectivity in the human brain involves innumerable approaches using both noninvasive (fMRI, EEG) and invasive (intracranial EEG or iEEG) recording…”
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A state space modeling approach to real-time phase estimation by Wodeyar, Anirudh, Schatza, Mark, Widge, Alik S, Eden, Uri T, Kramer, Mark A

“…Brain rhythms have been proposed to facilitate brain function, with an especially important role attributed to the phase of low-frequency rhythms…”
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CLoSES: A platform for closed-loop intracranial stimulation in humans by Zelmann, Rina, Paulk, Angelique C., Basu, Ishita, Sarma, Anish, Yousefi, Ali, Crocker, Britni, Eskandar, Emad, Williams, Ziv, Cosgrove, G. Rees, Weisholtz, Daniel S., Dougherty, Darin D., Truccolo, Wilson, Widge, Alik S., Cash, Sydney S.

“…Targeted interrogation of brain networks through invasive brain stimulation has become an increasingly important research tool as well as therapeutic modality…”
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Prefrontal cortex and cognitive control: new insights from human electrophysiology [version 1; peer review: 3 approved] by Widge, Alik S, Heilbronner, Sarah R, Hayden, Benjamin Y

“…Cognitive control, the ability to regulate one's cognition and actions on the basis of over-riding goals, is impaired in many psychiatric conditions. Although…”
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Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters by Paulk, Angelique C., Zelmann, Rina, Crocker, Britni, Widge, Alik S., Dougherty, Darin D., Eskandar, Emad N., Weisholtz, Daniel S., Richardson, R. Mark, Cosgrove, G. Rees, Williams, Ziv M., Cash, Sydney S.

“…Electrical neuromodulation via direct electrical stimulation (DES) is an increasingly common therapy for a wide variety of neuropsychiatric diseases…”
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A Bayesian Gaussian Process-Based Latent Discriminative Generative Decoder (LDGD) Model for High-Dimensional Data by Ziaei, Navid, Nazari, Behzad, Eden, Uri T., Widge, Alik S., Yousefi, Ali

“…Extracting meaningful information from high-dimensional data poses a formidable modeling challenge, particularly when the data is obscured by noise or…”
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Altering alpha-frequency brain oscillations with rapid analog feedback-driven neurostimulation by Widge, Alik S, Boggess, Matthew, Rockhill, Alexander P, Mullen, Andrew, Sheopory, Shivani, Loonis, Roman, Freeman, Daniel K, Miller, Earl K

“…Oscillations of the brain's local field potential (LFP) may coordinate neural ensembles and brain networks. It has been difficult to causally test this model…”
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Case Report of Dual-Site Neurostimulation and Chronic Recording of Cortico-Striatal Circuitry in a Patient With Treatment Refractory Obsessive Compulsive Disorder by Olsen, Sarah T, Basu, Ishita, Bilge, Mustafa Taha, Kanabar, Anish, Boggess, Matthew J, Rockhill, Alexander P, Gosai, Aishwarya K, Hahn, Emily, Peled, Noam, Ennis, Michaela, Shiff, Ilana, Fairbank-Haynes, Katherine, Salvi, Joshua D, Cusin, Cristina, Deckersbach, Thilo, Williams, Ziv, Baker, Justin T, Dougherty, Darin D, Widge, Alik S

“…Psychiatric disorders are increasingly understood as dysfunctions of hyper- or hypoconnectivity in distributed brain circuits. A prototypical example is…”
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Closing the loop in psychiatric deep brain stimulation: physiology, psychometrics, and plasticity by Widge, Alik S

“…Deep brain stimulation (DBS) is an invasive approach to precise modulation of psychiatrically relevant circuits. Although it has impressive results in…”
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A Sub-millimeter, Inductively Powered Neural Stimulator by Freeman, Daniel K, O'Brien, Jonathan M, Kumar, Parshant, Daniels, Brian, Irion, Reed A, Shraytah, Louis, Ingersoll, Brett K, Magyar, Andrew P, Czarnecki, Andrew, Wheeler, Jesse, Coppeta, Jonathan R, Abban, Michael P, Gatzke, Ronald, Fried, Shelley I, Lee, Seung Woo, Duwel, Amy E, Bernstein, Jonathan J, Widge, Alik S, Hernandez-Reynoso, Ana, Kanneganti, Aswini, Romero-Ortega, Mario I, Cogan, Stuart F

“…Wireless neural stimulators are being developed to address problems associated with traditional lead-based implants. However, designing wireless stimulators on…”
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Lost in translation: no effect of repeated optogenetic cortico-striatal stimulation on compulsivity in rats by de Oliveira, Amanda R., Reimer, Adriano E., Simandl, Gregory J., Nagrale, Sumedh S., Widge, Alik S.

“…The orbitofrontal cortex–ventromedial striatum (OFC–VMS) circuitry is widely believed to drive compulsive behavior. Hyperactivating this pathway in inbred mice…”
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