Search Results - "Wideł, Maria"

Induction of bystander effects by UVA, UVB, and UVC radiation in human fibroblasts and the implication of reactive oxygen species by Widel, Maria, Krzywon, Aleksandra, Gajda, Karolina, Skonieczna, Magdalena, Rzeszowska-Wolny, Joanna

“…Radiation-induced bystander effects are various types of responses displayed by nonirradiated cells induced by signals transmitted from neighboring irradiated…”
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Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy by Rzeszowska-Wolny, Joanna, Przybyszewski, Waldemar M., Widel, Maria

“…Cells exposed to ionizing radiation show DNA damage, apoptosis, chromosomal aberrations or increased mutation frequency and for a long time it was generally…”
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Modifying effect of vitamins C, E and beta-carotene against gamma-ray-induced DNA damage in mouse cells by Konopacka, Maria, Widel, Maria, Rzeszowska-Wolny, Joanna

“…The modifying effect of treatment with vitamins C, E and beta-carotene on the clastogenic activity of gamma rays was investigated in mice. Damage in vivo was…”
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Bystander Me45 Melanoma Cells Increase Damaging Effect in UVC‐irradiated Cells by Krzywon, Aleksandra, Widel, Maria

“…The aim of our study was to investigate the possible mechanism(s) of the bystander effect induced by UVC light in malignant melanoma Me45 cells that were…”
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Dose rate-dependent cellular and molecular effects of ionizing radiation by Przybyszewski, Waldemar M, Wideł, Maria, Szurko, Agnieszka, Maniakowski, Zbigniew

“…The aim of radiation therapy is to kill tumor cells while minimizing damage to normal cells. The ultimate effect of radiation can be apoptotic or necrotic cell…”
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Bystander effect induced by UV radiation; why should we be interested? by Widel, Maria

“…The bystander effect, whose essence is an interaction of cells directly subjected to radiation with adjacent non-subjected cells, via molecular signals, is an…”
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CYTOKINESIS-BLOCK MICRONUCLEUS ASSAY IN HUMAN GLIOMA CELLS EXPOSED TO RADIATION by Slowinski, Jerzy, Bierzynska-Macyszyn, Grazyna, Mazurek, Urszula, Widel, Maria, Latocha, Malgorzata, Stomal, Monika, Snietura, Miroslaw, Mrowka, Ryszard

“…Biological tests are efficient in reflecting the biological influences of several types of generally harmful exposures. The micronucleus assay is widely used…”
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Radiation-induced bystander effect: the important part of ionizing radiation response. Potential clinical implications by Wideł, Maria, Przybyszewski, Waldemar, Rzeszowska-Wolny, Joanna

“…It has long been a central radiobiological dogma that the damaging effects of ionizing radiation, such as cell death, cytogenetic changes, apoptosis,…”
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Connecting Radiation-Induced Bystander Effects and Senescence to Improve Radiation Response Prediction by Poleszczuk, Jan, Krzywon, Aleksandra, Forys, Urszula, Widel, Maria

“…For the last two decades radiation-induced bystander effects (RIBEs) have attracted significant attention due to their possible implications for radiotherapy…”
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Modulation by neighboring cells of the responses and fate of melanoma cells irradiated with UVA by Krzywon, Aleksandra, Widel, Maria, Fujarewicz, Krzysztof, Skonieczna, Magdalena, Rzeszowska-Wolny, Joanna

“…UVA radiation, which accounts for about 95% of the solar spectrum, contributes to and may be the etiological factor of skin cancers of which malignant melanoma…”
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Mechanisms of metastasis and molecular markers of malignant tumor progression. I. Colorectal cancer by Wideł, Maciej S, Wideł, Maria

“…The ability of neoplastic cells to dissemination from a primary tumor to lymphatic nodes and to adjacent and distant tissues and organs is an inseparable…”
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The influence of XPD, APE1, XRCC1, and NBS1 polymorphic variants on DNA repair in cells exposed to X-rays by Gdowicz-Klosok, Agnieszka, Widel, Maria, Rzeszowska-Wolny, Joanna

“…•Polymorphisms in DNA repair genes may change the risk of cancer development•We show that XPD and XRCC1 polymorphisms influence cell responses to X-rays•XPD…”
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Inverse Dose-Rate Effect for the Induction of Micronuclei in Lewis Lung Carcinoma after Exposure to Cobalt-60 Gamma Rays by Wideł, Maria, Przybyszewski, Waldemar M.

“…Induction of micronuclei was used as a measure of the dose-rate effect in Lewis lung carcinoma in vivo. Tumors transplanted on the hind legs of male C57BL mice…”
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The different radiation response and radiation-induced bystander effects in colorectal carcinoma cells differing in p53 status by Widel, Maria, Lalik, Anna, Krzywon, Aleksandra, Poleszczuk, Jan, Fujarewicz, Krzysztof, Rzeszowska-Wolny, Joanna

“…Radiation-induced bystander effect, appearing as different biological changes in cells that are not directly exposed to ionizing radiation but are under the…”
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Photodynamic effects of two water soluble porphyrins evaluated on human malignant melanoma cells in vitro by Szurko, Agnieszka, Krämer-Marek, Gabriela, Wideł, Maria, Ratuszna, Alicja, Habdas, Jan, Kuś, Piotr

“…Two water soluble porphyrins: meso-tetra-4-N-methylpyridyl-porphyrin iodide (P1) and 5,10-di-(4-acetamidophenyl)-15,20-di-(4-N-methylpyridyl) porphyrin (P2)…”
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Apoptosis and clonogenic survival in three tumour cell lines exposed to gamma rays or chemical genotoxic agents by Kumala, Sławomir, Niemiec, Paweł, Wideł, Maria, Hancock, Ronald, Rzeszowska-Wolny, Joanna

“…We compared the extent to which apoptosis is induced and clonogenicity reduced in three tumour cell lines - the human melanoma Me45 and promyelocytic leukaemia…”
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Cardiotoxic consequences of ionizing radiation and anthracyclines by Przybyszewski, Waldemar M, Wideł, Maria, Rzeszowska-Wolny, Joanna

“…The mechanisms of the toxic side effects of radiation and anthracyclines are generally based on free radical reactions. Target molecules for free radicals are…”
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X-irradiation and bystander effects induce similar changes of transcript profiles in most functional pathways in human melanoma cells by Rzeszowska-Wolny, Joanna, Herok, Robert, Widel, Maria, Hancock, Ronald

“…Unirradiated cells which neighbor cells exposed to ionizing radiation (IR) show responses termed bystander effects, including DNA damage, chromosomal…”
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Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy: New Vistas in Anti-Cancer Therapy by RZESZOWSKA-WOLNY, Joanna, PRZYBYSZEWSKI, Waldemar M, WIDEL, Maria

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PEROXIDATIVE CHANGES IN RAT MYOCARDIUM PRODUCED BY GAMMA RAYS OR FARMORUBICIN: PREVENTION BY CARDIOXANE OR NEOTON by Waldemar M. Przybyszewski, Maria Widel Aleksandra Koterbicka

“…This investigation reports a lack of antioxidant capacity of drugs used as cardioprotectors, Cardioxane and Neoton, to prevent peroxidative heart damage…”
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