Search Results - "Wicomb, W N"

Prevention of Myocardial Injury During Brain Death by Total Cardiac Sympathectomy in the Chacma Baboon by Novitzky, D., Wicomb, W.N., Cooper, D. K.C., Rose, A.G., Reichart, B.

“…In a previous study, structural myocardial damage was found to occur in 60% of baboons after brain death had been induced by a rapid increase in intracranial…”
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Liver transplantation from non–heart beating donors in rats: Influence of viscosity and temperature of initial flushing solutions on graft function by Tojimbara, T, Wicomb, W N, Garcia‐Kennedy, R, Burns, W, Hayashi, M, Collins, G, Esquivel, C O

“…Background: We evaluated the effect of warm (37 degrees C) versus cold (4 degrees C) solutions as the initial flush for liver preservation from non‐heart…”
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24-hour rabbit heart storage with UW solution. Effects of low-flow perfusion, colloid, and shelf storage by Wicomb, W N, Collins, G M

“…A new technique for 24-hr cardiac preservation is described utilizing very low flow perfusion (microperfusion) with a cold flush solution. Rabbit hearts were…”
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Optimal cardioplegia and 24-hour heart storage with simplified UW solution containing polyethylene glycol by Wicomb, W N, Hill, J D, Avery, J, Collins, G M

“…Recent work has shown that UW may be better than standard cardioplegic solutions for short-term heart preservation. In this study we have used a rabbit heart…”
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Evaluation of a portable hypothermic microperfusion system for storage of the donor heart: Clinical experience by Hill, D.J., Wicomb, W.N., Avery, G.J., Portnoy, V.F., Collins, G.M.

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The pathophysiological effects of brain death on potential donor organs, with particular reference to the heart by Cooper, D K, Novitzky, D, Wicomb, W N

“…Major electrocardiographic, haemodynamic, and histopathological changes take place during the development of brain death; myocardial and pulmonary injury may…”
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Heart preservation solution containing polyethyleneglycol: an immunosuppressive effect? by Collins, G M, Wicomb, W N, Levin, B S, Verma, S, Avery, J, Hill, J D

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Evaluation of unstored hearts: Immediate functional differences between St Thomas, UW, and cardiosol following cardioplegia by Wicomb, W.N., Collins, G.M.

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New organ preservation solutions by Collins, G M, Wicomb, W N

“…In 1969 we described a method for kidney preservation that used a brief flush with a new "intracellular" solution followed by ice storage. This paper…”
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The effects of brain death and 24 hours' storage by hypothermic perfusion on donor heart function in the pig by Wicomb, W N, Cooper, D K, Lanza, R P, Novitzky, D, Isaacs, S

“…The effects on the myocardium of the agonal period and subsequent management have been studied in the pig. Acute ischemia of the brain led to major temporary…”
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Choice of cation in solutions for hypothermic storage of liver and heart. High-sodium versus high-potassium by Wicomb, W N, Collins, A B, Tokunaga, Y, Esquivel, C

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Cardiac Transplantation Following Storage of the Donor Heart by a Portable Hypothermic Perfusion System by Wicomb, W.N., Cooper, D.K.C., Novitzky, D., Barnard, C.N.

“…Four patients have undergone heterotopic heart transplantation with donor hearts stored by a portable hypothermic perfusion system. Total ischemic periods…”
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Modification of rejection by polyethylene glycol in small bowel transplantation by Itasaka, H, Burns, W, Wicomb, W N, Egawa, H, Collins, G, Esquivel, C O

“…The use of polyethylene glycol (PEG) in preservation solutions has been associated with a decreased incidence of rejection in clinical and experimental organ…”
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Twenty-four-hour ice storage of rabbit heart by Wicomb, W N, Hill, D J, Collins, G M

“…Although cardioplegia is limited to 4 hours of ice storage, University of Wisconsin solution has successfully extended this period to approximately 12 hours…”
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Successful 20-hour rat liver preservation with chlorpromazine in sodium lactobionate sucrose solution by Tokunaga, Y, Wicomb, W N, Concepcion, W, Nakazato, P, Collins, G M, Esquivel, C O

“…We investigated the effect of the addition of chlorpromazine to a new, simplified organ preservation solution, sodium lactobionate sucrose (SLS), for 20-hour…”
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Improved cardiac function following hormonal therapy in brain dead pigs: relevance to organ donation by Novitzky, D, Wicomb, W N, Cooper, D K, Tjaalgard, M A

“…Deterioration of function in brain dead baboons is associated with depletion of both myocardial energy stores and certain circulating hormones, notably…”
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Pathophysiology of Pulmonary Edema Following Experimental Brain Death in the Chacma Baboon by Novitzky, D., Wicomb, W.N., Rose, A.G., Cooper, D.K.C., Reichart, B.

“…Systemic and pulmonary hemodynamics have been studied during the induction of brain death in the chacma baboon. In 11 animals brain death was induced by acute…”
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Impairment of renal slice function following brain death, with reversibility of injury by hormonal therapy by Wicomb, W N, Cooper, D K, Novitzky, D

“…The effects of the agonal period and subsequent donor management on renal slice function, using the K+ - Na+ ratio, have been studied in the pig. Brain…”
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Cardiotonic effects of reduced sulfhydryl amines after preservation of rabbit hearts by Holdefer, M M, Wicomb, W N, Levy, J V, Collins, G M

“…This investigation was designed to examine the role of glutathione and other reduced sulfhydryl amines during reperfusion of the ischemic rabbit heart. To…”
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Canine and cadaver kidney preservation with sodium lactobionate sucrose solution by Collins, G M, Wicomb, W N, Warren, R, Wong, L, Bry, W I, Feduska, N J, Salvatierra, O

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