Search Results - "Wicks, I"

Atorvastatin reduces arterial stiffness in patients with rheumatoid arthritis by Van Doornum, S, McColl, G, Wicks, I P

“…Background: Chronic systemic inflammation may contribute to accelerated atherosclerosis and increased arterial stiffness in patients with rheumatoid arthritis…”
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Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling by Liu, X., D'Cruz, A.A., Hansen, J., Croker, B.A., Lawlor, K.E., Sims, N.A., Wicks, I.P.

“…To investigate the impact of deleting Suppressor of Cytokine Signaling (SOCS)-3 (SOCS3) in chondrocytes during murine skeletal development. Mice with a…”
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Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis by Greven, D E A, Cohen, E S, Gerlag, D M, Campbell, J, Woods, J, Davis, N, van Nieuwenhuijze, A, Lewis, A, Heasmen, S, McCourt, M, Corkill, D, Dodd, A, Elvin, J, Statache, G, Wicks, I P, Anderson, I K, Nash, A, Sleeman, M A, Tak, P P

“…Previous work has suggested that the granulocyte macrophage colony stimulating factor (GM-CSF)-GM-CSF receptor α axis (GM-CSFRα) may provide a new therapeutic…”
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Tumour necrosis factor antagonists improve disease activity but not arterial stiffness in rheumatoid arthritis by Van Doornum, S., McColl, G., Wicks, I. P.

“…Objectives. Systemic inflammation may play an important role in the accelerated atherosclerosis and increased cardiovascular mortality of rheumatoid arthritis…”
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Primary angiitis of the central nervous system: experience of a Victorian tertiary-referral hospital by Oon, S., Roberts, C., Gorelik, A., Wicks, I., Brand, C.

“…Background Primary angiitis of the central nervous system is a rare condition, which is often difficult to diagnose and is associated with significant…”
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Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3 by Liu, X, Liu, R, Croker, B.A, Lawlor, K.E, Smyth, G.K, Wicks, I.P

“…Summary Objective To describe gene expression in murine chondrocytes stimulated with IL-6 family cytokines and the impact of deleting Suppressor of Cytokine…”
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Mixed methods evaluation of a comprehensive osteoarthritis hip and knee service; patient, clinician and administrative perspectives by Cavka, B, Ackerman, I, Tacey, M, Wicks, I, Bucknill, A, Brand, C.A

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Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress by Iyo, A.H, Kieran, N, Chandran, A, Albert, P.R, Wicks, I, Bissette, G, Austin, M.C

“…Abstract Chronic stress is known to affect brain areas involved in learning and emotional responses. These changes, thought to be related to the development of…”
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Severe inflammatory arthritis and lymphadenopathy in the absence of TNF by Campbell, I K, O'Donnell, K, Lawlor, K E, Wicks, I P

“…It has been postulated that TNF has a pivotal role in a cytokine cascade that results in joint inflammation and destruction in rheumatoid arthritis (RA). To…”
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Vascular cell adhesion molecule‐1 (VCAM‐1) blockade in collagen‐induced arthritis reduces joint involvement and alters B cell trafficking by CARTER, R. A., CAMPBELL, I. K., O’DONNEL, K. L., WICKS, I. P.

“…SUMMARY Vascular cell adhesion molecule‐1 (VCAM‐1 or CD106) is important in leucocyte trafficking and its increased expression is associated with a number of…”
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Expression of Receptor Tyrosine Kinase Axl and its Ligand Gas6 in Rheumatoid Arthritis : Evidence for a Novel Endothelial Cell Survival Pathway by O'Donnell, Kristy, Harkes, Inge Clara, Dougherty, Loretta, Wicks, Ian Peter

“…Angiogenesis and synovial cell hyperplasia are characteristic features of rheumatoid arthritis (RA). Many growth and survival factors use receptors belonging…”
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Prolonged prodrome, systemic vasculitis, and deafness in Cogan's syndrome by Van Doornum, S, McColl, G, Walter, M, Jennens, I, Bhathal, P, Wicks, I P

“…Cogan's syndrome is a rare, multisystem disease which occurs predominantly in children and young adults. It was originally described as the combination of…”
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Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation by Egan, P J, Lawlor, KE, Alexander, W S, Wicks, I P

“…Suppressor of cytokine signaling-1 (SOCS-1) is a negative regulator of cytokine signaling. To investigate the role of SOCS-1 in regulating inflammatory and…”
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Collagen‐induced arthritis in C57BL/6 (H‐2b) mice: new insights into an important disease model of rheumatoid arthritis by Campbell, Ian K., Hamilton, John A., Wicks, Ian P.

“…Collagen‐induced arthritis (CIA) is a widely used model of rheumatoid arthritis (RA) and has been important for understanding autoimmunity. CIA is purportedly…”
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Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation by Ernst, M, Inglese, M, Waring, P, Campbell, I K, Bao, S, Clay, F J, Alexander, W S, Wicks, I P, Tarlinton, D M, Novak, U, Heath, J K, Dunn, A R

“…The receptor subunit gp130 transduces multiple cell type-specific activities of the leukemia inhibitory factor (LIF)/interleukin (IL)-6 family of cytokines…”
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Accelerated atherosclerosis: An extraarticular feature of rheumatoid arthritis? by Van Doornum, S., McColl, G., Wicks, I. P.

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Molecular Cloning of HEK, the Gene Encoding a Receptor Tyrosine Kinase Expressed by Human Lymphoid Tumor Cell Lines by Wicks, I. P., Wilkinson, D., Salvaris, E., Boyd, A. W.

“…We describe the molecular cloning of a receptor tyrosine kinase from a cell line (LK63) derived from a case of human pre-B-cell leukemia. We have previously…”
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The role of the LFA-1/ICAM-1 interaction in human leukocyte homing and adhesion by Wawryk, S O, Novotny, J R, Wicks, I P, Wilkinson, D, Maher, D, Salvaris, E, Welch, K, Fecondo, J, Boyd, A W

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Intracardiac thrombosis complicating antiphospholipid antibody syndrome by Lim, E., Wicks, I., Roberts, L. J.

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Gross abdominal lymphadenopathy in sarcoidosis by Östör, A. J. K., Moran, H., Wicks, I. P.

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