CyVerse: Cyberinfrastructure for open science

CyVerse, the largest publicly-funded open-source research cyberinfrastructure for life sciences, has played a crucial role in advancing data-driven research since the 2010s. As the technology landscape evolved with the emergence of cloud computing platforms, machine learning and artificial intellige...

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Published in:PLoS computational biology Vol. 20; no. 2; p. e1011270
Main Authors: Swetnam, Tyson L, Antin, Parker B, Bartelme, Ryan, Bucksch, Alexander, Camhy, David, Chism, Greg, Choi, Illyoung, Cooksey, Amanda M, Cosi, Michele, Cowen, Cindy, Culshaw-Maurer, Michael, Davey, Robert, Davey, Sean, Devisetty, Upendra, Edgin, Tony, Edmonds, Andy, Fedorov, Dmitry, Frady, Jeremy, Fonner, John, Gillan, Jeffrey K, Hossain, Iqbal, Joyce, Blake, Lang, Konrad, Lee, Tina, Littin, Shelley, McEwen, Ian, Merchant, Nirav, Micklos, David, Nelson, Andrew, Ramsey, Ashley, Roberts, Sarah, Sarando, Paul, Skidmore, Edwin, Song, Jawon, Sprinkle, Mary Margaret, Srinivasan, Sriram, Stanzione, Dan, Strootman, Jonathan D, Stryeck, Sarah, Tuteja, Reetu, Vaughn, Matthew, Wali, Mojib, Wall, Mariah, Walls, Ramona, Wang, Liya, Wickizer, Todd, Williams, Jason, Wregglesworth, John, Lyons, Eric
Format: Journal Article
Language:English
Published: United States Public Library of Science 01-02-2024
Public Library of Science (PLoS)
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Summary:CyVerse, the largest publicly-funded open-source research cyberinfrastructure for life sciences, has played a crucial role in advancing data-driven research since the 2010s. As the technology landscape evolved with the emergence of cloud computing platforms, machine learning and artificial intelligence (AI) applications, CyVerse has enabled access by providing interfaces, Software as a Service (SaaS), and cloud-native Infrastructure as Code (IaC) to leverage new technologies. CyVerse services enable researchers to integrate institutional and private computational resources, custom software, perform analyses, and publish data in accordance with open science principles. Over the past 13 years, CyVerse has registered more than 124,000 verified accounts from 160 countries and was used for over 1,600 peer-reviewed publications. Since 2011, 45,000 students and researchers have been trained to use CyVerse. The platform has been replicated and deployed in three countries outside the US, with additional private deployments on commercial clouds for US government agencies and multinational corporations. In this manuscript, we present a strategic blueprint for creating and managing SaaS cyberinfrastructure and IaC as free and open-source software.
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The authors have declared that no competing interests exist.
Current address: The University of Arizona, Tucson, Arizona, United States of America
ISSN:1553-7358
1553-734X
1553-7358
DOI:10.1371/journal.pcbi.1011270