Search Results - "Wickham, N. W."

HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia lymphoma cells, and enhances cytarabine-induced cell death by LICKLITER, J. D, WOOD, N. J, JOHNSON, L, MCHUGH, G, TAN, J, WOOD, F, COX, J, WICKHAM, N. W

“…The Bcl-2 oncoprotein is commonly overexpressed in hematological malignancy, where it promotes the survival of neoplastic cells. Recently, a small molecule…”
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Fatal Penicillium citrinum pneumonia with pericarditis in a patient with acute leukemia by MOK, T, KOEHLER, A. P, YU, M. Y, ELLIS, D. H, JOHNSON, P. J, WICKHAM, N. W. R

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Frequent hypermethylation of p16 and p15 genes in multiple myeloma by NG, M. H. L, CHUNG, Y. F, LO, K. W, WICKHAM, N. W. R, LEE, J. C. K, HUANG, D. P

“…Both p16 and p15, encoded by the genes located on chromosome 9p21, are inhibitors of cyclin-dependent kinases (CDK4/6) and the upstream regulators of Rb…”
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Thrombin-treated endothelium primes neutrophil functions: inhibition by platelet-activating factor receptor antagonists by Vercellotti, G M, Wickham, N W, Gustafson, K S, Yin, H Q, Hebert, M, Jacob, H S

“…We have shown previously that fluid phase platelet-activating factor (PAF) can enhance or "prime" polymorphonuclear (PMN) responses to subsequent stimulation…”
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Upper airway obstruction caused by acquired inhibitor to factor VIII by Joynt, G M, Wickham, N W, Young, R J, Gomersall, C D

“…Bleeding caused by inhibitors to factor VIII is a rare medical emergency requiring immediate specialist investigation and management. Urgent initiation of…”
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Successful treatment of carbimazole-induced agranulocytosis and severe sepsis with granulocyte macrophage colony stimulating factor by FREEBAIRN, R. C, YOUNG, R. J, GOMERSALL, C. D, WICKHAM, N. W. R, CRITCHLEY, J. A. J. H

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Endogenous and Exogenous Adenosine Inhibit Granulocyte Aggregation Without Altering the Associated Rise in Intracellular Calcium Concentration by Skubitz, Keith M., Wickham, Nicholas W., Hammerschmidt, Dale E.

“…The effects of adenosine, adenosine deaminase (ADA), and an irreversible ADA inhibitor 2'-deoxycoformycin (DCF) on granulocyte aggregation in response to four…”
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Monoclonal gammopathy of unknown significance and malignant paraproteinemia in Hong Kong by LOLIN, Y. I, CHOW, J, WICKHAM, N. W. R

“…The incidence of multiple myeloma is lower in Southeast Asia than in the West. However, there are few reports on the overall incidence of paraproteinemia and…”
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Combined Morphological and Interphase Fluorescence in Situ Hybridization Study in Multiple Myeloma of Chinese Patients by Ng, Margaret Heung-Ling, Kan, Amanda, Chung, Yuk-Fei, Wong, Ivy Hing-Nam, Lo, Kwok-Wai, Wickham, Nicolas William Rupert, Lei, Kenny Ieng-Kit, Lee, Joseph Chuen-Kwan

“…To gain insight into the real incidence of the numeric chromosomal aberrations and the cell lineage involvement of the neoplastic process in multiple myeloma…”
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Phase II study of PRO95780 plus rituximab in patients with relapsed follicular non-Hodgkin's lymphoma (NHL) by Wittebol, S., Ferrant, A., Wickham, N. W., Fehrenbacher, L., Durbin-Johnson, B., Bray, G. L.

“…Abstract only…”
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Acute monoblastic leukaemia with conjunctival tumours by Lei, K.I.K., Liew, C.T., Lam, D.S.C., Chan, A.T.C., Wickham, N.W.R.

“…We describe an unusual occurrence of bilateral conjunctival tumours in a 25-year-old woman. This was the first sign of relapse of acute monoblastic leukaemia…”
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Rapid healing of an indolent leg ulcer with topical rhGM-CSF by Hui, E P, Chan, A T, Yeo, W, Wickham, N W

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Endogenous and exogenous adenosine inhibit granulocyte aggregation without altering the associated rise in intracellular calcium concentration by Skubitz, KM, Wickham, NW, Hammerschmidt, DE

“…The effects of adenosine, adenosine deaminase (ADA), and an irreversible ADA inhibitor 2′-deoxycoformycin (DCF) on granulocyte aggregation in response to four…”
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Thrombocytopenia associated with ranitidine by Spychal, R T, Wickham, N W

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Measurement of intracellular calcium concentration in intact monolayers of human endothelial cells by Wickham, N W, Vercellotti, G M, Moldow, C F, Visser, M R, Jacob, H S

“…Intracellular calcium ([Ca++]i) plays an important role in signal transduction and cell activation. The measurement of [Ca++]i in intact monolayers of human…”
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Lupus anticoagulant induces a selective defect in thrombin-mediated endothelial prostacyclin release and platelet aggregation by Schorer, A E, Wickham, N W, Watson, K V

“…A patient with microvascular thrombosis and thrombocytopenia was found to have a high-titre lupus anticoagulant. The biological effects of the patient's lupus…”
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Severe hyponatremia due to syndrome of inappropriate secretion of antidiuretic hormone in a patient receiving interferon-alpha for chronic myeloid leukemia by Lei, K I, Wickham, N W, Johnson, P J

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Endothelial cell platelet-activating factor primes neutrophil responses: amplification of endothelial activation by neutrophil products by Vercellotti, G M, Moldow, C F, Wickham, N W, Jacob, H S

“…We have shown that platelet-activating factor (PAF) primes neutrophil (PMN) responses and enhances their ability to damage endothelial cells. Furthermore,…”
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